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January 03, 2019

Today's Rundown

Featured Story

Ex-Novartis Oncology CEO Liz Barrett joins UroGen

Ex-Novartis Oncology CEO Liz Barrett has joined UroGen Pharma. Barrett is taking over as CEO of the uro-oncology specialist at a time when it is working on a rolling NDA that could lead to its first drug approval.

Top Stories

Bristol-Myers scores first big deal of 2019 with $74B buyout of oncology bigwig Celgene

The long-predicted deal-making boom in Big Pharma started with a bang on Wednesday, as Bristol-Myers Squibb announced it will buy Celgene in a cash and stock transaction worth $74 billion. The deal values Celgene at $102.43 a share—54% higher than its closing price on Tuesday evening.

J&J takes stake in Locus’ CRISPR-based ‘Pac-Man’ antimicrobials

Just over a year after its first-round financing, CRISPR company Locus Biosciences has signed up Johnson & Johnson as its first big pharma partner and pocketed a $20 million upfront fee.

Merck bags global rights to NGM NASH drug, plans phase 2b trial

Merck has acquired the exclusive global rights to NGM Biopharmaceuticals’ treatment for NASH and Type 2 diabetes. The agreement gives Merck control of a drug designed to reduce liver fat content by selectively activating FGFR1c.

DBV CMO leaves as peanut allergy player rejigs team in wake of BLA withdrawal

Lucia Septién-Velez has stepped down as CMO of DBV Technologies. The departure of Septién-Velez is part of a wider reshuffle that gives DBV’s management a new look as it seeks to get its BLA back on track.

Tiburio launches with $31M and clinical-stage drugs for rare endocrine diseases

Drug accelerator Cydan unveiled its third orphan drug company: Tiburio Therapeutics, which starts life with $31 million in series A funding and a pair of clinical-stage compounds licensed from Ipsen.

AI player twoXAR teams up with 1ST Biotherapeutics on glioblastoma

TwoXAR has inked its third drug discovery partnership, this one with South Korea’s 1ST Biotherapeutics. Under the deal, twoXAR will identify drug candidates using its artificial intelligence platform, both partners will select promising candidates and 1ST Bio will develop them.

Otsuka taps Click Therapeutics for digital depression medicine in deal worth up to $305M

Otsuka will “commit capital to fully fund” the development of Click’s mobile application, dubbed CT-152, for major depressive disorder and to market the app worldwide.

After 4 years, it’s a no from Sanofi as it punts MyoKardia drug program deal

French Big Pharma Sanofi is walking away from a heart drug disease pact with MyoKardia ahead of data readouts coming later this year.

Resources

[Whitepaper] The 3DP Revolution: Planning Effective Brand Extension for In-Market Drugs

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[Infographic] Clinical Development Trends And The Impact On Clinical Trial Technology

New infographic shows trends in clinical development and the impact on randomization and trial supply management technology (RTSM).

[Webinar] Building the Business Case for Transformational RIM

Reduce the effort to create submissions and track registrations with a move to unified RIM. Watch the on-demand webinar.

[eBook] Digital Workflows: How to Focus Investment to Cut Costs and Drive Growth

Life sciences companies must immediately identify and realize productivity gains to drive down operational costs—or risk seeing more nimble competitors disappear into the distance. Where to begin?

[Whitepaper] Evaluating RIM Suites? Unification matters.

Learn how to spot an imposter with an integrated suite vs. one that’s unified. Read this whitepaper to learn more.

[Whitepaper] Why Life Sciences Companies Leverage Managed Regulated Infrastructures

Outer Edge Technology specializes in designing and managing regulated cloud-based infrastructures for the Life Sciences Industry – typically leveraging the AWS and Microsoft Azure platforms.

[eBook] 2018 Weekly Compendium

The Biopharma industry is moving at lightning speed and it can be a challenge to keep pace. Here at Biotech Primer we spend hours each week researching, writing, and editing original content for the Biotech Primer WEEKLY with one goal in mind: to help everyone better understand the latest science and technology driving today’s healthcare industry.

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