Intranasal antibody treats stoke in rodents

This Week

Jan 25, 2023

Eyeing tissue targeting, AstraZeneca consortium gets cash for nucleic acid delivery work


Investors kibosh Midatech merger, triggering scramble for cash


Advancing node-to-brain delivery, team treats stoke in rodents using intranasal antibody


Georgia Tech spinout bags cash for nucleic acid delivery R&D

The Top Line Podcast: don’t miss out on the newest episode where we discuss ASCO data, rising health tech stars, and more. Listen now.

 

Featured

Eyeing tissue targeting, AstraZeneca consortium gets cash for nucleic acid delivery work

A consortium featuring AstraZeneca has secured funding to advance the delivery of nucleic acids, teeing the collaborators up to create new methods for getting oligonucleotide therapies to target tissues.
 

Top Stories

Investors kibosh Midatech merger, triggering scramble for cash

Midatech Pharma’s plans to pivot past its cash crunch have come unstuck. After securing financing and striking a deal to buy Bioasis Technologies, Midatech put its plans to a vote—only for investors to shoot down the proposals and leave the drug delivery specialist with weeks to find an alternative option.

Advancing node-to-brain delivery, team treats stoke in rodents using intranasal antibody

Researchers have generated more preclinical evidence that intranasal delivery can get antibodies to the brain, presenting data that suggest the administration route can achieve concentrations close to those provided by invasive intrathecal infusions.

Georgia Tech spinout bags cash for nucleic acid delivery R&D

Piezo Therapeutics has emerged as the latest startup focused on the delivery of nucleic acids, launching with $2 million in seed funding and a platform that combines electric pulses and microneedles.

Takeda pledges up to $1.13B for rights to Hutchmed's cancer drug fruquintinib outside of China

Since the start of the decade, big pharma companies from Europe and the United States have descended on China to get in on the country’s biotech boom. The latest big pharma player to get a piece of the action however is closer to home. Takeda of Japan has partnered with Hong Kong-based Hutchmed, gaining the commercial rights to colorectal cancer drug fruquintinib outside of China for $400 million up front, plus $730 million in potential milestone payments.

Call for nominations: The most influential people in biopharma in 2023

As the biopharma industry moves beyond its groundbreaking pandemic response, we're looking for leaders with ideas that'll shape the future of the industry.
 
Fierce podcasts

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'The Top Line': Highlights from Fierce's JPM Week

This week on "The Top Line," we take you inside Fierce's JPM Week event. Listen in on snippets from a lively panel discussion on how companies will navigate the drug pricing policies the Biden administration rolled out just last year. And hear from Christine Roth, head of Bayer's oncology strategic business unit, about the company's plans to become a strong competitor in cancer.

 

Resources

eBook

Orally Inhaled & Nasal Drug Delivery: A Pipeline of Opportunities

Catalent’s Carla Vozone discusses the significant trends in the Orally Inhaled & Nasal Drug Delivery (OINDP) segment including large molecules and novel indications.

Whitepaper

Catalent Pulmonary & Nasal Delivery Capabilities

Did you know Catalent has newly expanded in-house capabilities spanning clinical and commercial scale manufacturing for DPIs, unit-dose, bi-dose and preserved multi-dose nasal sprays?

 

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