Plus biotech's top 10 money raisers
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WELCOME TO FIERCE LIFE SCIENCES WEEKLY DIGEST

After 2020 set records for private biotechs’ ability to raise cash, 2021 shattered them once again—by a whopping 26%, for a total of $28.5 billion changing hands. But while the figures can be eye-watering, they become less rosy as you dig deeper. Despite some gargantuan fundraisings, the number of rounds and the number of dollars raised decreased each quarter after starting the year with a bang. Our list of biotech’s top 10 money raisers, plus the top stories of this week, follow below.

Featured Story

Game over: Bristol Myers, Nektar end $3.6B immuno-oncology program after 2 more late-stage flops

Bristol Myers Squibb and Nektar have read the last rites to their huge, failed cancer collaboration. With two more late-stage trials failing, the partners have ended clinical development of a combination they once saw as the future of immuno-oncology.

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Top Stories Of The Week

Gilead, after setbacks, aims to pull a third of its revenue from oncology business by 2030

In its Oncology Deep Dive presentation last week, Gilead said it plans to derive a third of its revenue from oncology products by 2030. That will require a major transformation as the company made less than $2 billion of its $27 billion in sales from cancer products in 2021.

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Biotech's top 10 money raisers of 2021

2021 marked the second consecutive year of record-breaking private financing for biotechs, with more than $28 billion raised. The total haul is a 26% increase from 2020, and the stunning dollar amounts came even as the public market depreciated throughout the year. Here's our look at the 10 biotechs that raked in the largest VC investments.

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Novavax, fashionably late to the COVID-19 vaccine party, could still reap $5B in 2022: analyst

After a winding path to a coronavirus vaccine launch that still hasn’t reached the U.S., Novavax's program could be destined to reap billions of dollars in sales this year, one group of analysts predicts.

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UPDATE: TG disbands cancer program after pulling FDA request for U2 combo therapy

TG Therapeutics is winding down its oncology program after removing the FDA-approved cancer med Ukoniq from the market in two indications that were granted accelerated approval in addition to withdrawing an approval request for a combo med dubbed U2. 

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Pfizer's COVID-19 antiviral Paxlovid hits worldwide demand slump: report

Despite high expectations, Pfizer's COVID-19 antiviral Paxlovid has encountered relatively low demand worldwide lately, Reuters reports. Pfizer is expecting more than $20 billion in sales from the treatment this year.

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Novavax touts early data for flu-COVID combo vaccine as FDA decision looms for single shot

Novavax touted early data of its combo vaccine for the flu and COVID-19, saying the shot elicited an immune response comparable to standalone flu and COVID shots. The results come as the company is still awaiting a decision from the FDA on its EUA submission for its COVID jab.

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Philips piles on another trio of Class I recalls for beleaguered ventilator portfolio

There seems to be no limit to Philips’ ventilator safety woes. Nearly a full year after initiating a recall of 5.2 million respiratory devices, the company continues to accumulate safety notices for those and other devices in its vast respiratory portfolio.

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Pharmas risk losing doctors to digital fatigue in the post-COVID-19 world if they don't get their email strategy right

Healthcare professionals want high quality, low quantity and good structure when it comes to email campaigns. If they fail to get this balance right, pharma marketers risk entrenching so-called “digital fatigue” from doctors as the world comes out of the pandemic.

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Gilead targets 400 jobs, assembles cell therapy manufacturing troika with FDA nod for Maryland site

Gilead Sciences’ Kite Pharma has further beefed up its cell therapy manufacturing footprint as a recent FDA approval for Yescarta promises to increase demand.

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New blood stem cell road map helps scientists learn from mistakes on quest to create cells in lab

Researchers at UCLA have unveiled a novel road map tracking blood stem cell development in the human embryo, findings that could help develop new treatments for blood cancers and inherited blood disorders.

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Resources

Research: Healthcare Has No Borders: The Role of Rescue Sites in Times of Global Calamity

More than 570 clinical trials in Ukraine have been disrupted. Unanticipated disruptions to medical testing and clinical trials impede progress toward new breakthroughs and new therapies that millions of patients around the world hang their hope on. What role do rescue sites play?

Infographic: United Cargo: Providing Comprehensive Solutions For the Most Critical Shipments

The United Cargo team has made a commitment to pharmaceutical and medical partners that we are equipped to support their vaccine transportation needs safely and effectively across our expansive global and domestic network. The safety and security of these commodities is our priority, and we are proud to be a trusted partner in these efforts. Download infographic now.

Whitepaper: Oncology Market Outlook: Key Trends to Watch

What’s in store for the oncology market in 2022 and beyond? This paper looks at 5 trends driving the market.

Whitepaper: Uncovering the hidden value of quality in chemical supply

Learn how to position quality as a central component within your raw material sourcing strategies for the chemicals used throughout your workflows. Download the free whitepaper from Thermo Fisher Scientific.

Events