Today's Rundown Servier bags expanded rights to Cellectis' CD19 CAR-Ts Makena mess, CEO exit; now, AMAG loses CMO as pipeline comes into sharper focus PsiOxus lures Lillie from Merck to fill CMO position Novartis taps Orionis to pursue 'historically elusive targets' MacroGenics chief medical officer hits the exit Can CAR-T cells built with scorpion venom kill glioblastoma tumors? FDA bans electric shock devices for conditioning against aggressive behaviors UPDATED Coronavirus tracker: Moderna vaccine trial starts enrolling; California in state of emergency Featured Story | | | Thursday, March 5, 2020 Cellectis has revised its deal with Servier, granting its partner worldwide rights to all its CD19 CAR-T therapies in return for €25 million ($27.6 million) and the control of candidates against five additional targets. |
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Top Stories Thursday, March 5, 2020 AMAG Pharmaceuticals is losing its CEO, likely having a drug pulled off the market by the FDA and has cut more than 100 staffers; as it turns more deeply to its pipeline, the person in charge of that is now leaving. Thursday, March 5, 2020 PsiOxus Therapeutics has hired Tom Lillie away from Merck to work as its chief medical officer. Lillie’s arrival coincides with the initiation of a phase 1 trial of PsiOxus’ quadrivalent viral gene therapy vector. Thursday, March 5, 2020 Novartis has entered into a four-year research collaboration with Orionis Biosciences. The agreement tasks Orionis with applying its technologies to “historically elusive targets” in multiple therapeutic areas. Thursday, March 5, 2020 Just a month after getting its BLA accepted by the FDA for its next-gen breast cancer hopeful, MacroGenics’ SVP of clinical development and CMO Jon Wigginton, M.D., is set to leave the company later this month. Wednesday, March 4, 2020 Scientists at City of Hope have designed a novel chimeric antigen receptor (CAR) based on chlorotoxin (CLTX), a toxin found in scorpion venom. The novel CAR-T cell therapy successfully killed glioblastoma tumors with minimal off-target events and will now be ushered into clinical testing. Wednesday, March 4, 2020 The FDA has exercised a rarely used authority to completely ban a product from the market: the use of electric shock devices for conditioning a person against self-harm or aggressive behaviors. Thursday, March 5, 2020 Moderna's vaccine is nearly set for testing as investigators recruit trial participants in the Seattle area. The biotech's CEO, Stephane Bancel, has pledged to be "thoughtful" about the price. Meanwhile, the U.S. House of Representatives passed a major spending bill that includes billions for R&D and $300 million to purchase potential vaccines and therapeutics for the public. Enrollment Showcase | | | Presented by: Global EMBA for Healthcare & the Life Sciences, University of Toronto Prepare to step up in your career, build the expertise you need to reshape your organization, and explore opportunities worldwide. |
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