Trump to eliminate 'thousands' of HHS staff: reports

Today’s Big News

Feb 6, 2025

Bristol Myers Squibb, amid restructuring, unveils plan to cut another $2B in costs


Eli Lilly’s next R&D focus: Testing incretin meds in neuro, immunology fields


White House begins plan to eliminate 'thousands' of HHS employees, reports say


BD bids farewell to its diagnostic, bioscience divisions with company split


Denali eyes approval after Hunter syndrome drug clears safety measures, reduces biomarkers in open-label study


Nephrologists already aboard GLP-1 bandwagon, providing launchpad for Ozempic in CKD: Spherix

 

Featured

Bristol Myers Squibb, amid restructuring, unveils plan to cut another $2B in costs

Just nine months after announcing a massive plan to cut costs, Bristol Myers Squibb has gone one better, revealing a new goal to save even more money.
 

Top Stories

Eli Lilly’s next R&D focus: Testing incretin meds in neuro, immunology fields

Eli Lilly has invested heavily into obesity, dominating the landscape—alongside semaglutide-seller Novo Nordisk—with its blockbuster molecule tirzepatide. Now, with a pipeline chock full of numerous incretin therapies, the big pharma's new strategy will be to test some of those drugs across neurology and immunology indications.

White House begins plan to eliminate 'thousands' of HHS employees, reports say

Managers across the health agencies were tasked with categorizing their probationary workers to determine those who were not mission critical, according to two new media reports citing internal sources.

BD bids farewell to its diagnostic, bioscience divisions with company split

The “New BD,” as the company describes it, will continue on as a pure-play medtech with enterprises in medical essentials, interventional devices and connected care.

Denali eyes approval after Hunter syndrome drug clears safety measures, reduces biomarkers in open-label study

After winning a breakthrough therapy designation for its Hunter syndrome enzyme replacement therapy, Denali Therapeutics is climbing closer to its goal of accelerated approval by unveiling data showing the drug met its primary safety endpoints and reduced key biomarkers of the disease.

Nephrologists already aboard GLP-1 bandwagon, providing launchpad for Ozempic in CKD: Spherix

Nephrologists jumped on the GLP-1 bandwagon well before Novo Nordisk won FDA approval for Ozempic in chronic kidney disease, according to Spherix Global Insights.

AstraZeneca warns of potential tax fines amid China sales slowdown, illegal drug importation probe

As AstraZeneca faces an ongoing investigation into alleged illegal importation of drugs in China, the company's China business logged a sales decline in the fourth quarter of 2024.

UPDATED: Eli Lilly lops Alzheimer's and obesity assets from pipeline in Q4 update

Eli Lilly has thinned its pipeline in two critical therapeutic areas, axing clinical-phase Alzheimer’s disease and obesity candidates as part of its quarterly clear-out. Besides those cuts, the company removed eczema and heart failure prospects from its pipeline.

LinusBio to launch autism diagnostic aid that uses a single strand of hair

LinusBio aims to help physicians rule out the likelihood of autism developing in infants and toddlers under age three, and as young as one month old.

Invivyd tweaks COVID prophylactic playbook, teaming with NFL coach Harbaugh for awareness drive

Invivyd has teamed up with professional football coach Jim Harbaugh to tackle COVID-19 complacency. The biotech, which has seen sales of its COVID-19 product fall well short of expectations, is working with Harbaugh to raise awareness of how immunocompromised people can reduce the threat of the virus.

Will Gilead's twice-yearly injection dominate the HIV PrEP market? GSK doesn’t think so

The long-running HIV market rivalry between Gilead Sciences and GSK is about to turn a new page this year as Gilead looks to disrupt the pre-exposure prophylaxis field with a twice-yearly injection. But GSK, with a bimonthly option, doesn’t think its rival can hog the entire long-acting market.

Pfizer builds out oncology team with appointment of Novartis vet Jeff Legos

Pfizer is laying down new pieces for its leadership team structure, selecting Jeffrey Legos, Ph.D., to replace interim Chief Oncology Officer Roger Dansey, M.D.

Eli Lilly logs massive Q4 revenue jump—but it's not just thanks to Mounjaro and Zepbound

Thanks to impressive sales growth across multiple therapeutic areas in 2024, Eli Lilly seems to have assuaged investor concerns that its incretin drugs for diabetes and obesity were reaching a sales plateau.

AstraZeneca CEO defends 'fantastic' Alexion buyout in face of $753M hit from dropped drug

AstraZeneca has ended development of its oral factor D inhibitor vemircopan, triggering a $753 million impairment charge as the drugmaker reevaluated the worth of its Alexion acquisition. The drugmaker took another charge in relation to last year’s $2 billion push into radiopharmaceuticals.
 
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How Congress may approach healthcare reform under Trump

As the first two weeks of his second term showed, keeping up with Trump’s actions—and their ramifications—requires full-time focus. A policy expert breaks down how Congress might approach reform in 2025.
 

Resources

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The Oncology Market: 2024 Year in Review

This paper reviews key developments in the oncology market during 2024 and outlines what they mean for the future.
 

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