GSK eyes 12 blockbuster launches to soften patent loss

Today’s Big News

Jan 31, 2024

Novartis calls time on TIM-3, axing cancer candidate after phase 3 flop 


Novo Nordisk R&D spend jumps 35% thanks to soaring sales as oral obesity plans advance


GSK tips 12 blockbuster launches to soften HIV patent loss, power sales toward $50B 


Windtree's direction shifts to full company sale amid partner hunt for cardiogenic shock program


After phase 2 fail, cell therapy biotech Atara cuts CMO and lays off 25% of staff  


Allogene parks Notch CARs, leaving one on the road  


Catamaran Bio sends out life raft in tough financing climate, ending day-to-day operations 


Avrobio's corporate tremor attracts Tectonic for reverse merger 


Biogen abandons Aduhelm efforts, focuses on Eisai-partnered Leqembi and pipeline drugs 

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Featured

Novartis calls time on TIM-3, axing cancer candidate after phase 3 flop

Novartis’ anti-TIM-3 antibody has flunked a phase 3 blood cancer trial, prompting the Swiss drugmaker to pull the drug candidate from its pipeline. The failed study was the biggest test to date of an immuno-oncology target into which a who’s who of leading drug developers have pumped money.
 

Top Stories

Novo Nordisk R&D spend jumps 35% thanks to soaring sales as oral obesity plans advance

It's early days, but Novo Nordisk’s oral, long-acting, GLP-1 and amylin weight loss drug was found to be safe and effective in a phase 1 trial, spurring plans to widen the development plan, Martin Holst Lange, EVP and head of development, told investors Wednesday. 

GSK tips 12 blockbuster launches to soften HIV patent loss, power sales toward $50B

GSK is moving to ease worries about the looming loss of exclusivity on its HIV blockbuster, setting out plans to launch at least 12 major products and deliver more than 38 billion pounds ($48 billion) in risk-adjusted sales by 2031.

Windtree's direction shifts to full company sale amid partner hunt for cardiogenic shock program

Windtree Therapeutics is doing everything possible to advance a pipeline of cardiovascular meds, but it’s still not enough. The biotech is now hunting for a buyer of the entire operation rather than just a simple licensing deal.

After phase 2 fail, cell therapy biotech Atara cuts CMO and lays off 25% of staff

After a phase 2 flop late last year, allogeneic T-cell company Atara Biotherapeutics is laying off 25% of staff and sending its chief medical officer out the door.

Allogene parks Notch CARs, leaving one on the road

Allogene Therapeutics has dropped the bulk of a cell therapy collaboration with Notch Therapeutics, leaving just one chimeric antigen receptor (CAR) target from the original deal.

Catamaran Bio sends out life raft in tough financing climate, ending day-to-day operations

Catamaran Bio’s voyage is ending early as the cell therapy biotech winds down operations and tries to find a new partner for its allogeneic solid tumor therapies.

Avrobio's corporate tremor attracts Tectonic for reverse merger

Tectonic is jumping to Wall Street through a reverse merger with Avrobio. The latter biotech waved the white flag last summer to search for buyers.

Biogen abandons Aduhelm efforts, focuses on Eisai-partnered Leqembi and pipeline drugs

Biogen is discontinuing its first Alzheimer's disease therapy, Aduhelm, after walking a rocky path. The company is taking a $60 million charge, halting sales and terminating a confirmatory trial.

Blastoff! Virtual Incision's surgical robot becomes the first sent to the International Space Station

In a giant leap for medtech-kind, a robotic surgery system is now en route to the International Space Station.
 
Fierce podcasts

Don’t miss an episode

‘The Top Line’: Closing the $1 trillion women’s health gap

While it’s a known fact that women, on average, live longer than men, a recent report unveils a nuanced reality—women also spend more of their lives grappling with poor health. This week on “The Top Line,” Ayla Ellison, editor-in-chief of Fierce Healthcare and Life Sciences, explores the root causes behind this disparity and the multifacted nature of the women’s health gap.
 

Resources

Whitepaper

Developing and Manufacturing Drugs with HPAPIs

Discover how to effectively classify highly potent APIs and the steps required to develop containment protocols and manufacturing processes that are both safe and efficient.

eBook

7 “Make or Break” Factors for Emerging Biopharma Companies

This e-book explores 7 factors that are critical to the success of emerging biopharma companies, whether they plan to out-license, partner, or launch & commercialize products.  It’s an essential resource for emerging companies with products in all stages of development.
 

 

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