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March 14, 2018

Today's Rundown

Featured Story

House votes down right-to-try bill

The House of Representatives has rejected a bill that would have cut the FDA out of the process for clearing terminally ill patients to access experimental medicine. House Democrats voted overwhelmingly against the law, resulting in it falling just short of the required two-thirds majority.

Top Stories

Auris’ tinnitus drug fails in phase 3 again 

Auris Medical’s tinnitus candidate Keyzilen has missed the primary endpoint in a phase 3 trial for the second time. The result wiped 37% off Auris’ already-depressed stock as its slim chance of salvaging the program faded.

Crinetics raises $63.5M for oral acromegaly therapy

Perceptive leads a Series B round that will fund Crinetics' CRN00808 candidate through proof-of-concept studies as an alternative to injectable therapy for the disease.

Flagship launches Foghorn Therapeutics with $50M investment

Foghorn Therapeutics seeks to unravel how chromatin regulation malfunctions and develop drugs to correct these problems and treat cancer.

FierceBiotech Radio: #FierceMadness and a peek into the drug-naming process

Fierce editors discuss this year's #FierceMadness drug-name tournament, while Brand Institute's Scott Piergrossi explains how drugs get their names.

Quest to shutter Michigan lab, let go of 57 workers in coming months

Quest Diagnostics, the New Jersey-based diagnostics maker, will close its Troy, Michigan, laboratory by early May, laying off 57 workers at the facility.

#FierceMadness gets serious with 64 drug names, including play-in victors Taltz, Nerlynx

After a bruising two-day play-in, we have our first round of winners in this year’s drug name tournament challenge. Symproic, Nerlynx, Taltz and Giapreza move into the round of 64 after defeating their opponents handily. Now it’s time to roll up your sleeves and vote your 32 picks.

Resources

[Whitepaper] Medical Device Innovation: Are You Outrunning The Competition?

The competitive landscape in medical device R&D is tough. And simply investing in R&D is no guarantee for profitability. So how do you accelerate time-to-market?

[Webinar] Driving Market Access through Patient Advocacy: Trends & Opportunities

There’s no magic bullet to successful access but insights from patient advocates and industry experts can help shape future strategies. Learn how in this webinar. Sign up now!

[Whitepaper] CFO's, Is This Part Of Your Corporate TO DO List?

Employee stock option trading & administration, Restricted stock transactions (Rule 144), Affiliated trading plans (10b5-1), Directed share plans, Equity comp plan administration — private to public

[Whitepaper] Choosing the Right Solution: Improving the Site Feasibility Process

Selecting the right sites to conduct your clinical trials will determine the success or failure of meeting your enrollment goals.

[Whitepaper] How Do Sponsors Ensure Quality in Global Clinical Trials?

Global clinical trials are the trend and gaining in popularity, but running a global trial is not a straightforward process. This white paper explores some of the challenges associated with global clinical trials and considerations for ensuring that the collected data comply with the trial's overall objectives.

[Webinar] Validating a 7 Day Membrane Filtration Sterility Test using Celsis®

Join us as we discuss how Charles River Celsis® helped Labor L+S AG validate a 7-day membrane filtration sterility test using existing protocols.

[Infographic] Evolution of Flexible Commercial Biologics Manufacturing

Learn how Catalent Biologics is paving the way for flexible biologics development and manufacturing through advanced technologies and fully integrated multi-product facility.

[eBook] Developing Site-specifically Modified ADCs: Using a Chemoenzymatic Approach

Download the eBook to get articles from various Elsevier journals highlighting developments in ADC technology.

[Article] Optimizing titer and use of a specific enzyme for generating a fully processed antibody

Learn how cell development and process scale-up can be optimized for antibodies requiring additional processing.

[Webinar] Within-Subject Clinical Trials: Intro to New Methods & Stat. Models

In this webinar, we will introduce the rapidly-evolving within-subject clinical trial (WSCT) methods for early phase evidence generation that require fewer people, less time, and usually less funding than traditional early phase methods.

Events

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