Pfizer steals Novartis' Legos to build oncology R&D team

Today’s Big News

Feb 6, 2025

Eli Lilly lops Alzheimer's and obesity assets from pipeline in Q4 update


AstraZeneca CEO defends 'fantastic' Alexion buyout in face of $753M hit from dropped drug


Pfizer builds out oncology team with appointment of Novartis vet Jeff Legos


Viracta Therapeutics hits end of the line, laying off all workers and winding down


X4 lays off 30% of staff, halts preclinical R&D to focus on Xolremdi rollout


Kura and Kyowa hail phase 2 win for leukemia drug soon heading to FDA, but hold back data

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Featured

Eli Lilly lops Alzheimer's and obesity assets from pipeline in Q4 update

Eli Lilly has thinned its pipeline in two critical therapeutic areas, axing clinical-phase Alzheimer’s disease and obesity candidates as part of its quarterly clear-out. Besides those cuts, the company removed eczema and heart failure prospects from its pipeline.
 

Top Stories

AstraZeneca CEO defends 'fantastic' Alexion buyout in face of $753M hit from dropped drug

AstraZeneca has ended development of its oral factor D inhibitor vemircopan, triggering a $753 million impairment charge as the drugmaker reevaluated the worth of its Alexion acquisition. The drugmaker took another charge in relation to last year’s $2 billion push into radiopharmaceuticals.

Pfizer builds out oncology team with appointment of Novartis vet Jeff Legos

Pfizer is laying down new pieces for its leadership team structure, selecting Jeffrey Legos, Ph.D., to replace interim Chief Oncology Officer Roger Dansey, M.D.

Viracta Therapeutics hits end of the line, laying off all workers and winding down

Cancer biotech Viracta Therapeutics has closed its doors, laying off all employees and winding down operations.

X4 lays off 30% of staff, halts preclinical R&D to focus on Xolremdi rollout

X4 Pharmaceuticals is laying off 30% of its staff and halting preclinical R&D as the immune system specialist channels its resources into recently approved rare disease drug mavorixafor.

Kura and Kyowa hail phase 2 win for leukemia drug soon heading to FDA, but hold back data

Kura Oncology and Kyowa Kirin claim to have scored a phase 2 win for their oral leukemia treatment while reassuring analysts about the lack of hard data to prove it.

Bristol Myers Squibb, amid restructuring, unveils plan to cut another $2B in costs

Just nine months after announcing a massive plan to cut costs, Bristol Myers Squibb has gone one better, revealing a new goal to save even more money.

Glucotrack’s 3-year diabetes sensor implant clears initial human safety trial

Glucotrack has cleared the first human clinical study of its long-term continuous glucose monitoring implant, designed to live under the skin for as long as three years.

After $2.2B Zantac settlement, GSK now faces investor lawsuit over the heartburn medication

With a $2.2 billion settlement, GSK has resolved most of its Zantac litigation. But now it faces a proposed class-action lawsuit for allegedly deceiving investors about its knowledge of a potential carcinogen in the heartburn medicine.
 
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How Congress may approach healthcare reform under Trump

As the first two weeks of his second term showed, keeping up with Trump’s actions—and their ramifications—requires full-time focus. A policy expert breaks down how Congress might approach reform in 2025.
 

Resources

Whitepaper

The Oncology Market: 2024 Year in Review

This paper reviews key developments in the oncology market during 2024 and outlines what they mean for the future.

 

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