Medtronic TAVR shows benefits in women-focused trial

Today’s Big News

Apr 9, 2024

AACR: Detailed data spark glimmer of hope for Merck's Keytruda-Lynparza combo in lung cancer


Karuna's captains set sail in new neuropsychiatric venture called Seaport Therapeutics


ACC: Medtronic heart valve shows benefits in head-to-head TAVR study focused on women


AACR 24: AstraZeneca next-gen PARP inhibitor gives 'bang for your buck' over firstcomers


Amid corporate restructuring, Novartis plots 680 layoffs in development group

 

Featured

AACR: Detailed data spark glimmer of hope for Merck's Keytruda-Lynparza combo in lung cancer

In December, when Merck revealed that Lynparza didn't add benefits to Keytruda in certain non-small cell lung cancer patients, the trial appeared to be a complete failure. Although the study itself is beyond salvaging, detailed data now raise some hope for the combination in the future.
 

Top Stories

Karuna's captains set sail in new neuropsychiatric venture called Seaport Therapeutics

Just months after Bristol Myers Squibb boarded Karuna for its much-hyped schizophrenia drug, the biotech’s leadership has set sail in a new venture.

ACC: Medtronic heart valve shows benefits in head-to-head TAVR study focused on women

The largest randomized trial to compare Medtronic’s Evolut and Edwards’ Sapien TAVR implants is also the first to primarily focus on women.

AACR 24: AstraZeneca next-gen PARP inhibitor gives 'bang for your buck' over firstcomers

First-in-human results for AstraZeneca's saruparib showed an objective response rate of 48.8% in the 31 evaluable patients at the target dose. Median progression-free survival was 9.1 months.

Amid corporate restructuring, Novartis plots 680 layoffs in development group

Even as Novartis rolls ahead with a global restructuring campaign targeting thousands of job cuts, the Swiss drug giant has blueprinted several hundred layoffs in its development organizational unit.

#FierceMadness: The Best Biotech Name Tournament—A champion is CROWNED

What's the best biotech name? It's time to vote in the Fierce Madness #biotechbracket.

Bayer taps new North America marketing chief for consumer health division

In yet another C-suite shift for Bayer’s consumer health business, the division’s North America segment has appointed a new chief marketing officer.

MMI's Symani microsurgery robot secures de novo clearance from FDA

Hot on the heels of a $110 million fundraising round earlier this year, Medical Microinstruments has now received a groundbreaking green light from the FDA for its robotic surgery system.

Pfizer plots Abrysvo expansion with positive study in wide pool of adults at risk from RSV

As Pfizer races to grow the RSV vaccine market along with rival GSK, the company has been looking to expand its vaccine's reach. Now, with fresh data for Abrysvo in adults at higher risk of disease, the New York drugmaker is plotting a new approval filing.

AACR 24: Oncologists look to the skies as partial solar eclipse passes over San Diego

When a rare solar eclipse passes overhead, what’s a scientist to do, but stop and take a look?

Old MRI, new tricks: Q Bio puts forward quantifiable, reproducible scanning approach

Q Bio aims to have people reconsider the possibilities of an MRI machine, with an advance in computing that could one day enable new uses for the diagnostic imaging hardware.

As FDA weighs another myeloma endpoint for accelerated approvals, experts say timely access is at stake

At an FDA advisory committee meeting this Friday, two teams will present their studies examining the utility of minimal residue disease (MRD) as a potentially approvable endpoint in multiple myeloma. For this report, Fierce Pharma spoke with experts to learn about what's at stake, including the need to bring new treatments to patients earlier.

CG Life adds Toolhouse to portfolio, snapping up digital agency to double in size

CG Life has found what it is looking for in Toolhouse, inking a deal to buy the digital agency for the tools to chisel out the next chapter in its story.

Advanced therapy CDMO Ascend nabs Florida manufacturing site and team from ocular gene therapy outfit Beacon

Ascend, which bills itself as a “total solutions gene therapy development partner,” has picked up the manufacturing team and site of Beacon Therapeutics in Alachua, Florida. As part of the deal, Ascend has also agreed to a long-term partnership with Beacon to produce its ocular gene therapies for clinical and commercial use.
 
Fierce podcasts

Don’t miss an episode

The unrecognized threat of PAD

This week on “The Top Line,” join Editor-in-Chief of Fierce Life Sciences and Healthcare Ayla Ellison as she sits down with Kumar Madassery, M.D., Director of Peripheral Vascular Intervention & CLI Program at Rush University Medical Center, to explore peripheral arterial disease—a serious health issue that is often overlooked and undermanaged.
 

Resources

eBook

Discover the future of mAb manufacturing

Unlock the future of mAb manufacturing with our complete guide to integrating the revolutionary Gibco™ Efficient-Pro™ Medium and Feeds System, enhancing productivity and quality for exceptional outcomes 
Whitepaper

Oncology Market Outlook 2024

This paper assesses the current state of the oncology market, reviewing key expectations for 2024. It addresses CAR-T therapies, KRAS, radiopharmaceuticals, & targeted protein degradation.
Whitepaper

Guidance for Biotechs Choosing Next-Gen Contract GMP/CMC Labs

Choosing the right contract lab can help drug developers accelerate their timelines and generate cost-efficiencies. For insights into what to look for when selecting a GMP/CMC lab partner read this white paper which delves into a range of factors that can support your needs in both the short-term and in planning for the future.
 

Industry Events

Drug Development Boot Camp® VIRTUAL | Spring 2024

April ‌10-11, ‌2024

On Helix

Date: ‌4 ‌July ‌2024 ‌- ‌Location: ‌Babraham ‌Research ‌Campus, ‌Cambridge ‌UK

 

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