Amgen powers up $1.9B deal with Generate
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Today's Rundown

Featured Story

With Alnylam in rear view, Maraganore wants to be a biotech multiplier, matchmaker and mentor

After 19 years at the helm of Alnylam, John Maraganore, Ph.D., is not wasting any time getting started on the next phase of his career.

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Top Stories

Sanofi tears up Sangamo cell therapy deal in pivot to off-the-shelf approaches

Sanofi is rethinking its approach to genomic medicines. Having worked with Sangamo Therapeutics on personalized cell therapies, Sanofi has decided to scrap the deal and shift its focus to allogeneic universal genomic medicine approaches.

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Amgen chooses Generate in $1.9B biobucks deal to churn out up to 10 multispecific drugs

Amgen wants its future drugs to be multispecific, and so the biopharmaceutical company selected Generate Biomedicines for a $1.9 billion biobucks deal to initially create five programs across several diseases.

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Novartis taps Alnylam for ambitious push to fix liver function

More than a decade after severing ties to RNAi pioneer Alnylam, Novartis has returned to the deal table for an ambitious early-stage collaboration to restore liver function in patients with end-stage disease.

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Eli Lilly taps Entos' delivery tech in $50M-plus nucleic acid pact

Eli Lilly has picked up exclusive right to Entos’ Fusogenix nucleic acid delivery technology, which it will use to research, develop and potentially sell nucleic acid-based therapeutics against targets in the central and peripheral nervous systems.

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Eikon Therapeutics snares $500M series B, pinning constellation of biotech stars to its upper ranks

Eikon Therapeutics, the drug discovery startup with a former Merck & Co. research chief at the helm, has appointed a pantheon of biotech veterans on its quest to take its live-cell imaging platform to the next level.

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Annexon shares dip 30% as patient dropouts dog midphase Huntington's trial

Annexon found out the hard way that investors do read the fine print. Despite the small biotech reporting “promising” interim results from a midphase Huntington’s disease trial, the company saw its shares plummet 30%.

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Ultragenyx granted go-ahead to up doses for Angelman antisense therapy that stalled after safety issues

Ultragenyx Pharmaceutical and partner GeneTx Biotherapeutics have been given the go-ahead to up the dose in a phase 1/2 Angelman syndrome trial of antisense treatment GTX-102 that was previously paused after some patients temporarily lost the ability to walk.

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Fierce is looking for the biggest Rising Stars in Health Tech

We’re searching for the engineers and designers who are looking to deliver on the beneficial potential of AI and new technologies in healthcare.

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Pfizer, Roche, AstraZeneca and J&J face newly revived lawsuit claiming they funded terrorism in Iraq

Pharmaceutical giants Pfizer, AstraZeneca, Roche and Johnson & Johnson will have to answer to charges that they paid bribes to win healthcare contracts in Iraq and in the process funded terrorists who killed Americans during the war. This week, a U.S. appeals court revived a lawsuit that was filed in 2017 and dismissed three years later.

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Unions go to court to get OSHA to release permanent COVID-19 protection standard

Nursing and labor unions filed a petition in a federal appeals court to force OSHA to install a permanent standard to protect front-line health workers from COVID-19.

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With sexually transmitted infections off the charts, California pushes at-home tests

California has become the first state to require health insurance plans to cover at-home tests for sexually transmitted infections such as HIV, chlamydia and syphilis.

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Resources

Research: How Buffer Prep Services Alleviate Sudden Spikes in Campaign Volume

Learn how a CDMO partnered with Thermo Fisher Scientific to manage high-volume process liquid and buffer preparation scale-up. Download the free case study from Thermo Fisher Scientific

Whitepaper: QC for ex vivo manipulated cell lines and tissues

A variety of genetic analysis methods are valuable in ensuring that ex vivo human cells to be used for cell-based therapies are correctly identified, have the correct characteristics, and are free of contaminants.

Whitepaper: Modernizing Key Clinical Trial Processes with Artificial Intelligence

This whitepaper addresses where AI can make the biggest impact in clinical trials. The stakes are too high for patients to leave decision-making to machines, but AI can lend administrative support that empowers staff and medical experts alike to carry out their jobs more effectively.

Webinar: Using Next Best to Elevate your Omnichannel Marketing Strategy

Learn how to elevate your omnichannel marketing strategy with Next Best - a combination of data and analytics, deployed to facilitate decision making.

Webinar: The Faster Path From Pre-Filled Syringe to Auto-Injector

Ypsomed and Catalent Biologics experts discuss strategies for integrated PFS manufacturing and auto-injector assembly to accelerate timelines and more in this webinar.

Whitepaper: Formulation Strategies When Transitioning From Vial to PFS

Learn how formulation development for a PFS affects manufacturing to drive the industry toward optimizing delivery of injectable products and, ultimately, improving patient care.

Whitepaper: Enhance the cost-effectiveness of your cGMP chemical supply chain

Learn how to develop a high-performing supply chain for cGMP chemicals used throughout your biologics workflow. Download the free whitepaper from Thermo Fisher Scientific

eBook: Get solutions to market faster

Read Get to Know Cloud Content Management for Life Sciences and learn how to eliminate silos across all workflows, from R&D to commercialization.

Events