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March 05, 2018

Today's Rundown

Featured Story

Celgene pays $101M to work with Vividion on hard-to-drug proteins

Celgene has paid $101 million to collaborate with Vividion on the discovery of small molecules that hit hard-to-drug proteins. The four-year alliance tasks Vividion with discovering drugs that interact with the ubiquitin proteasome system cells used to break proteins apart.

Top Stories

Dermira dumps acne drug after phase 3 flubs

After pulling the plug on its acne drug, olumacostat glasaretil, Dermira will refocus on its pipeline programs for atopic dermatitis and excessive sweating.

Prime Minister Theresa May calls for U.K. to stay in EMA after Brexit

Britain's prime minister has called for the U.K. to remain part of the European Medicines Agency (EMA) after Brexit. The proposal jibes with the wishes of the biopharma industry, but it remains to be seen whether the European Union is receptive to the idea.

Homology seeks $100M from IPO, reveals Novartis deal numbers

Just a few weeks after signing a big deal with Novartis—now confirmed to have included $35 million upfront and almost $1 billion in milestones—Homology Medicines has pushed ahead with plans for a $100 million IPO.

Patient deaths, FDA hold cloud Unum’s $86M IPO bid

Unum revealed more than its IPO goals in an SEC filing Friday: a clinical hold on, and two patient deaths in, a phase 1 trial in non-Hodgkin's lymphoma.

Resources

[Whitepaper] Medical Device Innovation: Are You Outrunning The Competition?

The competitive landscape in medical device R&D is tough. And simply investing in R&D is no guarantee for profitability. So how do you accelerate time-to-market?

[Webinar] Driving Market Access through Patient Advocacy: Trends & Opportunities

There’s no magic bullet to successful access but insights from patient advocates and industry experts can help shape future strategies. Learn how in this webinar. Sign up now!

[Whitepaper] How Life Sciences Companies Use Box for Regulated Content in the Cloud

Learn how biopharma and medical device companies can now collaborate on, manage and distribute regulated clinical, lab and manufacturing content in Box. That means all of your content is standardized on a single content repository that meets regulatory and compliance standards, so you can eliminate inefficient silos, enable seamless collaboration and accelerate the validation process.

[Whitepaper] CFO's, Is This Part Of Your Corporate TO DO List?

Employee stock option trading & administration, Restricted stock transactions (Rule 144), Affiliated trading plans (10b5-1), Directed share plans, Equity comp plan administration — private to public

[Whitepaper] Choosing the Right Solution: Improving the Site Feasibility Process

Selecting the right sites to conduct your clinical trials will determine the success or failure of meeting your enrollment goals.

[Whitepaper] How Do Sponsors Ensure Quality in Global Clinical Trials?

Global clinical trials are the trend and gaining in popularity, but running a global trial is not a straightforward process. This white paper explores some of the challenges associated with global clinical trials and considerations for ensuring that the collected data comply with the trial's overall objectives.

[Webinar] Validating a 7 Day Membrane Filtration Sterility Test using Celsis®

Join us as we discuss how Charles River Celsis® helped Labor L+S AG validate a 7-day membrane filtration sterility test using existing protocols.

[Infographic] Evolution of Flexible Commercial Biologics Manufacturing

Learn how Catalent Biologics is paving the way for flexible biologics development and manufacturing through advanced technologies and fully integrated multi-product facility.

[eBook] Developing Site-specifically Modified ADCs: Using a Chemoenzymatic Approach

Download the eBook to get articles from various Elsevier journals highlighting developments in ADC technology.

[Article] Optimizing titer and use of a specific enzyme for generating a fully processed antibody

Learn how cell development and process scale-up can be optimized for antibodies requiring additional processing.

[Webinar] Within-Subject Clinical Trials: Intro to New Methods & Stat. Models

In this webinar, we will introduce the rapidly-evolving within-subject clinical trial (WSCT) methods for early phase evidence generation that require fewer people, less time, and usually less funding than traditional early phase methods.

Events

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