Medtronic's spinoff plan takes U-turn

Today’s Big News

Feb 20, 2024

AbbVie CEO telegraphs retirement and prepares to pass baton to long-time deputy Robert Michael


Sanofi stumbles in HIMALAYA trial, chalking up phase 2 ALS fail in another blow to Denali alliance


Medtronic reverses patient monitoring spinoff plan, discontinues ventilator sales


AstraZeneca touts ‘overwhelming’ Tagrisso win among 3 lung cancer portfolio advancements


RAPT faces 'unfortunate and unexpected' clinical hold after liver failure in atopic dermatitis trial

 

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AbbVie CEO telegraphs retirement and prepares to pass baton to long-time deputy Robert Michael

Robert Michael, AbbVie’s current president and chief operating officer, has been tapped by the company’s board of directors to take over Richard Gonzalez’s CEO post on July 1. Gonzalez, for his part, is retiring from his role as chief executive after 11 years to become executive chairman of AbbVie’s board.
 

Top Stories

Sanofi stumbles in HIMALAYA trial, chalking up phase 2 ALS fail in another blow to Denali alliance

Sanofi’s HIMALAYA adventure has ended in failure, dealing another blow to its RIPK1 collaboration with Denali Therapeutics.

Medtronic reverses patient monitoring spinoff plan, discontinues ventilator sales

More than a year after laying out a plan to divest its patient monitoring and respiratory interventions businesses—sparking months of speculation over potential buyers—Medtronic is reworking the reorganization.

AstraZeneca touts 'overwhelming' Tagrisso win among 3 lung cancer portfolio advancements

AstraZeneca is celebrating a trio of advancements for its portfolio in non-small cell lung cancer, including an “overwhelming efficacy benefit” for Tagrisso in early-stage disease. Besides the trial result, AZ touted an FDA approval for Tagrisso's chemo combo in metastatic tumors, plus an application acceptance for a Daiichi Sankyo-partnered TROP2 antibody-drug conjugate in a patient subgroup.

RAPT faces 'unfortunate and unexpected' clinical hold after liver failure in atopic dermatitis trial

Rapt Therapeutics is reeling from an “unfortunate and unexpected” clinical hold after a patient in a phase 2 immunology trial experienced liver failure that may be related to the study drug. 

FDA approves Iovance's Amtagvi as first T-cell therapy for a solid tumor

The T-cell therapy treatment class, which has transformed the treatment of certain blood cancers, has now reached the solid tumor field thanks to an FDA approval for a first-of-its-kind immunotherapy developed by Iovance Biotherapeutics.

Elon Musk claims first Neuralink implant patient can already control a mouse with their thoughts

“Progress is good, and the patient seems to have made a full recovery, with no ill effects that we are aware of,” the Neuralink founder said Monday.

Everest to continue mRNA ascent alone after shedding Providence partnership

The collaboration between Everest Medicines and Providence Therapeutics back in 2021 marked a significant step up for the Chinese mRNA sector. Now, Everest will continue the ascent alone.

Daiichi Sankyo plots €1B expansion to beef up antibody-drug conjugate production in Germany

Aiming to beef up development and manufacturing of antibody-drug conjugates, Daiichi Sankyo is plugging roughly €1 billion ($1.08 billion) into an expansion of its production facility in Pfaffenhofen an der Ilm, Germany.
 
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'The Top Line': Gene editing's next act

This week on "The Top Line," Max Bayer from Fierce Biotech explores the future of gene editing in an interview with the CEO of Verve Therapeutics.
 

Resources

Whitepaper

The Oncology Market – 2023 Year in Review

This paper offers a detailed review of key events and developments in the oncology market during 2023.  It’s a helpful “status report” that informs how the market is likely to evolve in 2024. It covers, vaccines, radiopharmaceuticals, ADCs, CAR-Ts, bi-specifics, & more.

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Developing and Manufacturing Drugs with HPAPIs

Discover how to effectively classify highly potent APIs and the steps required to develop containment protocols and manufacturing processes that are both safe and efficient.

 

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