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March 01, 2019

Today's Rundown

Featured Story

ImmunoGen’s ADC misses endpoint in ovarian cancer phase 3

A phase 3 trial of ImmunoGen’s antibody-drug conjugate mirvetuximab soravtansine has missed its primary endpoint. The ADC failed to extend progression-free survival more than chemotherapy, driving investors to wipe 50% off its stock price.

Top Stories

Gilead’s Kite pens 10-target CAR-T tech deal with MaxCyte

Gilead’s Kite Pharma has expanded its CAR-T agreement with MaxCyte. The revised deal gives Kite the chance to apply MaxCyte’s transfection technology to up to 10 targets.

Ascletis poaches top MSD China executive as its new R&D chief

Ascletis has enticed a big pharma veteran to serve as its new head of R&D, with former MSD China global VP Zhengqing Li taking on the task.

[Sponsored] Rise in Targeted Therapies Drives Need for Flexible, Small-Volume Manufacturing

Biologics have experienced steady double-digit growth over the last 15 years and now comprise slightly more than a quarter of all New Molecular Entity (NME) FDA approvals.

Guardant’s blood test outperforms standard tissue biopsy in landmark NSCLC study

A head-to-head study pitting Guardant Health’s lung cancer blood test against standard, tissue-based testing found that the liquid biopsy was able to deliver similar results much faster and with more accuracy—which Guardant says makes the case for its blood-based genomic test to be performed first for all newly diagnosed patients.

EuroBiotech Report—Ipsen M&A, Novartis-Akcea, Anaveon, J&J-AdoRx and Immatics

In this week's EuroBiotech Report, Ipsen has struck a $1.3 billion takeover of Clementia, Novartis is licensing a cardiovascular drug and Anaveon has raised $35 million.

FiercePharmaAsia—Daiichi Sankyo shakeup; China’s first biosimilar; Sinovac ‘poison pill’ defense

Daiichi names new global R&D chief and U.S. CEO to drive collaboration between R&D and commercial; China approves the country's first biosimilar, a Rituxan copy made by a Fosun Pharma subsidiary; Sinovac uses a rare "poison pill" defense to keep rebel investors' takeover attempt at bay.

Chutes & Ladders—Doubling down on R&D, Daiichi makes changes to U.S. research unit

Daiichi Sankyo makes changes to its U.S. research unit; Immunomedics' CEO quits; and Parexel nabs another key FDA oncology staffer. Those moves plus more hirings, firings and retirings throughout the industry.

Resources

[Whitepaper] The Right Partner Can Improve Flexibility and Mitigate Risks from Forecast Inaccuracy in Biomanufacturing

The Right Partner Can Improve Flexibility and Mitigate Risks from Forecast Inaccuracy in Biomanufacturing.

[Whitepaper] How changes in drug substance processes can affect formulation

Download this whitepaper to learn more.

[Research] Maximize Pharma Marketing ROI with Digital HCP Engagement

Which HCP Touchpoints and channels are yielding the best results in today’s digital world?

[Whitepaper] Cell-Based Cancer Immunotherapies: Commercial Risk, Curative Reward

White paper outlining the key types of cell-based immunotherapies in oncology, as well as the development and commercial outlook for each.

[Whitepaper] Better Market Intelligence With Smart Search

It’s never been more challenging to stay on top of trends and innovation shaping the future of healthcare. Discover how AI can help competitive intelligence teams achieve more proactive strategies.

[Whitepaper] Clinical Validation of a Powerful Immune Assay for Patient Selection

Learn how Health Expression Models provide increased sensitivity, specificity, and accuracy for characterizing immune response in solid tumor specimens.

[Whitepaper] Host Cell Protein Analysis in Biologic Drug Development

This whitepaper reviews fundamental aspects of HCPs that pertain to biologic drug development and presents current and emerging approaches to HCP analysis.

[Whitepaper] Accelerate Time To Market Working With Industry Specialist MSP

With FDA approval imminent, start-up Life Sciences company partners with an industry focused MSP to design and manage its regulated cloud-based infrastructure to speed time to market.

[Survey] Veeva 2019 Unified Clinical Operations Survey

Share your thoughts on the life sciences industry's progress in improving study execution.

[eBook] 2018 Weekly Compendium

The Biopharma industry is moving at lightning speed and it can be a challenge to keep pace. Here at Biotech Primer we spend hours each week researching, writing, and editing original content for the Biotech Primer WEEKLY with one goal in mind: to help everyone better understand the latest science and technology driving today’s healthcare industry.

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