To view this email as a web page, click here

   Home

Subscribe

Advertise

 

 

 

 

March 19, 2019

Today's Rundown

Featured Story

Urovant slips as generic holds its own against overactive bladder drug in phase 3

Urovant Sciences’ vibegron has hit the co-primary endpoints in a phase 3 overactive bladder trial. But with the drug failing to clearly outperform a generic used as an active control, the results leave room to doubt whether vibegron poses a big threat to Astellas’ Myrbetriq.

Top Stories

Biogen-Nightstar deal sheds light on gene therapy feeding frenzy

The level of interest in gene therapies has been laid bare by a report on Biogen’s pursuit of Nightstar Therapeutics. Biogen ultimately landed its target with an $877 million (€772 million) all-cash offer, but only after seeing off interest from three other companies.

ACC: After acing early trial, PhaseBio pushes forward with Brilinta-reversing drug

PhaseBio reported phase 1 data for its Brilinta (ticagrelor) reversal agent on Sunday that showed the drug quickly reversed the antiplatelet effects of Brilinta without causing serious side effects. The company plans to kick off a phase 2a study in the first half of this year.

Unlocking a secret of the anti-cancer gene p53

The gene p53 has long been a target of intense research in the oncology community because, in its unaltered form, it suppresses cancer. Now a team at the University of Wisconsin-Madison has discovered an enzyme that acts as a key regulator of the p53 protein, a finding they believe could inspire new ideas for targeting p53 with drugs.

Venclexta trial deaths force AbbVie, Roche to stop recruiting myeloma patients

AbbVie and Roche are looking to move key oncology drug Venclexta deeper into the blood cancer arena, but their ambitions just took a hit. After flagging deaths in a phase 3 multiple myeloma trial, the FDA put all of Venclexta's studies in that disease on partial hold.

Resources

[Case Study] TriCore Reference Laboratories Transforms to Clinical Lab 2.0 Model

Analytics using patients’ real-time longitudinal laboratory results, and claims data, yielded higher value information and new revenue streams for TriCore reference laboratories.

[Whitepaper] Accelerating Clinical Trials through Access to Real-World Patient Data

Whitepaper on leveraging normalized real-world patient data to streamline clinical trials, reduce delays and lower costs.

[Article] Are you ready for 2008 Microsoft SQL and Windows Servers end of life?

Software end of life puts you at risk for data breaches, business disruption and liability.

[Whitepaper] The Right Partner Can Improve Flexibility and Mitigate Risks from Forecast Inaccuracy in Biomanufacturing

The Right Partner Can Improve Flexibility and Mitigate Risks from Forecast Inaccuracy in Biomanufacturing.

[Whitepaper] How changes in drug substance processes can affect formulation

Download this whitepaper to learn more.

[Research] Maximize Pharma Marketing ROI with Digital HCP Engagement

Which HCP Touchpoints and channels are yielding the best results in today’s digital world?

[Whitepaper] Cell-Based Cancer Immunotherapies: Commercial Risk, Curative Reward

White paper outlining the key types of cell-based immunotherapies in oncology, as well as the development and commercial outlook for each.

[Whitepaper] Better Market Intelligence With Smart Search

It’s never been more challenging to stay on top of trends and innovation shaping the future of healthcare. Discover how AI can help competitive intelligence teams achieve more proactive strategies.

[eBook] 2018 Weekly Compendium

The Biopharma industry is moving at lightning speed and it can be a challenge to keep pace. Here at Biotech Primer we spend hours each week researching, writing, and editing original content for the Biotech Primer WEEKLY with one goal in mind: to help everyone better understand the latest science and technology driving today’s healthcare industry.

Events