Lilly pads pipeline with MASH, radiopharma pacts

Today’s Big News

Feb 10, 2025

Boehringer widens fibrosis drug’s approval path after boosting lung function in 2nd phase 3 trial


NIH caps 'indirect costs' in biomedical research grants, aims to save $4B per year


Eli Lilly inks duo of deals, teaming with AdvanCell, OliX to push deeper into radiopharma, MASH


Pliant pauses phase 2 lung fibrosis trial on advice of safety committee


Kineta sells Genentech and Merck deals to investor ahead of TuHURA merger


After phase 3 miss, Relmada picks up midstage Tourette's asset from Swedish biotech


New AI-discovered protein compounds kill bacteria and fungi infecting mice: study

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Featured

Boehringer widens fibrosis drug’s approval path after boosting lung function in 2nd phase 3 trial

Boehringer Ingelheim has cemented the potential of its idiopathic pulmonary fibrosis (IPF) drug with a second phase 3 win in a related lung disease leading the drugmaker to expand the indications it will seek FDA approval for.
 

Top Stories

NIH caps 'indirect costs' in biomedical research grants, aims to save $4B per year

A new initiative rolled out under President Donald Trump’s administration is cutting billions from grants for "indirect costs" tied to biomedical research, such as facilities, equipment and administrative expenses. 

Eli Lilly inks duo of deals, teaming with AdvanCell, OliX to push deeper into radiopharma, MASH

Eli Lilly has begun the week with a bang. Early Monday morning, AdvanCell and OliX Pharmaceuticals put out news that the Big Pharma is coughing up cash to work with them on radiopharmaceuticals and metabolic-associated steatohepatitis, respectively.

Pliant pauses phase 2 lung fibrosis trial on advice of safety committee

Pliant Therapeutics has hit the breaks on a midstage trial of its lead liver disease drug on the advice of its safety committee.

Kineta sells Genentech and Merck deals to investor ahead of TuHURA merger

Kineta has found a new home for deals with Genentech and Merck & Co. Tidying up the portfolio ahead of its merger with TuHURA Biosciences, the biotech has agreed to sell the deals to an investment firm, offload a pain prospect to Pacira Pharmaceuticals and scrap its pact with GigaGen.

After phase 3 miss, Relmada picks up midstage Tourette's asset from Swedish biotech

After sharing plans to shutter last summer, Asarina Pharma has managed to sell off its Tourette syndrome candidate to Relmada Therapeutics, another struggling biotech.

New AI-discovered protein compounds kill bacteria and fungi infecting mice: study

Researchers have used artificial intelligence to identify 25 new protein compounds that can kill bacteria and fungi, including two that showed particular potency against skin and lung infections in mice.

Bristol Myers angles Breyanzi for another blood cancer as it works to close Gilead's CAR-T lead

With another trial win, Bristol Myers Squibb is touting Breyanzi as the CD19-directed CAR-T therapy with positive readouts in the most cancer types.

eGenesis announces 2nd pig kidney procedure success, as xenotransplantation field moves forward

The procedure was performed January 25 by surgeons at the Mass General Transplant Center in Boston, as part of the company’s clinical study in patients with end-stage renal disease and kidney failure. The MGH previously completed the company’s first xenotransplant surgery in March 2024.

AbbVie scores FDA nod for Pfizer-partnered antibiotic Emblaveo

Ten months after Pfizer scored approval in Europe for Emblaveo to treat complicated intra-abdominal infections, AbbVie has done the same in the U.S., winning an FDA nod for Emblaveo for the same type of Gram-negative infections.
 
Fierce podcasts

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Looking ahead at the most anticipated drug launches of 2025

This week on "The Top Line," we dig into the 10 biggest potential drug launches of 2025, predicted to rake in a combined $29 billion in annual sales by the end of the decade.
 

Resources

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The Oncology Market: 2024 Year in Review

This paper reviews key developments in the oncology market during 2024 and outlines what they mean for the future.

 

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