Featured Story | By Nick Paul Taylor Merck has stopped development of its two COVID-19 vaccine candidates after getting a look at phase 1 data. The vaccine powerhouse said neither candidate triggered immune responses comparable to those achieved by rival jabs, leading Merck to cut its losses and focus on COVID-19 therapeutics. read more |
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 | Thank you to Catalent for sponsoring this year's JPM 2021 coverage. |
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Top Stories By Nick Paul Taylor Roche’s bispecific faricimab has matched Regeneron’s Eylea in another pair of phase 3 clinical trials. The top-line results suggest the VEGFxAng2 bispecific antibody faricimab performs as well as Eylea in people with “wet” age-related macular degeneration even when it is dosed half as often. read more By Phil Taylor While big companies can shrug off a failure, the wasted investment and missed commercial opportunities can still be damaging. For smaller companies, flunking a trial can jeopardize the future of the business. read more By Amirah Al Idrus Faze Medicines has a new CEO: Philip Vickers, Ph.D., a Shire alum who most recently led cancer-focused Northern Biologics. Vickers takes over from interim CEO Cary Pfeffer six weeks after Faze emerged with $81 million to pursue medicines targeting biomolecular condensates. read more By Amirah Al Idrus Roivant CEO and founder Vivek Ramaswamy is to become the biotech builder’s executive chairman as he promotes Chief Financial Officer Matt Gline to the chief’s role. There’s less to manage these days after Roivant sold off five Vants—Myovant, Urovant, Enzyvant, Altavant and Spirovant—to Sumitomo Dainippon, which now runs them under a new company, Sumitovant. read more By Ben Adams TScan Therapeutics has raised a cool $100 million in a series C to start 2021 on the positive notes it rang throughout 2020. read more By Beth Snyder Bulik Aurinia has nabbed its first FDA approval with an OK for Lupkynis (voclosporin) to treat lupus nephritis, or kidney inflammation caused by systemic lupus erythematosus. And now it'll look to its newly bolstered commercial team to take the drug into a wide-open market. read more By Arlene Weintraub Australian researchers studied the microbiome in mouse models of asthma and were surprised to discover that the molecules L-tyrosine and p-cresol sulfate protected against lung inflammation. Now they're planning to fast-track L-tyrosine into clinical trials in asthma, and they believe it might also be effective against acute lung disease in COVID-19. read more By Conor Hale Boston Scientific has obtained approval from the FDA for the fourth generation of its Vercise Genus deep brain stimulation system, allowing conditional use while within an MRI scanner. read more |  | Experts in our field with 20+ yrs. experience in Viral Vector & Plasmid DNA (R&D, “HQ” High Quality, GMP) manufacture. Now part of the Cognate BioServices family, Your CDMO partner from concept to commercial for cell & gene therapy products. Learn more. |
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