To view this email as a web page, click here

   Home

Subscribe

Advertise

 

 

 

 

April 15, 2020___

Today's Rundown

Featured Story

Gilead shares slip as a 2nd remdesivir COVID-19 trial halted in China

After having to halt enrollment in its severe COVID-19 trial due to a lack of patients, a second test of Gilead’s old Ebola drug remdesivir has befallen the same fate, this time in patients with a milder form of the disease.

Top Stories

WHO tasks ex-GSK CEO Witty with hastening COVID-19 vaccine R&D

The World Health Organization (WHO) has tasked ex-GlaxoSmithKline CEO Andrew Witty with helping accelerate development of a COVID-19 vaccine. Witty is taking a leave of absence from his job at UnitedHealth Group until around the end of the year to co-lead the WHO initiative.

Lawrence lands Cardurion CEO job after helping ArQule to Merck buyout

Peter Lawrence has taken up the CEO job at Cardurion Pharmaceuticals, a Takeda-partnered biotech that is moving a heart failure drug through the clinic. Lawrence landed the gig on the strength of a 14-year spell at ArQule that culminated in a $2.7 billion takeover by Merck.

Moma Therapeutics aims at molecular machines with $86M raise

Moma Therapeutics wants to crack a new type of drug target wide open. The company snagged $86 million from the likes of Third Rock Ventures to systematically go after molecular machines, a family of more than 400 enzymes that others have only stumbled upon by chance.

Novartis, TScan unite on TCR treatments for solid tumors

Last summer, Novartis pitched in to a $48 million venture round for a cell therapy startup called TScan Therapeutics. Now, the Swiss pharma is back for more: In a deal worth $30 million upfront, the duo is on the hunt for targets that could lead to new T-cell receptor therapies for solid cancers.

Leo Pharma pens Oneness Biotech, Microbio Shanghai pact for skin and asthma drug

Leo Pharma is paying $40 million upfront and $530 million in biobucks to license a midstage experimental eczema and asthma drug.

Boehringer Ingelheim taps Insilico Medicine for AI drug target collaboration

Boehringer Ingelheim has tapped artificial intelligence maven Insilico Medicine to help identify new drug targets through its internal Research Beyond Borders initiative, which is tasked with forming new collaborations outside of the company’s traditional therapeutic areas and geographies.

Can a popular class of diabetes drugs that includes Merck's Januvia help treat COVID-19?

Scientists are attempting to repurpose existing drugs as a quick way to tackle COVID-19. Among them is a University of Miami researcher who has pointed to previous studies of other coronaviruses in suggesting DPP-4 inhibitors used to treat diabetes might help.

Resources

[GUIDE] Managing Clinical Trial Patient & Site Engagement During COVID-19

Leverage strategic solutions to respond to immediate challenges to patient and site engagement from COVID-19, and learn to maximize the FDA guidance on the conduct of clinical trials during a pandemic.

[Whitepaper] Navigating the Changing Clinical Trial Landscape

The research conducted here is to help understand and solve the top challenges in clinical operations, to remove barriers that are slowing down our ability to bring new drugs to market as quickly as possible to patients waiting in need.

[Whitepaper] Successful BYOD in Any Phase

This white paper includes a Phase III case study and discusses BYOD advantages and misconceptions, regulatory, copyright, and equivalency considerations.

[Whitepaper] A Fast Way to Curb Your R&D Spend: Make Failure a Strategy

Turn your drug failures into competitive advantage.

[Whitepaper] Payers’ Perspectives on Digital Therapeutics In-Depth Interviews Reveal What Manufacturers Can Expect

How will US payers evaluate and manage digital therapeutics? Get insights and recommendations on successful market access considerations.

[eBook] 9 Ways to Enhance Healthcare Customer Experiences

Download this e-book to learn 9 ways to enhance the customer experience within healthcare marketing.

[Whitepaper] Data Integration and the R&D Organization

Despite advances in content aggregation and search, silos still limit the free flow of data and analytics. So, what can be done, and how can you get more value from the data you already have?

[Webinar] Model-Based Approach to Design Bispecific Modalities in Early Discovery

Learn how we used a tiered model-based approach of a bispecific antibody to appropriately cover multiple antigen pairs to help teams with informed antibody design, prioritization of experiments, and triaging of challenging antigen pairs

[Whitepaper] Digital Twins: Creating Digital Operations Today to Deliver Business Value Tomorrow

This whitepaper highlights the challenges of implementing the right digital twin strategy while providing key use cases in the manufacturing domain for which a digital twin is extremely useful and several examples of technology trends that will shape the future.

[Guide] Pandemic Survival Guide --- IT Solutions for Business Continuity

To survive in these challenging conditions, companies need to promptly address business continuity issues - especially the remote delivery of data and voice solutions. See how Outer Edge can help.

[Whitepaper] Ensuring the Greatest Return From Your Poorly Soluble Molecule

Poorly soluble molecules hindering your workflow?

[On Demand] Tufts-eClinical Solutions Data & Analytics Survey Results

Key findings from the 2019 Life Sciences Data & Analytics Survey conducted by the Tufts Center for the Study of Drug Development will be unveiled during this live webinar led by industry expert and study lead, Ken Getz, Director of Sponsored Programs and Associate Professor.

[eBook] Expecting the Unexpected: Strategies for Efficient Clinical Supply Management and Forecasting

Learn how to drive excellence within the forecasting process and utilize forecasting throughout the clinical study to better plan clinical supply budgets and project timelines. Explore how to identify potential supply-related issues before they can negatively impact your study.

[Fact Sheet] Forecasting to Optimize Clinical Trial Supply Management

Whether a study is simple or highly complex, forecasting and simulation reports serve as data driven communication tools to help minimize risks and keep the study on track. Learn more about forecasting solutions for informed decision making and supporting contingency planning for clinical study.

[Case Study] Establishing Parameters for Success

Learn about a real-world example of how clinical supply management expertise was applied to overcome inventory challenges for a complex, global study.

[Executive Summary] Strategies for Flexible Manufacturing

This whitepaper discusses the benefits of end-to-end solutions and share case studies on how flexible manufacturing strategies can accommodate the changing landscape of pharmaceutical products and help bring a drug to market.

[Presentation] Flexible Manufacturing Strategies

Get expert insights on strategies to implement flexible manufacturing and different technologies that are easily scalable and reproducible.

[Executive Summary] Overcoming Manufacturing Challenges for Accelerated Drug Development

Regardless of the assigned FDA expedited approval designation and approach, the key action items should be: the assurance of a detail-oriented plan and the adaption of a “forward-thinking” approach that will assist in any future challenges and opportunities for growth of each project.

[Case Study] Precision Analytics for Product Launch and Growth

Pharma launch teams spend significant resources on data and analytics with limited ROI. Read this case study to learn how a Life Sciences company identified two times more patients best suited for therapy, using Clarify’s deep and longitudinal patient and HCP insights. 

Events