Coherus cuts TIGIT program

Today’s Big News

Jan 10, 2024

JPM24: Lilly CEO David Ricks to biotechs: 'We're open for business'


JPM 24: CRISPR Tx on active deal hunt but director cautions it's 'still early days’


JPM24, Day 3: Gene editors take the stage to talk business development, germline edits


Coherus axes TIGIT program, walking away from Junshi candidate 2 years after making $35M bet


C4 lays off 30% of staff in aftermath of BRD9 degrader discontinuation


Alcon’s dry eye ambitions take off as $770M Aerie takeover delivers phase 3 wins


Aclaris claims win for ‘soft’ JAK inhibitor but mixed data spooks investors


Fierce Biotech Layoff Tracker 2024: Affimed dissolves research and preclinical teams; 175 Exelixis employees to exit


JPM24, Day 2: GSK, Eli Lilly, Blueprint, SR One and more

The Top Line Podcast: Don’t miss out on the newest episode. Listen now.

 

Featured

JPM24: Lilly CEO David Ricks to biotechs: 'We're open for business'

Eli Lilly CEO David Ricks, speaking to the slow and steady progress that brought tirzepitide to the world, says the Indianapolis pharma is now ready to open up the chocolate factory.
 

Top Stories

JPM 24: CRISPR Tx on active deal hunt but director cautions it's 'still early days’

CRISPR Therapeutics board member Simeon George said it's "still early days" for the company's pursuit of new partners, saying more work has to be done on coming to potential deal terms.

JPM24, Day 3: Gene editors take the stage to talk business development, germline edits

We're off for another day of the J.P. Morgan Healthcare Conference 2024. The flood of licensing deals and M&A may have slowed, but there's still plenty of action to come as companies make pitches to their peers, investors and industry watchers.

Coherus axes TIGIT program, walking away from Junshi candidate 2 years after making $35M bet

Coherus BioSciences wants to get off the TIGIT rollercoaster. Less than two years after paying $35 million to exercise its option, the biotech has told Junshi Biosciences it is dropping the TIGIT asset CHS-006 from the collaboration.

C4 lays off 30% of staff in aftermath of BRD9 degrader discontinuation

A total of 45 positions will be impacted, with the changes likely to be completed by the end of the quarter.

Alcon’s dry eye ambitions take off as $770M Aerie takeover delivers phase 3 wins

Alcon’s $770 million takeover of Aerie Pharmaceuticals has delivered an early win. The lead candidate in the acquired pipeline met the primary endpoint in a pair of phase 3 dry eye trials, positioning Alcon to file for FDA approval in the middle of the year.

Aclaris claims win for ‘soft’ JAK inhibitor but mixed data spooks investors

Aclaris Therapeutics has touted the latest phase 2 results for its “soft” JAK 1/3 inhibitor as a win for the beleaguered biotech, but investors appeared to have been spooked by the wider set out mixed data.

Fierce Biotech Layoff Tracker 2024: Affimed dissolves research and preclinical teams; 175 Exelixis employees to exit

We really didn't want to have to create another Layoff Tracker this year. But here we are, launching the third annual iteration tracking biopharma layoffs. 

JPM24, Day 2: GSK, Eli Lilly, Blueprint, SR One and more

Welcome to Day 2 of the J.P. Morgan Healthcare Conference 2024 in San Francisco. Yesterday Merger Monday lived up to its name with deals for Novartis, J&J and Merck, and today, we’re also starting the day with an early deal. Check out all the updates from JPM below.

Labcorp inks collaboration with trial software firm Hawthorne Effect to speed up decentralized studies

Labcorp, which spun off its CRO arm last year, inked a collaboration deal with trial software firm Hawthorne Effect to speed up decentralized clinical trials and increase patient diversity.

JPM24: Illumina tops quarterly earnings estimates as it prepares to part with Grail

Presenting at the J.P. Morgan Healthcare Conference in San Francisco, the company reported about $1.12 billion in revenue from last year’s fourth quarter, representing a gain of 3% over the same period the year before.

JPM24, Day 3: New BioMarin CEO Hardy focused on Voxzogo; Alkermes enters new phase after busy year

On Wednesday at the the J.P. Morgan Healthcare Conference, attendees will get a chance to hear from AbbVie, Amarin and several other pharmaceutical companies.

AcelRx becomes Talphera, adopting new name to reflect pain pivot

AcelRx Pharmaceuticals wants to put a tough few years behind it. After failing to crack the pain market, the biotech has shifted its focus to a pipeline led by a blood thinner and adopted a new name, Talphera, to reflect the revised strategy.

Study: Drug interventions appear to have fewer disparities than other types of obesity care

While most behavioral and surgical treatment studies reveal disparities in weight loss and clinical outcomes, pharmacological studies reveal minimal to no evidence of disparities and favorable outcomes for minorities.
 
Fierce podcasts

Don’t miss an episode

'The Top Line': The year in biotech

This week on "The Top Line," Fierce Biotech staff writer Gabrielle Masson and senior editor Annalee Armstrong look back at the year in biotech, which was defined by massive layoffs across the industry. They also discuss their favorite stories of the year, including an appearance from a popstar whose reputation precedes her.
 

Resources

Whitepaper

Developing and Manufacturing Drugs with HPAPIs

Discover how to effectively classify highly potent APIs and the steps required to develop containment protocols and manufacturing processes that are both safe and efficient.

eBook

7 “Make or Break” Factors for Emerging Biopharma Companies

This e-book explores 7 factors that are critical to the success of emerging biopharma companies, whether they plan to out-license, partner, or launch & commercialize products.  It’s an essential resource for emerging companies with products in all stages of development.
 

Whitepaper

Digital Health Innovation: From Concept to Commercialization

The road to digital health innovation is exciting but complex and requires thoughtful navigation; this whitepaper serves as your guide through this process.
 

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