Harmony snaps up epilepsy biotech

Today’s Big News

Apr 30, 2024

Novartis pays PeptiDream $180M as radiopharma big bang continues


Newron's schizophrenia add-on improves symptoms, charging up case for phase 3 test


Sweet Harmony: Neuro biotech buys Epygenix and its epilepsy meds for $35M upfront


Despite trial miss, NRx pushes antidepressant forward with blockbuster hopes in bipolar depression


FDA wants to hear from you on future of advisory committee meetings


Annovis' shares plummet 60% on another failure for lead Alzheimer's med


How gut enzymes could make universal donor blood possible


Fierce Biotech Fundraising Tracker '24: Xaira raises $1B; Enlaza's $100M start

The Top Line Podcast: Don’t miss out on the newest episode. Listen now.

 

Featured

Novartis pays PeptiDream $180M as radiopharma big bang continues

Novartis is pumping another $180 million into its radioligand plan, handing the cash to serial dealmaker PeptiDream to expand a peptide-drug conjugate collaboration.
 

Top Stories

Newron's schizophrenia add-on improves symptoms, charging up case for phase 3 test

Newron Pharmaceuticals’ add-on schizophrenia treatment improved both positive and negative symptoms as well as severity in patients with the disorder during a phase 2/3 study.

Sweet Harmony: Neuro biotech buys Epygenix and its epilepsy meds for $35M upfront

Harmony Biosciences is spending $35 million upfront to buy Epygenix and its epilepsy meds. It's the neuroscience biotech's second deal in less than a month after it bought an orexin-2 inhibitor from Bioproject.

Despite trial miss, NRx pushes antidepressant forward with blockbuster hopes in bipolar depression

NRx Pharmaceuticals’ investigational antidepressant has failed to reach statistical significance in reducing depression severity in a phase 2/3 trial, though the biotech is pressing forward to a registrational study with the belief that the candidate could eventually become a “paradigm-changing blockbuster drug.”

FDA wants to hear from you on future of advisory committee meetings

The U.S. FDA is planning to hold an advisory committee meeting on…well, advisory committee meetings.

Annovis' shares plummet 60% on another failure for lead Alzheimer's med

Annovis Bio heralded a “significantly higher rate of improvement” in patients with Alzheimer’s disease who received buntanetap, however digging a little deeper into the muddled readout suggests the trial was a failure.

How gut enzymes could make universal donor blood possible

Finally, some bloody good news: Researchers have identified new enzymes that bring science closer to developing universal donor blood. In an article in Nature Microbiology, a team of researchers from the Technical University of Denmark and Lund University detailed how they discovered gut bacteria enzymes that remove not only A and B antigens from red blood cells but also other components that have historically hampered progress toward universal donor blood.

Fierce Biotech Fundraising Tracker '24: Xaira raises $1B; Enlaza's $100M start

Welcome to Fierce Biotech's Fundraising Tracker, 2024's version.

Walmart shuttering all 51 health centers, citing lack of profitability

Walmart is shuttering all 51 health centers along with its virtual care services, the retail giant announced Tuesday morning.

Eli Lilly’s growth drivers, Verzenio and Jardiance, suffer clinical setbacks

Besides the diabetes and obesity duo of Mounjaro and Zepbound, the SGLT2 inhibitor Jardiance and the CDK4/6 cancer drug Verzenio were cited as the main growth drivers for Eli Lilly’s first quarter. But both meds had some bad news to report from late-stage clinical trials.

Philips signs $1.1B settlement in CPAP recall injury litigation, takes $578M insurance payout

Philips has reached a $1.1 billion agreement to settle claims from about 58,000 people stemming from its yearslong recall of home CPAP ventilators and sleep apnea machines.

Here's what 'fair allocation' for GLP-1s and other weight loss drugs could look like

A new study aims to establish an ethical framework that can be used to ensure the patients who need these therapies can access them amid shortages.
 
Fierce podcasts

Don’t miss an episode

'The Top Line': A look at pharma revenue rankings

This week on "The Top Line," Fierce Pharma Senior Editor Eric Sagonowsky and Senior Writer Kevin Dunleavy are diving into our annual top pharma companies by revenue special report.
 

Resources

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Branded Digital Companions in Biopharma

This paper defines “digital companions” in biopharma, explores their value from the patient & company perspectives, & outlines a process for successfully fielding a new digital companion.
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Vaccine Development Challenges in Facing Influenza and COVID-19

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Antibody Profiling: Decoding the Humoral Immune System

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Straight to Market in an Autoinjector

The use of prefilled syringes to administer biotherapeutics is beginning to gain traction because they offer a range of stability, efficacy, and patient safety benefits. Download this white paper to learn how Lonza has developed a novel workflow to ensure confidence regarding functionality in PFS and autoinjectors.
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Discover the future of mAb manufacturing

Unlock the future of monoclonal antibody (mAb) manufacturing with a complete guide to enhancing productivity and quality for exceptional outcomes.
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Oncology Market Outlook 2024

This paper assesses the current state of the oncology market, reviewing key expectations for 2024. It addresses CAR-T therapies, KRAS, radiopharmaceuticals, & targeted protein degradation.

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Guidance for Biotechs Choosing Next-Gen Contract GMP/CMC Labs

Choosing the right contract lab can help drug developers accelerate their timelines and generate cost-efficiencies. For insights into what to look for when selecting a GMP/CMC lab partner read this white paper which delves into a range of factors that can support your needs in both the short-term and in planning for the future.
 

Industry Events

Drug Development Boot Camp® VIRTUAL | Spring 2024

April ‌10-11, ‌2024

On Helix

Date: ‌4 ‌July ‌2024 ‌- ‌Location: ‌Babraham ‌Research ‌Campus, ‌Cambridge ‌UK

 

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