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April 08, 2019

Today's Rundown

Featured Story

Sanofi, Alnylam officially end their RNA pact as Regeneron jumps in

Over the past year, Sanofi and Alnylam have been retooling their 2014 R&D pact around Alnylam's RNA tech; today, the pair signaled its end, and former Sanofi partner Regeneron has stepped in.

Top Stories

United Therapeutics tosses out esuberaprost after trial flop

United Therapeutics is throwing its pulmonary arterial hypertension drug esuberaprost on the scrap heap after failing in a phase 3 test.

Trevi Therapeutics jumps on the biotech IPO train

Who isn’t gunning for a biotech initial public offering these days? We thought that maybe after Moderna’s monster raise last year we had reached a peak, but the window remains open, and Trevi is the latest biotech to jump on through.

[Sponsored] The Power to Pivot: Using Dedicated Onsite Resources to Adapt Recruitment Practices in a Shifting Landscape

Increasingly complex trials place a burden on study sites, exacerbating already-troubling recruitment and enrollment issues. Strategically placed Enrollment Assistants can ease that burden, making sites more agile and offering patients personalized attention that leads to conversion and retention.

U.K. biotech Kymab nabs new CEO from Merck KGaA

Kymab has hired on a new CEO, Simon Sturge, to usher the antibody specialist into its next phase of growth. Sturge joins from Merck KGaA, where he oversaw the launches of cancer drugs Bavencio and Mavenclad for multiple sclerosis.

Allergan's failed depression drug shows promise in opioid withdrawal

Allergan's rapastinel, the centerpiece of its $560 million acquisition of Naurex, recently failed in pivotal trials in depression. But scientists at Duke University and Villanova University may have found another use for the drug: to aid in opioid withdrawal.

Pricing a hurdle for next-gen devices, but Canadian robotics company says change is coming

“The economic and mathematical model must be changed to analyze [payers’] involvement. ... But it will happen within some years, for sure. So we just need to survive until then,” said Stéphane Bédard, CEO of B-Temia, a Quebec City-based company developing what it calls dermoskeletic devices to assist human mobility.

Special Report—The top 15 pharma companies by 2018 revenue

The big names always turn up near the top of yearly sales rankings, and this year is no different. Many companies on this list have faced big patent losses in recent years, while some have big launches coming up, too.

Resources

[Whitepaper] Redefining Your Value to Win Empowered Patients: Six Steps to Success

Every life sciences firm talks about patient-centricity, but are you doing what it takes to deliver?

[Webinar] Doing Trials in Russia? Disrupt the market barriers through eClinical

How to cut a study budget by 4 times? How to process CRFs 3 times faster? What made a CRO switch from a US vendor to Data MATRIX? In 45 minutes, we will dissolve myths about entering the market.

[Whitepaper] Key Life Sciences Trends, 2019 and Beyond

The year’s biggest compliance and technology trends in life sciences. Learn about the latest trends impacting the biotech, medical device and pharmaceutical industries.

[Whitepaper] The New World of Allosteric Modulation: Another Shot on Goal

Learn how to utilize allosteric modulation to maximize its full potential in drug discovery programs. Download this white paper to learn more.

[Whitepaper] Advanced HDX-MS and Native-MS for Improved Biologic Candidate Selection and Development

Discussion of the potential for improving biologic drug development success through earlier, strategic application of advanced mass spectrometry, because currently, with most biologic drugs, including gene therapies, failures are realized in late-stage development, after substantial investment has been made in a candidate.

[Whitepaper] Workbench for Biomarker and Translational Research

Clinical trials and biomarker data from patients when unified, harmonized, and made searchable; is a rich, reliable and controlled resource for research. This paper sets out the requirements for a Translational and Biomarker Research Workbench for scientists using the experiences from use of Xbiom™ at BioPharma.

[Whitepaper] Meet Our Uncle: 12 Protein Stability Applications on One Platform

Download this whitepaper to learn more!

[Whitepaper] Flow Chemistry For Modern API Development & Manufacturing

Is Flow Chemistry right for your API Development?

[Whitepaper] Systolic Heart Failure: Real-World Study Using Electronic Health Records

Real-World case study by Veradigm suggests that new medications specifically approved for the treatment of systolic heart failure may be underutilized despite being important advances in patient care.

[Article] Are you ready for 2008 Microsoft SQL and Windows Servers end of life?

Software end of life puts you at risk for data breaches, business disruption and liability. Support for Microsoft SQL Server 2008/2008 R2 and Windows Server 2008/2008 R2 ends on July 9, 2019 and January 14, 2020, respectively. Learn how you can turn these risks into a strategic business advantage.

[Whitepaper] Better Market Intelligence With Smart Search

From new regulations to drug pricing and the latest M&A deals, learn how AI is making it easier for competitive intelligence to uncover the insights they need to stay ahead of the curve.

[Case Study] TriCore Reference Laboratories Transforms to Clinical Lab 2.0 Model

Analytics using patients’ real-time longitudinal laboratory results, and claims data, yielded higher value information and new revenue streams for TriCore reference laboratories.

[Whitepaper] Accelerating Clinical Trials through Access to Real-World Patient Data

Whitepaper on leveraging normalized real-world patient data to streamline clinical trials, reduce delays and lower costs.

[eBook] 2018 Weekly Compendium

The Biopharma industry is moving at lightning speed and it can be a challenge to keep pace. Here at Biotech Primer we spend hours each week researching, writing, and editing original content for the Biotech Primer WEEKLY with one goal in mind: to help everyone better understand the latest science and technology driving today’s healthcare industry.

Events