Abbott’s rapid TBI blood test nabs new FDA clearance

Today’s Big News

Apr 1, 2024

AstraZeneca CEO's 2024 pay proposal under fire from influential proxy advisers 


No reprieve for biopharma layoffs in Q1: Fierce Biotech analysis


Abbott advances its hand-held, rapid blood test for TBI, concussions with new FDA clearance


European prosecutors take over investigation into deal for Pfizer COVID vaccines: Politico


Carisma lets go of 37% of staff, CAR-M candidate to stretch cash runway 


#FierceMadness: Mounjaro, Daybue sneak into round 4 as Beyfortus dominates; now vote in the Elite 8 round 


ZimVie begets Highridge Medical with completed spine business spinout 

 

Featured

AstraZeneca CEO's 2024 pay proposal under fire from influential proxy advisers

Like clockwork, AstraZeneca CEO Pascal Soriot’s pay is under fire again. The two most influential proxy advisory firms are rallying investors to vote against the 2024 pay proposal for Soriot at the company’s annual general meeting this month.
 

Top Stories

No reprieve for biopharma layoffs in Q1: Fierce Biotech analysis

The biotech industry has been holding its breath, hoping that 2024 would bring some reprieve from 2023’s brutal bear market. But market recovery is a slow process, and the number of layoffs reported this quarter reflect that sentiment, with 57 layoff rounds reported for the first three months—the exact number reported during the same period last year.   

Abbott advances its hand-held, rapid blood test for TBI, concussions with new FDA clearance

You won’t see Abbott’s i-STAT Alinity test on the sidelines of sporting events just yet—but the FDA’s green light is a step in that direction, allowing the use of whole blood samples.

European prosecutors take over investigation into deal for Pfizer COVID vaccines: Politico

The European Public Prosecutor’s Office (EPPO) took over the investigation into COVID vaccine negotiations between the European Commission's president and Pfizer's CEO Albert Bourla, Politico reports.

Carisma lets go of 37% of staff, CAR-M candidate to stretch cash runway

Carisma Therapeutics plans to let go of 37% of staffers and drop one of two clinical assets in an effort to fuel the immunotherapy-focused biotech into the third quarter of 2025.

#FierceMadness: Mounjaro, Daybue sneak into round 4 as Beyfortus dominates; now vote in the Elite 8 round

It’s March, so it’s time for some #FierceMadness. Last year, we channeled the NCAA tournament for the best pharma ad campaigns, but this year we’re looking for the best of the best in drug names.

ZimVie begets Highridge Medical with completed spine business spinout

First announced last December, the $375 million deal will see the launch of an independent, Colorado-based maker of screw and plate implants, fixation systems and bone healing technologies, among other spine products, under the new banner Highridge Medical.

Eisai, Biogen's injectable Leqembi delayed as FDA asks for more data

What analysts viewed as a potential “inflection point” for Eisai and Biogen’s slow-footed Leqembi is facing a delay with the FDA.

Equillium’s lupus drug improves kidney biomarker, teeing up opt-in decision from Ono

Equillium’s add-on lupus treatment improved a biomarker of kidney function in an unblinded phase 1 study, setting the ball rolling toward Ono Pharmaceuticals’ court for future development work. 

AstraZeneca's rare disease add-on therapy Voydeya scores FDA nod

With AstraZeneca’s dominance in the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) threatened by the recent approval of the first pill on the market for the condition, Novartis’ Fabhalta, AstraZeneca has answered in the United States for its add-on oral treatment in the indication.

Could immunotherapy prevent breast cancer before it starts?

Researchers for the first time have identified dysfunctional immune cells in the healthy breast tissue of women with mutations in the genes BRCA1 and BRCA2, a finding that opens up the possibility of using existing immunotherapy drugs to prevent cancer before it forms.

‘Saturday Night Live’ sends up Ozempic craze in Ramadan-themed parody ad

The fake product's packaging describes it as a pork-free semaglutide injection and “100% halal food”—complete with real Ozempic maker Novo Nordisk’s branding.
 
Fierce podcasts

Don’t miss an episode

'The Top Line': The top money raisers in biotech

This week on "The Top Line," we explore our annual special report on the top money raisers in the biotech industry. Which company raised the most funding in 2023? What does the biotech financing landscape look like for this year? Fierce Biotech's Annalee Armstrong and Max Bayer answer those questions and many more in today's episode.
 

Resources

Whitepaper

Oncology Market Outlook 2024

This paper assesses the current state of the oncology market, reviewing key expectations for 2024. It addresses CAR-T therapies, KRAS, radiopharmaceuticals, & targeted protein degradation.
Whitepaper

Guidance for Biotechs Choosing Next-Gen Contract GMP/CMC Labs

Choosing the right contract lab can help drug developers accelerate their timelines and generate cost-efficiencies. For insights into what to look for when selecting a GMP/CMC lab partner read this white paper which delves into a range of factors that can support your needs in both the short-term and in planning for the future.
 

Industry Events

Drug Development Boot Camp® VIRTUAL | Spring 2024

April ‌10-11, ‌2024

On Helix

Date: ‌4 ‌July ‌2024 ‌- ‌Location: ‌Babraham ‌Research ‌Campus, ‌Cambridge ‌UK

 

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