CSL’s biggest ph. 3 trial flops

Today’s Big News

Feb 12, 2024

Biotech bankruptcies hit 10-year peak in 2023


Gilead pays $4.3B for CymaBay, the biotech that never gave up on liver disease med


CSL's 'most ambitious' phase 3 trial ends in failure for heart attack drug


Moderna's stock slumps after RSV shot efficacy wanes faster than GSK's Arexvy 


AN2's stock craters as phase 3 lung disease trial for lead antibiotic paused over efficacy 


Medicxi merges 6 dermatology biotechs into one, adds $100M funding for launch


Kyverna CEO, fresh off $319M IPO, says 'we're in the next phase of medicine'


Athira Pharma's ALS drug boosts survival and slows motor decline in mice, as human studies planned

The Top Line Podcast: Don’t miss out on the newest episode. Listen now.

 

Featured

Biotech bankruptcies hit 10-year peak in 2023

More biotech companies filed for bankruptcy in 2023 than any year since 2010, underscoring a brutal year defined by layoffs, company closures and pipeline reprioritizations.
 

Top Stories

Gilead pays $4.3B for CymaBay, the biotech that never gave up on liver disease med

Gilead is bolstering its liver disease portfolio with the $4.3 billion acquisition of CymaBay Therapeutics, specifically for the primary biliary cholangitis med seladelpar.

CSL's 'most ambitious' phase 3 trial ends in failure for heart attack drug

CSL’s largest-ever trial has ended in failure, as the Australian pharma revealed that its cholesterol efflux enhancer was unable to reduce the risk of heart attacks.

2024 Executive Interviews at Fierce JPM Week

Fierce Life Sciences and Healthcare sit down with biotech, pharma, and healthcare executives at Fierce JPM Week.

Moderna's stock slumps after RSV shot efficacy wanes faster than GSK's Arexvy

The efficacy of Moderna’s investigational RSV vaccine appears to wane faster than GSK’s approved shot Arexvy, a revelation that sent the Big Biotech’s stock slipping.

AN2's stock craters as phase 3 lung disease trial for lead antibiotic paused over efficacy

Just five months after launching the phase 3 part of a lung disease trial for its sole clinical asset, AN2 Therapeutics is pressing pause.

Medicxi merges 6 dermatology biotechs into one, adds $100M funding for launch

What do you get when you merge six dermatology disease-focused biotechs into one? Medicxi plans to find out.

Kyverna CEO, fresh off $319M IPO, says 'we're in the next phase of medicine'

Kyverna's $319 million IPO offers more evidence that biotech's once-icy public markets are thawing. And investors are clearly clamoring for cell therapies aimed at autoimmune diseases.

Athira Pharma's ALS drug boosts survival and slows motor decline in mice, as human studies planned

Athira Pharma’s amyotrophic lateral sclerosis drug ATH-1105 appears to boost survival and reduce motor function decline in mouse models of the disease. The company intends to test ATH-1105 in humans in the first half of 2024.

Pfizer enlists Queen, Einstein and more for Super Bowl ad showing its role in the history of science

Pfizer has touched down at the Super Bowl. The Big Pharma ran its “Here’s to Science” ad at the event, framing its work to “outdo cancer” as part of a history of breakthroughs dating back to Hippocrates.

Fierce Healthcare's Fierce 15 of 2024

Meet the winners of Fierce Healthcare's Fierce 15 of 2024.
 
Fierce podcasts

Don’t miss an episode

‘The Top Line’: The most anticipated drug launches of 2024

This week on “The Top Line,” we explore the most anticipated drug launches of 2024. Editor-in-Chief Ayla Ellison engages in a conversation with Fierce Pharma Marketing Senior Editor Ben Adams about the drugs likely to launch this year with the most significant sales potential by 2028.
 

Resources

Whitepaper

The Oncology Market – 2023 Year in Review

This paper offers a detailed review of key events and developments in the oncology market during 2023.  It’s a helpful “status report” that informs how the market is likely to evolve in 2024. It covers, vaccines, radiopharmaceuticals, ADCs, CAR-Ts, bi-specifics, & more.

Whitepaper

Developing and Manufacturing Drugs with HPAPIs

Discover how to effectively classify highly potent APIs and the steps required to develop containment protocols and manufacturing processes that are both safe and efficient.

 

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