Sio asset-less after ditching UMass collab
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Today's Rundown

Catalent Trending Topic: Cell & Gene Therapy
Read on to understand how the industry is addressing gene therapy and cell therapy research and development.

Featured Story

SURMOUNT-able: Lilly's tirzepatide clears high bar set by Novo's Wegovy in obesity

The unstoppable march of Eli Lilly’s tirzepatide continues. Having previously shown the dual GIP/GLP-1 agonist reduces the weight of people with diabetes, Lilly has now delivered a hit in its first phase 3 pure play obesity trial, putting Novo Nordisk’s Wegovy on notice that a serious challenger may be on the horizon.

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Top Stories

Pfizer's phase 3 DMD gene therapy test resumes after FDA hold, but decision on advanced patients still pending

Pfizer is getting back to work on a late-stage test for its Duchenne muscular dystrophy gene therapy. The decision comes several months after a patient death in a phase 1 trial drew a clinical hold on the medicine from the FDA.

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Sio Gene Therapies warns of 'significant' layoffs after ditching final two assets

Sio Gene Therapies is now without a product after ending clinical development of its last two assets, prompting the company to seek an emergency exit and warn of impending layoffs.

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Sponsored: Using Knowledge Graphs to Drive Drug Discovery

Biomedical knowledge graphs can power many different application in drug discovery. Learn which key feature you should look for and why.

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After Amgen deal, Plexium maintains momentum with AbbVie neurological partnership

Riding high after an Amgen partnership and a $102 million funding round so far this year, Plexium shows no signs of slowing down. Instead, it's inked a new agreement with AbbVie focused on neurological conditions.

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GV, Sanofi drive British biotech OMass to $100M series B, fueling work on undruggable targets

GV, Northpond Ventures and Sanofi Ventures have joined forces to pump $100 million into OMass Therapeutics, teeing the British biotech up to advance candidates against hard-to-hit targets toward the clinic. 

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Lipids that wind down inflammation could be a critical therapeutic tool for MS

New research from an international team of scientists found that a specific kind of lipid associated with winding down the inflammation could be a boost in treating multiple sclerosis. A new study found administering the lipid reduced pro-inflammatory proteins and immune cells.

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BioMarin posts record quarterly sales as Voxzogo launch heats up

BioMarin tallied record quarterly revenues of $519 million in the first three months of 2022, with new achondroplasia med Voxzogo chipping in $20 million.

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Amgen vows to fight $7.1B tax bill tied to Puerto Rico manufacturing unit

When Amgen released first-quarter results on Wednesday, its sales and profit numbers were again overshadowed by a bombshell tax disclosure.

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Sanofi's Dupixent puts on another stellar show, and it's still 'at the beginning' of the journey: exec

Five years after its first FDA approval in eczema, Sanofi's Dupixent is still blazing a trail in inflammatory diseases. That's the evaluation of Sanofi's global head of specialty care after the drug's sales shot up 46% in the first quarter of 2022.

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Resources

Research: Healthcare Has No Borders: The Role of Rescue Sites in Times of Global Calamity

More than 570 clinical trials in Ukraine have been disrupted. Unanticipated disruptions to medical testing and clinical trials impede progress toward new breakthroughs and new therapies that millions of patients around the world hang their hope on. What role do rescue sites play?

Infographic: United Cargo: Providing Comprehensive Solutions For the Most Critical Shipments

The United Cargo team has made a commitment to pharmaceutical and medical partners that we are equipped to support their vaccine transportation needs safely and effectively across our expansive global and domestic network. The safety and security of these commodities is our priority, and we are proud to be a trusted partner in these efforts. Download infographic now.

Research: Get Access to AdisInsight A Year In Review

The journey of drug development in 2021 delivered to your inbox: top 10 AdisInsight drug profiles viewed, new drug profiles released, overview of drug launches, key deals, research trends in 2021 and much more (free of charge).

Whitepaper: Oncology Market Outlook: Key Trends to Watch

What’s in store for the oncology market in 2022 and beyond? This paper looks at 5 trends driving the market.

Whitepaper: Uncovering the hidden value of quality in chemical supply

Learn how to position quality as a central component within your raw material sourcing strategies for the chemicals used throughout your workflows. Download the free whitepaper from Thermo Fisher Scientific.

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