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Today's Rundown

Featured Story

Eli Lilly hands over $125M to Rigel with $835M in biobucks for RIPK1 inhibitors

Eli Lilly has penned a research and sales pact with Rigel Pharmaceuticals for its experimental med R552, a receptor-interacting serine/threonine-protein kinase 1 inhibitor.

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Top Stories

Dermavant shows deepening effects of tapinarof on psoriasis ahead of FDA filing

Dermavant Sciences has linked its plaque psoriasis prospect tapinarof to deepening improvements in outcomes over the first year of treatment. The number of responders rose in an interim analysis of a 40-week extension study, which followed successful phase 3 clinical trials that read out last year.

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Advent raises $215M to nurture another troop of biotechs

Advent Life Sciences has raised $215 million to back early-stage life science companies on both sides of the Atlantic. The fundraising positions the VC shop that founded Arrakis and KaNDy Therapeutics to place a fresh round of bets.

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Gates, Merck and Novartis-backed Adjuvant Capital raises $300M for neglected diseases

A major group of pharma and charitable groups have joined forces to raise a $300 million venture round for Adjuvant Capital as it goes after forgotten diseases across the globe.

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Evox Therapeutics reels in $95M to propel exosome-based pipeline

After a busy 2020, Evox Therapeutics is topping up its coffers to take its work to the next level. The U.K.-based biotech raised £69.2 million ($95.4 million) from the likes of OrbiMed and GV to advance a pipeline of exosome-based treatments into the clinic and further develop the technology that underpins them.

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Medtronic recalls aortic graft implant after stent fractures, patient death

Medtronic has launched a global recall of its Valiant Navion thoracic stent graft system, used to reinforce large blood vessels at risk of rupturing from an aneurysm or other injuries.

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A safer Alzheimer's drug than Biogen's aducanumab? Denali-WashU drug shows better profile in mice

In 2018, a collaboration between Washington University and Denali Therapeutics resulted in an antibody drug that showed promise as a potential Alzheimer’s therapy. Now, the team has returned with mouse data suggesting the drug might be a safer option than Biogen’s much-hyped aducanumab.

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Enrollment Showcase

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Resources

Content Hub: How to improve the virtual work you do every day

We enable virtual work — offering over-time sessions where participants are more focused, insights are more diverse and business goals are met.

eBook: Your Path to Virtualization: Eight parameters to accelerate and optimize your technology strategy

8 parameters to optimize your “Path to Virtualization” across site- and patient-centric capabilities in this Sponsor Edition eBook.

Whitepaper: Navigating the Digital Transformation Journey

Uncover the real impact of “digital transformation” with practical advice to help you plan your own transformative journey to a harmonized digital ecosystem.

Whitepaper: A Single Source of Truth: Acorn AI's Commercial Data Model

Acorn AI has developed a flexible and scalable Commercial Data Model that provides pharmaceutical companies with the data-driven insights required to respond to the industry’s ever-changing landscape. Download the whitepaper to learn how Acorn AI’s intuitive data model enables launch success and more. 

Sponsored: Lessons Learned: Best IT Practices to Secure Your Remote Workforce Now

Criminals Are Actively Exploiting The CV-19 Pandemic To Gain Entry To Enterprise Networks. Don’t Let Your Company Become A Cybercrime Statistic -- Make These Cost-Effective IT Changes Now!

Content Hub: Access resources to guide your molecule from lab to clinic

It’s an exciting time to pioneer what could be a life-changing medicine. Clear the path to the clinic with pro tips and expert insights from industry leaders.

Content Hub: Emerging Biotech Resource Center

A one-stop hub for Cytiva resources to support process development and manufacturing of your novel molecule

Executive Summary: Manufacturing Strategies to Effectively Industrialize Autologous Cell Therapies

Autologous cell therapies have seen propelled growth since 2017, with the spotlight on the first FDA approval of a chimeric antigen receptor (CAR) T cell immunotherapy, Kymriah® (tisagenlecleucel), for the treatment of relapsed/refractory B-cell acute lymphoblastic leukemia.

Research: Premier Research Resource Hub

Browse the latest learnings and insights from our clinical development professionals.

eBrief: Drug Product Process Development: Ensuring a Consistent, High-quality Biologic

Learn about drug product process development challenges and risks, the difference between innovator and biosimilar drug product process development, and more during the drug product process development phase.

Whitepaper: Achieving a Successful Drug Product Technology Transfer

Get insights on key considerations for a successful tech transfer process for manufacturing a biologic drug product, including a case study on overcoming challenges in a process transfer for a sterile diluent.

Whitepaper: The Art of Recognizing Clinical Supply Risk Factors

In a BioPharma Dive industry survey, planning and forecasting were identified as top concerns for trial sponsors. In response to this need, the CSM team at Catalent has developed a methodology for identifying, evaluating, and proactively managing the inherent risks involved in clinical trial supply chain management.

eBook: Expecting the Unexpected: Strategies for Efficient Clinical Supply Management and Forecasting

Learn how to drive excellence within the forecasting process and utilize forecasting throughout the clinical study to better plan clinical supply budgets and project timelines. Explore how to identify potential supply-related issues before they can negatively impact your study.

Events