Vir, GSK COVID-19 antibody slashes hospitalizations and deaths in phase 3, spurring FDA filing plans Aelix posts HIV vaccine data ahead of Gilead combo readout Lilly rejoins KRAS race with swipe at Amgen and Mirati, plans 2021 clinical trial Slaoui’s Centessa adds ex-FDA commish Califf, biotech bigwigs to its board PhaseBio taps a manufacturing partner as it eyes 2022 filing for Brilinta-reversing drug Roche's Actemra adds another failure to spotty COVID-19 results—this time with Gilead's remdesivir Northwestern U's novel gene-silencing RNA drug shows promise in glioblastoma Featured Story | By Nick Paul Taylor Vir Biotechnology and GlaxoSmithKline are stopping a phase 3 clinical trial of their COVID-19 antibody early for efficacy after seeing an 85% reduction in hospitalization or death at an interim review. The trial provided further evidence of the efficacy of anti-SARS-CoV-2 antibodies in ambulatory patients. read more |
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Top Stories By Nick Paul Taylor Aelix Therapeutics has presented phase 1/2a data on its therapeutic HIV vaccine candidate. Buoyed by the results, Gilead-partnered Aelix is preparing to raise cash and push into larger trials in pursuit of a functional cure for the disease. read more By Nick Paul Taylor Eli Lilly has rejoined the KRAS race months after toxicity forced it to dump its first candidate. The Big Pharma is set to enter phase 1 later this year with a new drug it compared favorably to rival assets developed by Amgen and Mirati Therapeutics. read more By Amirah Al Idrus Centessa Pharmaceuticals is adding a trio of new board members and a new chief financial officer to its roster. Gregory Weinhoff, arrives from Arvelle Therapeutics where he served as chief financial and chief business officer. Joining the board are former FDA commissioner, Robert Califf, former Tesaro chief operating officer, Mary Lynne Hedley, and CRISPR Therapeutics CEO Samarth Kulkarni. read more By Amirah Al Idrus PhaseBio is signing a manufacturing partner for its Brilinta reversal agent as it ushers the drug through phase 3 and, it hopes, an FDA submission and approval. The company is teaming up with CDMO BioVectra to produce the treatment, bentracimab, at commercial scale. read more By Angus Liu Roche’s arthritis therapy Actemra posted another COVID-19 failure, further muddying a pool of data that has yet to offer a conclusive answer to the anti-inflammatory drug’s pandemic role. But this flop—in a combo test with Gilead's standard-of-care remdesivir—may bear more weight. read more By Angus Liu Scientists at Northwestern University have developed a novel RNA interference drug that targets the cancer-promoting Bcl2L12 gene in glioblastoma tumors. A new study in a small number of patients showed that it can penetrate the blood-brain barrier. read more Enrollment Showcase | Sponsored by: University of Florida College of Pharmacy Learn about the Top 5-Ranked UF College of Pharmacy’s online graduate programs in pharmaceutical outcomes & policy. Select from five specializations, including the new pharmaceutical value assessment & communication option. Over half of graduates progress to a new role within one year. Register now. |
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