Novartis axes JAK, clearing way for rival
To view this email as a web page, click here

Today's Rundown

Featured Story

Humira rings up $20.7B in 2021, but AbbVie still mum on post-biosimilar expectations

With $5.33 billion in sales in the fourth quarter, which exceeded expectations, Humira reached the elusive $20 billion mark in 2021, the company said in its quarterly sales call. As for the future of the megablockbuster, the company said it would provide 2023 guidance later this year.

read more

Top Stories

Thermo Fisher revenue climbs 22% for 2021, buoyed by product launches and the year’s biggest buyout

They say you have to spend money to make money, and that definitely proved true for Thermo Fisher Scientific in 2021.

read more

Novartis JAKs in rival to Incyte's topical eczema drug after seeing clinical data

Strike Novartis from the list of rivals to Incyte’s topical eczema drug Opzelura. After getting a look at early clinical data, Novartis has dumped its topical pan-JAK inhibitor CEE321 over an unfavorable risk-benefit profile.

read more

Unvaccinated 23 times more likely than boosted to be hospitalized during omicron wave

New Los Angeles County public health surveillance data reaffirm vaccines and boosters' protection against COVID-19, and particularly against severe illness.

read more

Gilead to fork over $1.25B, pay 3% royalty on blockbuster Biktarvy in GSK patent settlement

GlaxoSmithKline and Gilead Sciences have been duking it out in the HIV arena for years, hoping to get an edge over one another with new launches and head-to-head drug trials. Now, in a Tuesday settlement, the companies are resolving a legal dispute over lucrative patents related to GSK's HIV drug dolutegravir.

read more

Paragonix's lung transport system completes 4,700-mile, cross-country transplant

The high-stakes transplant procedure set a new record for the company’s LUNGguard system, pushing past its intended organ storage time of up to eight hours.

read more

DOJ recovers over $5B in healthcare fraud settlements, judgments in 2021

Healthcare settlements and judgements comprised the majority of the over $5.6 billion DOJ recovered in fiscal year 2021.

read more

Gilead's CD47 clinical hold expands as CEO O'Day expresses 'sense of urgency' in getting trials back on track

Gilead revealed that a partial clinical hold for its CD47 targeted cancer hopeful is larger than originally thought. Disclosed in the fine print of the pharma giant’s fourth-quarter earnings presentation Tuesday was that two more studies are subject to the hold, bringing the total number of affected trials to seven.

read more

Kindbody hits unicorn status with Vios Fertility Institute acquisition, new leadership additions

Fertility startup Kindbody hit a $1.15 billion valuation with its acquisition of Vios Fertility Institute, a deal that gives the company 13 more clinics, doubling its national footprint.

read more

How did UCB close its $1.9B deal to buy Zogenix and its key epilepsy drug? SEC filing reveals details

An SEC filing on UCB's recent acquisition of Zogenix details the negotiations it took to get the deal done and for UCB to win out over two other unnamed players.

read more

Medtronic's Hugo surgery robot used in first European procedure

Surgical teams in Europe just gained a new co-worker. A few months after earning CE mark approval, Medtronic’s robotic-assisted surgery system—dubbed Hugo—has made its European debut.

read more

Biden revives Cancer Moonshot program to seek 50% drop in cancer death rate by 2047

President Joe Biden unveiled his second attempt at a "cancer moonshot" with a renewed program focused on slashing the cancer death rate by more than 50% in the next 25 years.

read more