Pharma CEOs knock PBMs at Senate hearing

Today’s Big News

Feb 9, 2024

Roche to shrink product development team, mainly impacting contractors


Moderna’s stock slumps after RSV shot efficacy wanes faster than GSK’s Arexvy


PBMs take bulk of blame as senators question BMS, J&J and Merck CEOs on high drug prices in US 


Kyverna CEO, fresh off $319M IPO, says ‘we’re in the next phase of medicine’


Zimmer Biomet to cut 3% of staff as it enters its 'growth-stage era'

 

Featured

Roche to shrink product development team, mainly impacting contractors

Roche is laying off employees within its product development team, with the total reductions slated to impact less than 6% of full-time employees in the unit. The pharma group reported 7% growth in its non-COVID business.
 

Top Stories

Moderna’s stock slumps after RSV shot efficacy wanes faster than GSK’s Arexvy

The efficacy of Moderna’s investigational RSV vaccine appears to wane faster than GSK’s approved shot Arexvy, a revelation that sent the big biotech’s stock slipping.

PBMs take bulk of blame as senators question BMS, J&J and Merck CEOs on high drug prices in US

CEOs from Bristol Myers Squibb, Johnson & Johnson and Merck faced tough questions from senators on why prices for drugs in the U.S. exceed those in other countries.

Kyverna CEO, fresh off $319M IPO, says 'we're in the next phase of medicine'

Kyverna's $319 million IPO offers more evidence that biotech's once-icy public markets are thawing. And investors are clearly clamoring for cell therapies aimed at autoimmune diseases.

Zimmer Biomet to cut 3% of staff as it enters its 'growth-stage era'

In addition to other inventory reduction initiatives, the moves are expected to cost between $125 million and $150 million through the end of 2025.

Novo Nordisk settles with 2 Florida sellers of compounded Ozempic

Novo Nordisk has reached confidential settlements with two Florida sellers of compounded versions of the mega-blockbuster semaglutide treatments Ozempic and Wegovy, the company said on Friday.

Takeda powers toward pivotal trials after phase 2b narcolepsy win but pauses multi-indication dream

Takeda’s narcolepsy work has finally yielded a phase 2b win, albeit with a blemish. After axing one asset over liver toxicity, the Japanese drugmaker’s continued faith in the mechanism has been rewarded with a primary endpoint hit—but the midphase program only supports progression in one form of the disease.

As Catalent prepares to join Novo family, CDMO's sales continue to slide

Despite some turbulence at Catalent, including an 11% sales drop for the quarter, investors still seem to be buzzed about the stock after this week’s announcement that Novo Holdings is buying out the CDMO for $16.5 billion.

Fresenius brings high-volume hemodiafiltration dialysis machine to US with FDA nod

A mounting wave of recent research argues that high-volume hemodiafiltration may significantly improve outcomes for people with kidney failure compared to standard hemodialysis treatments.

Metagenomi, Telomir head to Nasdaq this morning in double test case for preclinical IPOs

After a string of IPO success stories for clinical-stage biotechs so far this year, two companies look set to test whether they can expect the same warm reaction on the public markets this morning despite not yet having a candidate in human trials.

As cancer drug shortages persist, ASCO official urges congressional action at hearing

The oncology drug supply crisis has entered its second year, and doctors still face "impossible choices" without access to standard-of-care therapies, ASCO's chief medical officer, Dr. Julie Gralow, testified this week. At a congressional hearing, Gralow proposed recommendations that could help ease the situation.

Digital twin developer Unlearn sees double with 2nd $50M venture capital round

Echoing a previous $50 million fundraising, the new proceeds bring Unlearn’s lifetime total to more than $130 million. It will be used to build out its staff, computing power and long-term R&D projects.
 
Fierce podcasts

Don’t miss an episode

‘The Top Line’: The most anticipated drug launches of 2024

This week on “The Top Line,” we explore the most anticipated drug launches of 2024. Editor-in-Chief Ayla Ellison engages in a conversation with Fierce Pharma Marketing Senior Editor Ben Adams about the drugs likely to launch this year with the most significant sales potential by 2028.
 

Resources

Whitepaper

The Oncology Market – 2023 Year in Review

This paper offers a detailed review of key events and developments in the oncology market during 2023.  It’s a helpful “status report” that informs how the market is likely to evolve in 2024. It covers, vaccines, radiopharmaceuticals, ADCs, CAR-Ts, bi-specifics, & more.

Whitepaper

Developing and Manufacturing Drugs with HPAPIs

Discover how to effectively classify highly potent APIs and the steps required to develop containment protocols and manufacturing processes that are both safe and efficient.

 

Industry Events

 

Upcoming Fierce Events

11-12
Mar
San Francisco, CA
18-20
Mar
Savannah, GA
6-8
May
Jersey City, NJ
13-15
May
Newport Beach, CA
14-15
May
Newport Beach, CA

View all events