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April 23, 2019

Today's Rundown

Featured Story

Biotechs getting bigger in late-stage R&D, leaving Big Pharmas behind: report

The biotech industry is becoming the most active group for later-stage pipeline work, and while Big Pharma sees its R&D share drop, emerging life science companies are better prepared to go it alone.

Top Stories

Fulcrum bags failed GSK drug, plots muscle-wasting pivot

GlaxoSmithKline has offloaded the global rights to failed cardiovascular disease drug losmapimod to Fulcrum Therapeutics. Fulcrum plans to reposition the p38 mitogen-activated protein kinase inhibitor as a treatment for facioscapulohumeral muscular dystrophy.

Genentech backs U.K. accelerator to help pre-A round startups

Genentech has backed Cambridge, U.K.-based life science accelerator Start Codon. The money will enable Start Codon to provide startups with the funding, lab space and support they need to get to a series A fundraise.

[Sponsored] Using the Innate Immune System to Treat Disease

Reprogramming the innate immune system, rather than the adaptive immune system, may be the path to treat both cancer and Alzheimer’s disease.

Pfizer oncology executive hops over to Aduro as its new chief medical officer

Aduro Biotech has a new chief medical officer: Dimitry Nuyten, M.D., Ph.D., who joins as the company is refocusing on cancer drugs targeting the STING and APRIL pathways.

Bioclinica wants to move the needle in NASH

Biotech and pharma companies shared their mid- to late-stage fatty liver disease data earlier this month at the EASL liver conference, and now the first-ever approval addressing this growing health burden appears to be peeking over the horizon.

Resources

[Whitepaper] Personalized Test for Treatment Prediction in Depression

Total Brain Announces Personalized Test for Treatment Prediction in Depression with 80% Accuracy.

[Whitepaper] Observed Impact of Medication Price Transparency on Patients and Practices

Prescription price transparency technology is here – but is it making a difference? Find out HERE.

[Whitepaper] Redefining Your Value to Win Empowered Patients: Six Steps to Success

Every life sciences firm talks about patient-centricity, but are you doing what it takes to deliver?

[Whitepaper] Key Life Sciences Trends, 2019 and Beyond

The year’s biggest compliance and technology trends in life sciences. Learn about the latest trends impacting the biotech, medical device and pharmaceutical industries.

[Whitepaper] The New World of Allosteric Modulation: Another Shot on Goal

Learn how to utilize allosteric modulation to maximize its full potential in drug discovery programs. Download this white paper to learn more.

[Whitepaper] Advanced HDX-MS and Native-MS for Improved Biologic Candidate Selection and Development

Discussion of the potential for improving biologic drug development success through earlier, strategic application of advanced mass spectrometry, because currently, with most biologic drugs, including gene therapies, failures are realized in late-stage development, after substantial investment has been made in a candidate.

[Whitepaper] Workbench for Biomarker and Translational Research

Clinical trials and biomarker data from patients when unified, harmonized, and made searchable; is a rich, reliable and controlled resource for research. This paper sets out the requirements for a Translational and Biomarker Research Workbench for scientists using the experiences from use of Xbiom™ at BioPharma.

[Whitepaper] Meet Our Uncle: 12 Protein Stability Applications on One Platform

Download this whitepaper to learn more!

[Whitepaper] Flow Chemistry For Modern API Development & Manufacturing

Is Flow Chemistry right for your API Development?

[Whitepaper] Systolic Heart Failure: Real-World Study Using Electronic Health Records

Real-World case study by Veradigm suggests that new medications specifically approved for the treatment of systolic heart failure may be underutilized despite being important advances in patient care.

[Article] Are you ready for 2008 Microsoft SQL and Windows Servers end of life?

Software end of life puts you at risk for data breaches, business disruption and liability. Support for Microsoft SQL Server 2008/2008 R2 and Windows Server 2008/2008 R2 ends on July 9, 2019 and January 14, 2020, respectively. Learn how you can turn these risks into a strategic business advantage.

[Whitepaper] Better Market Intelligence With Smart Search

From new regulations to drug pricing and the latest M&A deals, learn how AI is making it easier for competitive intelligence to uncover the insights they need to stay ahead of the curve.

[eBook] 2018 Weekly Compendium

The Biopharma industry is moving at lightning speed and it can be a challenge to keep pace. Here at Biotech Primer we spend hours each week researching, writing, and editing original content for the Biotech Primer WEEKLY with one goal in mind: to help everyone better understand the latest science and technology driving today’s healthcare industry.

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