Featured Story | By Nick Paul Taylor Autolus Therapeutics is set to reduce its headcount by around 20% and seek a partner for one of its dual-targeted CAR-T candidates. The changes will increase Autolus’ focus on CD19 CAR-T cell therapy AUTO1 ahead of the anticipated delivery of pivotal data on the candidate next year. read more |
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 | Thank you to Catalent for sponsoring this year's JPM 2021 coverage. |
Top Stories By Nick Paul Taylor Betsy Nabel is stepping down as the president of Brigham and Women’s Hospital to enter biotech. Nabel is reportedly set to join her husband, the former chief scientific officer of Sanofi, at a stealthy new biotech startup. read more By Ben Adams Just a few weeks after being snapped up by AstraZeneca, rare disease specialist Alexion has nabbed a priority review voucher from Rhythm that can speed up the approval of one of its late-stage meds. read more By Amirah Al Idrus First Arrakis, now Ribometrix—Roche is doubling down on drugging RNA. Its Genentech unit is teaming up with Ribometrix to discover and develop small molecules for several RNA targets in a partnership worth $25 million upfront but that could exceed $1 billion in milestones down the line. read more By Amirah Al Idrus Nearly five years after founding CAR-T biotech Vor Biopharma, renowned writer and oncologist Siddhartha Mukherjee, M.D., is taking a crack at solid tumors. His new company, Myeloid Therapeutics, launches with more than $50 million to bring its myeloid cell-based treatments into the clinic. read more By Ben Adams Fierce 15 winner Dewpoint Therapeutics has added Pfizer to its growing list of pharma partners looking to tap the startup’s next-gen approach to a host of diseases. read more By Ben Adams Leaps by Bayer has led a chunky $105 million series B round for next-gen gene therapy player Senti Biosciences. read more By Conor Hale After cracking its wallet just one day earlier for a comparatively modest tuck-in deal, Hologic has opened it a little wider for a more expansive acquisition. read more By Angus Liu Scientists at the University of Washington and the U.K.’s Medical Research Council Laboratory of Molecular Biology have designed a new protein material they say could improve the efficacy of immunotherapies for a range of infectious diseases by influencing cell signaling. read more By Beth Snyder Bulik Pfizer’s got a new blue. Two new blues in fact, with the company’s rebrand and new logo design. Gone is the staid blue oval pill background, replaced by a two-tone blue double helix spiral. The new logo signals Pfizer’s “shift from commerce to science. We’ve unlocked the pill form to reveal the core of what we do,” Pfizer explains on its website. read more Resources Sponsored By: Polpharma Biologics Innovative cell lines and early process development are critical to generate a high producing cell lines alongside a USP strategy to meet high quality standards. 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Sponsored by: Catalent Pharmaceutical and biotech companies are spending years developing drugs or promising new biologics, all with the hopes of saving or enhancing patients’ lives. It’s a “race to the finish” in some cases, and the quicker a company can get its product to patients, the better. Sponsored by: Catalent In a BioPharma Dive industry survey, planning and forecasting were identified as top concerns for trial sponsors. In response to this need, the CSM team at Catalent has developed a methodology for identifying, evaluating, and proactively managing the inherent risks involved in clinical trial supply chain management. Sponsored by: Catalent Learn about a real-world example of how clinical supply management expertise was applied to overcome inventory challenges for a complex, global study. 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