Philips shareholders send warning to execs

Today's Big News

May 11, 2023

Next-gen Lilly obesity drug slashes weight in Innovent study—but is it enough to rival Mounjaro? 


Mirati's KRAS drug beats estimates in first quarter, but Keytruda combo plan remains unclear 


Philips shareholders vote against freeing execs from legal liability over 2022's troubles 


Otsuka, Lundbeck's antipsychotic Rexulti nabs new use in Alzheimer's disease agitation 


NYBC Ventures launches with $50M for blood and cell therapies 


We want your stories: Biopharma's collective memory of COVID—in photographs

 

Featured

Next-gen Lilly obesity drug slashes weight in Innovent study—but is it enough to rival Mounjaro?

Innovent Biologics has strengthened its pitch for the Chinese obesity market with fresh phase 2 data. The update shows giving mazdutide, a molecule from Eli Lilly’s deep bench of obesity assets, at a higher dose dialed up the placebo-adjusted weight loss to 15.4% after 24 weeks.
 

Top Stories

Mirati's KRAS drug beats estimates in Q1, but Keytruda combo plan remains unclear

Mirati Therapeutics' new KRAS cancer drug Krazati surprised analysts in its first full quarter on the market. But investors remain more interested in the company's plan for newly diagnosed lung cancer patients.

Philips shareholders vote against freeing execs from legal liability over 2022's troubles

After watching Philips’ valuation plummet more than 60% since the onset of the June 2021 recall of millions of its respiratory devices, shareholders aren’t letting the losses slide.

Otsuka, Lundbeck's Rexulti nabs new use in Alzheimer's disease agitation

Otsuka and Lundbeck's atypical antipsychotic Rexulti is now the first drug in the U.S. to treat Alzheimer's disease related agitation. This new use follows prior approvals in schizophrenia and major depressive disorder.

NYBC Ventures launches with $50M for blood and cell therapies

NYBC Ventures has unveiled as one of the first venture funds to focus solely on advancing new blood and cell-based therapies, with $50 million in hand from the New York Blood Center.

We want your stories: Biopharma's collective memory of COVID—in photographs

Fierce Pharma is asking you, the dedicated employees working in the biopharma industry, to tell your stories of the pandemic—in photographs.

BioNTech swiftly axes oral mRNA vaccine project after tech flunks early test

BioNTech has swiftly rejected an oral mRNA delivery technology. Barely one year after signing up to work with Matinas BioPharma, BioNTech found an initial mouse study failed to show preclinical activity—leading it to join Gilead on the list of companies to dump the biotech in recent months.

Bernie Sanders-led Senate committee takes pharma and PBMs to task—even after insulin price cuts

Even after top diabetes players Eli Lilly, Novo Nordisk and Sanofi slashed their insulin prices earlier this year, the companies still aren't off the hook. The CEOs of the companies—along with three PBM execs—faced intense questioning at a Bernie Sanders-led Senate committee hearing on insulin affordability.

Takeda cuts 2 midstage GI assets including Crohn's hopeful in latest pipeline cleanup

Takeda may have caught attention recently for ending work on its early-stage gene therapy R&D, but a close reading of the Japanese pharma’s latest earnings report reveals it has also culled a couple of gastrointestinal assets.
 
Fierce podcasts

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'Podnosis': The rise of digital therapeutics, and ways to fix the PBM industry

This week on "Podnosis," we discuss the rise of digital therapeutics and remaining barriers to implementation. We also talk about what it takes to fix the PBM industry.
 

Resources

Whitepaper

ChatGPT in Drug Discovery: Rise of Large Language Models

ChatGPT shows promise in drug discovery for information extraction, scientific text authoring, hypothesis prediction, and chemical entity prediction. This whitepaper explores its potential to streamline research, delving into its technology, applications, and limitations.
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Discovering High-Affinity, Functional Anti-GLP-1R Antibodies

Learn how a GPCR-focused library with a cell-based biopanning strategy led to the discovery of 13 high-affinity and selective anti-GLP-1R antibodies with highly developable therapeutic properties.
eBook

Decentralized Clinical Trials: The Complete Guide for 2023

Discover a game-changing approach to clinical research with Hybrid and Decentralized Clinical Trials (DCTs). Learn about the benefits, challenges, and key elements for success.
Research

How Lilly’s Legal and Library Services Empower Teams Across the Drug Development Pipeline

What role do the Library and Legal teams play in the drug development pipeline at Lilly? An import one – find out how.
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Medical Affairs Metamorphosis VI: The Changing Face of Stakeholder Engagement

This paper focuses on stakeholder engagement and how Medical Affairs teams’ responsibilities, goals, tools, and techniques are changing.
Research

Maximizing Clinical Trial Success

Strategies for Optimal Site Selection and Feasibility Research in Novel Therapies and Geographies
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eConsent: Flexible Consent Through Enabling Technologies

How can eConsent provide a more flexible approach to informed consent?
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Plan for scalable process liquid and buffer preparation

Preparation of critical process liquids and buffer components shifts resources away from core activities and can be filled with inefficiencies and risks that can increase time and costs across your workflow. Learn about the framework to help reduce your total costs beyond capital and operational expenditures and set a solid foundation for successful scale-up of buffer preparation.
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Running Decentralized Trials at Scale

Explore how clinical supply can be scaled up as decentralized programs progress, and how technological solutions can accelerate trial deployment.
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Designing an Optimal APAC Clinical Supply Chain

Discover key considerations that every trial sponsor should know when navigating the complex clinical supply distribution landscape across Asia-Pacific.
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Key Clinical Supply Issues Sponsors Should Consider with their CRO

As sponsors increasingly look to CROs to support their clinical studies, making and addressing certain clinical supply considerations at the outset of the relationship can reduce the risk of potentially unforeseen impact to budget and time later. Discover key issues sponsors should consider to help their CRO or partner of choice better understand their clinical supply needs.

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Specialized Expertise for Management of Clinical Supply Budgets

For sponsors, cost is a key concern when it comes to managing the supply of their clinical trials. A financial project analyst (FPA) is a specialized expert who can help control clinical supply costs and keep the project within budget. Explore the critical role that a Financial Project Analyst plays in clinical trial supply and budget management.
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Clinical Supply Solutions for the Asia-Pacific Region

Learn how Catalent’s extensive network across APAC can meet a wide range of clinical supply needs for sponsors conducting trials within the region.
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Roles and Responsibilities of Specialized Clinical Supply Experts

How can specialized expertise help you optimize your clinical supply chain? Learn about the roles and responsibilities of unique experts such as clinical supply management, project management, and financial project analysis.
Whitepaper

Questions You Need to Ask Your CRO About Clinical Supply

Planning on using a CRO to support your next clinical study? This infographic outlines critical areas to address at the start of the relationship in order to ensure that budget and timelines keep on track for the duration of the trial.
Whitepaper

Supply Services to Support Clinical Trials in Japan & Beyond

Explore Catalent’s newest clinical supply facility in Japan, including the comprehensive services & solutions it offers to help support trials both in-country & around the world.
 

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