Roivant’s Gline has ‘pangs of regret’ tied to Telavant sale

Editor's Note: Fierce Biotech will not publish Monday, Jan. 15 for Martin Luther King Jr. Day. We’ll be back in your inboxes Tuesday!

Today’s Big News

Jan 12, 2024

JPM24: Roche's pharma BD chief explains renewed ADC interest but is spoilt for choice


JPM24: Roivant’s Matt Gline has ‘pangs of regret’ for letting Telavant go, but he's ready to deal again


Novartis reportedly backs out of Cytokinetics deal, denting biotech’s stock


Editor’s Corner: Driverless cars and doorless planes at JPM 2024


Chutes & Ladders—Former Celgene CEO Alles takes the top job at TORL


Researchers find key to clearing precancerous cells, and with it, a potential treatment mechanism

The Top Line Podcast: Don’t miss out on the newest episode. Listen now.

 

Featured

JPM24: Roche's pharma BD chief explains renewed ADC interest but is spoilt for choice

As one of the first Big Pharmas to embrace antibody-drug conjugates, Roche plans to bet more on the popular cancer modality, Global Head of Pharma Partnering James Sabry, Ph.D., told Fierce. But biotechs looking for a Roche alliance must first meet an invisible bar.
 

Top Stories

JPM24: Roivant’s Matt Gline has ‘pangs of regret’ for letting Telavant go, but he's ready to deal again

Sometimes, you have to act while the tea is hot. For Roivant CEO Matt Gline, that meant dealing out Telavant to Roche for $7.1 billion last year, even if he wasn’t quite ready to let the vant company go.

Novartis reportedly backs out of Cytokinetics deal, denting biotech’s stock

Reuters and The Wall Street Journal have punctured investors’ hopes that Novartis will buy Cytokinetics. The Swiss drugmaker has reportedly backed away from the potential deal late in negotiations, deflating the biotech’s share price.

Editor’s Corner: Driverless cars and doorless planes at JPM24

The biotech industry has a love-hate relationship with the J.P. Morgan Healthcare Conference in San Francisco. Every year, thousands gather on the Golden Gate City and battle rain, hail, floods, what have you, just to make billion-dollar deals.

Chutes & Ladders—Former Celgene CEO Alles takes the top job at TORL

Mark Alles, who's spent the better part of the last four decades in biopharma leadership roles, has been named chairman and CEO of TORL BioTherapeutics.

Researchers find key to clearing precancerous cells, and with it, a potential treatment mechanism

Researchers have chipped away a little more at the mystery of cancer resistance, this time in the form of new findings that explain how the immune system senses DNA damage in precancerous cells. The results could offer paths not only to treatments, but even prevention.

FDA's early review finds no evidence linking Novo, Lilly weight-loss drugs to suicidal thoughts

A preliminary evaluation by the FDA found no evidence that use of popular diabetes and weight-loss drugs from Novo Nordisk and Eli Lilly can cause suicidal thoughts, the U.S. regulator said.

BioMarin’s commercial chief Jeffrey Ajer hits the exit as new CEO looks to boost launch of Voxzogo, Roctavian

Rare disease specialist BioMarin has a new CEO in Genentech’s former chief Alexander Hardy and he appears to be shaking up his commercial team as its lead Jeffrey Ajer will now leave the company by July.

ResMed’s warning on CPAP magnet interference earns FDA Class I recall tag

ResMed first warned in November that some of the masks used with its CPAP machines contain magnets that could potentially interfere with pacemakers, neurostimulators and other implanted medical devices.

CES 2024: Mark Cuban, Glen Tullman sound off on building new models of care for consumers and AI's impact

"For healthcare, the biggest issue right now is IP [intellectual property] protection and the way access to information may change going forward," entrepreneur Mark Cuban said during a CES panel.

FDA clears AI that predicts Alzheimer’s progression from an MRI scan

Described as a virtual microscope, the BrainSee program could be used before a PET scan or biopsies of cerebrospinal fluid, according to the developer Darmiyan.

Fierce Pharma Asia—Pfizer's eye for China ADC deals; Astellas' gastric cancer rejection

Pfizer mused on ADC opportunities in China, while Takeda's R&D head revealed details behind the company's competitive TYK2 deal with Nimbus at this year's J.P. Morgan Healthcare Conference. Astellas received a manufacturing-related rejection for its gastric cancer candidate. And more.
 
Fierce podcasts

Don’t miss an episode

'The Top Line': The year in biotech

This week on "The Top Line," Fierce Biotech staff writer Gabrielle Masson and senior editor Annalee Armstrong look back at the year in biotech, which was defined by massive layoffs across the industry. They also discuss their favorite stories of the year, including an appearance from a popstar whose reputation precedes her.
 

Resources

Whitepaper

Developing and Manufacturing Drugs with HPAPIs

Discover how to effectively classify highly potent APIs and the steps required to develop containment protocols and manufacturing processes that are both safe and efficient.

eBook

7 “Make or Break” Factors for Emerging Biopharma Companies

This e-book explores 7 factors that are critical to the success of emerging biopharma companies, whether they plan to out-license, partner, or launch & commercialize products.  It’s an essential resource for emerging companies with products in all stages of development.
 

Whitepaper

Digital Health Innovation: From Concept to Commercialization

The road to digital health innovation is exciting but complex and requires thoughtful navigation; this whitepaper serves as your guide through this process.
 

Industry Events

 

Upcoming Fierce Events

16-18
Jan
Virtual Event
11-12
Mar
San Francisco, CA
18-20
Mar
Savannah, GA
6-8
May
Jersey City, NJ
13-15
May
Newport Beach, CA

View all events