Novartis gets aggressive in neuroscience BD

Today’s Big News

Jan 9, 2024

GSK, moving fast to buy Aiolos, pays $1B to challenge Amgen, AstraZeneca for asthma market


JPM24: Flagship chief says firm will have to ‘do some work’ before linking with China-based partners


JPM24, Day 2: GSK gets in on the M&A action


JPM24: Novartis 'pretty aggressive and active' in neuroscience BD, gene editing not so much, research chief says


Blueprint tears up plans, dropping 2 lung cancer programs after seeing early clinical data


CRISPR pioneer Doudna allies with Danaher for gene editing center targeting rare disease and beyond


Precision deals out CAR-T autoimmune rights to TG for $10M upfront


Athersys files for bankruptcy, sells assets to Healios in wake of stroke cell therapy’s struggles


New delivery particles for prime editors boost efficacy against retinal disease in mice

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GSK, moving fast to buy Aiolos, pays $1B to challenge Amgen, AstraZeneca for asthma market

Well, that was fast. Seventy seven days after Aiolos Bio launched publicly, GSK has disclosed a deal to buy the biotech and its phase 2 asthma treatment for $1 billion upfront and up to $400 million in regulatory milestones.
 

Top Stories

JPM24: Flagship chief says firm will have to ‘do some work’ before linking with China-based partners

Flagship CEO Noubar Afeyan says there's more work to be done before the firm starts making deals in China, two months after opening an Asia-Pacific hub in Singapore. The company launched its first U.K.-based biotech, Quotient Therapeutics, at the end of 2023.

JPM24, Day 2: GSK gets in on the M&A action, Blueprint pulls back in lung cancer

Welcome to Day 2 of the J.P. Morgan Healthcare Conference 2024 in San Francisco. Yesterday Merger Monday lived up to its name with deals for Novartis, J&J and Merck, and today, we’re also starting the day with an early deal. Check out all the updates from JPM below.

JPM24: Novartis 'pretty aggressive and active' in neuroscience BD, gene editing not so much, research chief says

Novartis’ R&D chief Fiona Marshall, Ph.D., says the company has been “pretty aggressive and active” in neuroscience-focused business development, looking for a boost to one of the company’s four key therapeutic pillars.

Blueprint tears up plans, dropping 2 lung cancer programs after seeing early clinical data

Blueprint Medicines is pulling back from one of its three areas of focus, dropping two non-small cell lung cancer (NSCLC) programs in response to early clinical data on the EGFR tyrosine kinase inhibitors.

CRISPR pioneer Doudna allies with Danaher for gene editing center targeting rare disease and beyond

The center, which will be based at the headquarters of Doudna’s own Innovative Genomics Institute (IGI), will be known as the Danaher-IGI Beacon for CRISPR Cures.

Precision deals out CAR-T autoimmune rights to TG for $10M upfront

TG Therapeutics has swooped in for rights to take Precision's off-the-shelf CAR-T to patients with autoimmune disease, paying $7.5 million upfront with another $2.5 million due in the next year.

Athersys files for bankruptcy, sells assets to Healios in wake of stroke cell therapy’s struggles

After Athersys made a last-ditch attempt in the fall to salvage the company in the wake of an unsatisfactory trial of an ischemic stroke cell therapy, the biotech has decided to sell all assets to Healios and file for bankruptcy.

New delivery particles for prime editors boost efficacy against retinal disease in mice

Prime editors delivered via a new type of virus-like particle have partially restored vision in blind mice.

JPM24, Day 1: Novartis reportedly in late talks for Cytokinetics after nabbing a Merck KGaA spinoff; J&J, Merck tie up M&A deals

The J.P. Morgan Healthcare Conference in San Francisco is back and here at Fierce Biotech, we’re going to bring you all the latest updates live from the life sciences event of the year.

JPM24: Dexcom posts billion-dollar quarter, lays out plans to sell CGMs to insulin-free users

2023 was a banner year for Dexcom. Not only did it undertake a new major product launch, but it received the largest expansion of insurance coverage in the company’s history. And it’s got the receipts to show for it.

JPM24: Nvidia expands drug discovery footprint with new Amgen, Recursion alliances

Computing behemoth Nvidia is expanding its march into drug development, announcing a new partnership with Amgen's deCode and adding Recursion to its AI-based discovery platform.
 
Fierce podcasts

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'The Top Line': The year in biotech

This week on "The Top Line," Fierce Biotech staff writer Gabrielle Masson and senior editor Annalee Armstrong look back at the year in biotech, which was defined by massive layoffs across the industry. They also discuss their favorite stories of the year, including an appearance from a popstar whose reputation precedes her.
 

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7 “Make or Break” Factors for Emerging Biopharma Companies

This e-book explores 7 factors that are critical to the success of emerging biopharma companies, whether they plan to out-license, partner, or launch & commercialize products.  It’s an essential resource for emerging companies with products in all stages of development.
 

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Digital Health Innovation: From Concept to Commercialization

The road to digital health innovation is exciting but complex and requires thoughtful navigation; this whitepaper serves as your guide through this process.
 

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