Flagship unveils new AI biotech with $200M seed round

Today’s Big News

Mar 11, 2025

Pfizer, Arvinas post mixed breast cancer survival results in first phase 3 test for a PROTAC degrader


In buying cell therapy partner 2seventy bio for $286M, BMS takes full control of Abecma


With $200M in seed funding, Flagship-backed Lila Sciences touts ambitious AI vision


J&J opts out of licensing Genmab's Darzalex challenger after look at phase 1/2 data


Coherus to lose 30% of staff as part of Udenyca sale to Accord


Beam gene therapy for protein deficiency passes early safety test, sets efficacy bar in space: analyst


Daiichi taps Nosis to deliver RNA therapies beyond the liver


Immunocore T-cell engager clears safety hurdle, reduces HIV reservoir in some patients

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Featured

Pfizer, Arvinas post mixed breast cancer survival results in first phase 3 test for a PROTAC degrader

Pfizer and Arvinas’ estrogen receptor degrader has failed a key part of its first phase 3 test, although the companies have pointed to success in a subpopulation to suggest the therapy still has a path to regulators.
 

Top Stories

In buying cell therapy partner 2seventy bio for $286M, BMS takes full control of Abecma

More than a year into a strategic pivot to zero in on the multiple myeloma cell therapy Abecma, 2seventy bio is selling itself to partner Bristol Myers Squibb.

With $200M in seed funding, Flagship-backed Lila Sciences touts ambitious AI vision

Biotech incubator Flagship Pioneering has uncorked its latest company. Lila Sciences is looking to use $200 million in seed funding to develop advanced artificial intelligence that can power fully autonomous research labs.

J&J opts out of licensing Genmab's Darzalex challenger after look at phase 1/2 data

Johnson & Johnson is dropping a partnership with Genmab centered around a CD38 monoclonal antibody, prompting the latter company to discontinue development of the program.

Coherus to lose 30% of staff as part of Udenyca sale to Accord

Coherus BioSciences will see its workforce shrink once again as a result of the recent sale of its Neulasta biosimilar to Accord BioPharma.

Beam gene therapy for protein deficiency passes early safety test, sets efficacy bar in space: analyst

Boston biotech Beam Therapeutics has announced initial data from a phase 1/2 trial of its gene therapy for a genetic lung and liver disease, with no serious adverse events reported among the nine patients dosed so far.

Daiichi taps Nosis to deliver RNA therapies beyond the liver

Daiichi Sankyo is stepping up its interest in RNA therapies, teaming with Nosis Biosciences to design drug candidates capable of reaching targets beyond the liver.

Immunocore T-cell engager clears safety hurdle, reduces HIV reservoir in some patients

Immunocore’s big swing for a functional HIV cure has cleared its first hurdle. No serious adverse events were tied to the British biotech’s bispecific T-cell engager in a phase 1/2 trial, and the investigational treatment also reduced virus levels in the blood of three patients living with HIV.

Roche overhauls Spark gene therapy unit, recording $2.4B in full impairment

Roche has recently launched a “fundamental reorganization” of Spark Therapeutics, the gene therapy unit that the Swiss pharma bought for $4.3 billion in 2019.

Canadian CRO Innovaderm rebrands to Indero to reflect expanded rheumatology focus

Montreal-based CRO Innovaderm Research has rebranded with immediate effect to Indero, the latest change in an effort to become dually focused on both rheumatology and dermatology.

'Medical gaslighting' tops patient safety concerns for 2025, ECRI warns

An annual list of the 10 biggest threats to patient safety highlights the risk of doctors ignoring or dismissing patient concerns, either due to clinicians' unrecognized bias or time constraints. Other top concerns cited by the healthcare safety group included insufficient AI governance and medical misinformation.
 
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A look at biotech's biggest money raisers of 2024

This week on "The Top Line," we dig into several of the biggest private funding rounds in biotech last year and discuss the shifting VC landscape.
 

Resources

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The Oncology Market: 2025 Outlook

Read about four trends that will shape the innovations, therapies, & market landscape in oncology during 2025 & beyond.
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Discover how to revolutionize your vaccine trials with Avacare's latest white paper. Gain exclusive access to innovative, data-driven recruitment strategies that ensure diverse, efficient, and high-quality vaccine trials.
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Develop your CAR molecule faster
 

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