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April 12, 2019

Today's Rundown

Featured Story

Can adding Novo's GLP-1 to Gilead's NASH combo help hit fatty liver disease? New trial aims to find out

After announcing a small but broadly positive combo for its two biotech buyout NASH drugs yesterday, Gilead is hoping that adding a diabetes and obesity drug from Novo Nordisk can help boost its ability to knock out fat in the liver.

Top Stories

Unlocking small data, the ‘next frontier’ in drug discovery

“Ultimately, every drug discovery project starts off as a small-data project,” said Andrew Hopkins, Exscientia CEO. “And of course, that is where the commercial imperative is as well, to develop innovative medicines.”

Aurinia poaches CEO Peter Greenleaf from Cerecor

Peter Greenleaf arrives at Aurinia as it moves its drug, voclosporin, through phase 3 for lupus nephritis, a type of kidney inflammation related to lupus.

[Sponsored] The Power to Pivot: Using Dedicated Onsite Resources to Adapt Recruitment Practices in a Shifting Landscape

Increasingly complex trials place a burden on study sites, exacerbating already-troubling recruitment and enrollment issues. Strategically placed Enrollment Assistants can ease that burden, making sites more agile and offering patients personalized attention that leads to conversion and retention.

Ebola survivors' immune responses offer clues for vaccine development

Vaccines against the Ebola virus have been distributed amid several outbreaks. But the immune response to the virus is still not fully understood, which makes improving vaccine design a challenge. Now, scientists in France have found some clues to improving the vaccines by studying survivors from the 2014-2016 outbreak.

EuroBiotech Report—Bayer boosts U.S. research workforce, Poxel sees diabetes success and Kymab turns to Merck KGaA for next CEO

In this week's EuroBiotech Report, Bayer is planting seeds in Kendall Square, Poxel saw its shares jump, Kymab turns to former German Merck executive, J&J Vision and Edwards spend millions on new medtech manufacturing sites in Ireland and more.

FiercePharmaAsia—PD-1 royalty dispute; Takeda Latam asset sale; Chinese genomics investor in U.S.

Nobel laureate demands a bigger cut of Ono's Opdivo revenues; on a selloff spree, Takeda is said to be scouting bidders for its Latin American business; the Trump administration forces a Chinese genomics investor out of a U.S. health service platform; and more.

Chutes & Ladders—Shire R&D chief jumps ship to Ironwood spinout amid Takeda megamerger

Shire R&D chief jumps ship to Ironwood spinout amid Takeda megamerger; Daiichi taps new CEO as it unveils tie-up with AstraZeneca; and U.K. biotech Kymab nabs new CEO from Merck KGaA. Those moves plus more hirings, firings and retirings throughout the industry.

Resources

[Whitepaper] Redefining Your Value to Win Empowered Patients: Six Steps to Success

Every life sciences firm talks about patient-centricity, but are you doing what it takes to deliver?

[Webinar] Doing Trials in Russia? Disrupt the market barriers through eClinical

How to cut a study budget by 4 times? How to process CRFs 3 times faster? What made a CRO switch from a US vendor to Data MATRIX? In 45 minutes, we will dissolve myths about entering the market.

[Whitepaper] Key Life Sciences Trends, 2019 and Beyond

The year’s biggest compliance and technology trends in life sciences. Learn about the latest trends impacting the biotech, medical device and pharmaceutical industries.

[Whitepaper] The New World of Allosteric Modulation: Another Shot on Goal

Learn how to utilize allosteric modulation to maximize its full potential in drug discovery programs. Download this white paper to learn more.

[Whitepaper] Advanced HDX-MS and Native-MS for Improved Biologic Candidate Selection and Development

Discussion of the potential for improving biologic drug development success through earlier, strategic application of advanced mass spectrometry, because currently, with most biologic drugs, including gene therapies, failures are realized in late-stage development, after substantial investment has been made in a candidate.

[Whitepaper] Workbench for Biomarker and Translational Research

Clinical trials and biomarker data from patients when unified, harmonized, and made searchable; is a rich, reliable and controlled resource for research. This paper sets out the requirements for a Translational and Biomarker Research Workbench for scientists using the experiences from use of Xbiom™ at BioPharma.

[Whitepaper] Meet Our Uncle: 12 Protein Stability Applications on One Platform

Download this whitepaper to learn more!

[Whitepaper] Flow Chemistry For Modern API Development & Manufacturing

Is Flow Chemistry right for your API Development?

[Whitepaper] Systolic Heart Failure: Real-World Study Using Electronic Health Records

Real-World case study by Veradigm suggests that new medications specifically approved for the treatment of systolic heart failure may be underutilized despite being important advances in patient care.

[Article] Are you ready for 2008 Microsoft SQL and Windows Servers end of life?

Software end of life puts you at risk for data breaches, business disruption and liability. Support for Microsoft SQL Server 2008/2008 R2 and Windows Server 2008/2008 R2 ends on July 9, 2019 and January 14, 2020, respectively. Learn how you can turn these risks into a strategic business advantage.

[Whitepaper] Better Market Intelligence With Smart Search

From new regulations to drug pricing and the latest M&A deals, learn how AI is making it easier for competitive intelligence to uncover the insights they need to stay ahead of the curve.

[Case Study] TriCore Reference Laboratories Transforms to Clinical Lab 2.0 Model

Analytics using patients’ real-time longitudinal laboratory results, and claims data, yielded higher value information and new revenue streams for TriCore reference laboratories.

[Whitepaper] Accelerating Clinical Trials through Access to Real-World Patient Data

Whitepaper on leveraging normalized real-world patient data to streamline clinical trials, reduce delays and lower costs.

[eBook] 2018 Weekly Compendium

The Biopharma industry is moving at lightning speed and it can be a challenge to keep pace. Here at Biotech Primer we spend hours each week researching, writing, and editing original content for the Biotech Primer WEEKLY with one goal in mind: to help everyone better understand the latest science and technology driving today’s healthcare industry.

Events