Oramed’s oral insulin fails ph. 3 diabetes test

Today's Big News

Jan 12, 2023

After rock climbing in biotech, Novartis' CMO is back to support hopeful hike to US summit


Sanofi pumps $750M into VC unit to push deeper into biotech investing


Oramed’s oral insulin flunks phase 3 diabetes test, sending stock down 70%


After hiatus, Teva looks to amp up research collaborations, CEO says


GSK grabs 150K square feet of prime Boston lab space as part of RNA, viral focus


Nektar pins comeback hopes on Lilly collab and cancer combinator following bempeg blowup


Ionis CEO admits PCSK9 ship captained by Big Pharmas may have sailed


JPM23, Day 3: Ionis CEO concedes PCSK9 ship may have sailed; Nektar forges ahead after bempeg blowup

 

Featured

After rock climbing in biotech, Novartis' CMO is back to support hopeful hike to US summit

Novartis' Chief Medical Officer Shreeram Aradhye, M.D., is back after a muscle-building stint in biotech, jumping into 2023 laser-focused on five therapeutic areas and driven by the company’s goal of becoming a top U.S. drugmaker.
 

Top Stories

Sanofi pumps $750M into VC unit to push deeper into biotech investing

Sanofi has thrown its financial weight behind its venture capital unit, making a $750 million, multi-year commitment to enable the financier to build on a year in which it backed 10 companies globally.

Oramed’s oral insulin flunks phase 3 diabetes test, sending stock down 70%

Oramed Pharmaceuticals’ dream of developing an oral insulin for type 2 diabetes looks to be over. With the candidate failing to beat placebo in a phase 3 trial, the biotech outlined plans to stop development and sent its share price tumbling in the process.

How MRD is accelerating effective use of biologic therapies

Advanced ctDNA analysis yields biomarkers of cancer dynamics essential in therapeutic monitoring & intervention. Learn how NeXT Personal® detects MRD, monitors variants, & delivers powerful insights.

After hiatus, Teva looks to amp up research collaborations, CEO says

As Teva’s new CEO Richard Francis settles into his role, he’s already sharing thoughts on strategic priorities just days into the job.

GSK grabs 150K square feet of prime Boston lab space as part of RNA, viral focus

GSK is continuing to grow its footprint in the biotech hub of Boston, adding 155,000 square feet of additional lab space to its site on Cambridge Park Drive as part of its RNA focus.

Nektar pins comeback hopes on Lilly collab and cancer combinator following bempeg blowup

Some nine months after Nektar's bempeg implosion, the company is pinning comeback hopes on two clinical-stage assets, one of which is part of a collaboration with Lilly. That asset, rezpeg, is slated for a critical phase 2 readout in lupus around mid-year.

Ionis CEO admits PCSK9 ship captained by Big Pharmas may have sailed

Ionis once had AstraZeneca involved with and spied a bright future for PCSK9 inhibitor ION449. Now, after the U.K. pharma backed out last year, CEO Brett Monia, Ph.D., thinks the drug may have missed its shot. 

What's medtech's place at the conference? CEOs from CVRx, Axogen and more weigh in

As biotech and pharma have grown in prominence at the annual J.P. Morgan Healthcare Conference, it begs the question of where medtech makers fit in at the meeting—if at all.

Pinnacle completes purchase of South Texas Research Institute with focus on NASH

Pinnacle Clinical Research, part of the LongueVue Capital portfolio, completed its acquisition of the South Texas Research Institute, which is known for its clinical research of nonalcoholic steatohepatitis.

Becerra renews COVID-19 public health emergency another 90 days, possibly for last time

HHS Secretary Xavier Becerra has extended the COVID-19 public health emergency again for another 90 days and possibly for the last time.

IMA snaps up Clinical Trials of America to extend southeast US footprint

IMA Group, parent of IMA Clinical Research, acquired Clinical Trials of America for an undisclosed sum, extending the company’s presence in the U.S. southeast.

JPM23, Day 3: Ionis CEO concedes PCSK9 ship may have sailed; Nektar forges ahead after bempeg blowup

Join us for a rolling look at the top life sciences news coming out of this year's virtual J.P. Morgan Healthcare Conference.
 
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'The Top Line': 2022's rotten tomatoes, plus this week's headlines

This week on “The Top Line,” we discuss the biotech industry’s rotten tomatoes. Plus, we cover the drug approvals of last year, a congressional report on Biogen's "inappropriate" communications with the FDA and other top headlines from this week.
 

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