BMS snags new R&D complex
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Today's Rundown

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Biogen starts layoff round as the Aduhelm maker struggles with Alzheimer’s rollout

Biogen has started sending out the layoff letters to some employees in the U.S. as part of the $500 million restructuring plan unveiled in December.

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Top Stories

White House details 4-step plan to keep America open while preparing for future COVID-19 surges

The government's new National COVID-19 Preparedness Plan has four major goals: to protect against and treat COVID-19, to prepare for new variants of COVID-19, to prevent economic and educational shutdowns and to drive more vaccination outside of the U.S.

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Bristol Myers Squibb to consolidate R&D units in San Diego in new complex

Bristol Myers Squibb will soon take up residence in a new R&D campus in San Diego, California, leasing a 427,000 square foot complex in the University Town Center near La Jolla. The agreement will allow BMS to consolidate its R&D units in the area under one roof.

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Smaller smartphone accessory magnets may also pose a threat to pacemakers, defibrillators: AHA study

If these devices are carried in a chest pocket near or over the heart, they could accidentally switch off implants such as pacemakers and cardioverter defibrillators that are designed to keep a person’s pulse on track.

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AstraZeneca, Sanofi reveal mixed hand in high-stakes RSV game, with hospitalization miss tarnishing primary endpoint hit

There’s more trouble in the respiratory syncytial virus (RSV) race. Days after GlaxoSmithKline stopped its maternal vaccine studies, AstraZeneca and Sanofi have revealed their antibody prospect failed to reduce infant hospitalization in a phase 3 clinical trial. 

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Civica Rx to make, distribute low-cost insulin

Civica plans to make three generic insulins, the price of which will be based on the cost of development, production and distribution.

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Billionaire Sackler family enters $6B opioid deal with support from holdout states

When OxyContin maker Purdue Pharma and its founding family inked a $4.5 billion opioid settlement back in September, the judge overseeing the case called it a "bitter result." Now, thanks to an appeal and extended talks, the settlement just got a lot bigger.

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Roche, Sanofi, Novo Nordisk and more pledge support to Ukraine as industry condemns Russian invasion

The contingent of pharma companies condemning Russia’s invasion of Ukraine—and pledging to help keep the beleaguered nation’s healthcare system afloat—is growing.

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As Russia stacked troops on Ukraine's border, Karuna's trial partners got ready

When Russia began to stack troops along Ukraine's border—up to 190,000 of them—Karuna Therapeutics' partners began to prepare clinical trial participants for the company's schizophrenia treatment in psychiatric hospitals across the country.

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DarioHealth lands $30M deal with Sanofi to expand commercial reach of its digital therapeutics

Chronic care management company DarioHealth signed a $30 million multi-year contract with Sanofi to extend the commercial reach of its digital therapeutics to the pharma giant's health plan clients.

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Regeneron loses bid to scrap infringement lawsuit linked to COVID antibody cocktail

Pfizer and BioNTech recently emerged from a lawsuit unscathed after Allele Biotechnology and Pharmaceuticals cried patent infringement against a trio of pandemic juggernauts. For Regeneron, however, the legal battle is set to roll on.

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UT Austin scientists design safer Cas9 with improved CRISPR gene editing accuracy

Scientists at the University of Texas at Austin have refined the Cas9 protein used in the CRISPR gene-editing tool. The new version, dubbed “SuperFi-Cas9,” was thousands of times less likely to perform off-target editing while maintaining the efficiency of on-target editing as the original version.

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FDA clears Gleamer’s X-ray AI for spotting broken bones

The Paris-based company's computer-assisted diagnostic system aims to help ER physicians as well as orthopedic surgeons and family doctors.

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Biogen's Aduhelm still has blockbuster potential if everything breaks right: analyst

A recent doctors' survey, conducted by RBC Capital Markets, shows a strong market exists for Aduhelm or similar beta-amyloid antibodies. If restrictions are loosened or if Biogen gets a positive readout in a phase 3 trial, the analysts see the potential for $8 billion in peak sales from the company's Alzheimer's franchise. The report comes amid another appeal from Congress to reconsider limiting use of the drug to clinical trials.

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