Biohaven CEO hopes to strike gold twice
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WELCOME TO FIERCE LIFE SCIENCES WEEKLY DIGEST

Without groundbreaking science, it’s certain the biopharma industry wouldn’t be a trillion-dollar enterprise. In the second entry of its four-part series, Fierce Pharma looks at this year's most influential scientists and their impacts on the field. Meanwhile, Fierce Biotech looks at the executives tasked with putting those findings into practice—and the most well-compensated among them. Last year saw tectonic shifts in pay among R&D leaders, with reductions for some and boosts for others, bringing some newcomers to the top 10. Those special reports plus our top stories of the week follow below.

Featured Story

Most influential people in biopharma—the scientists

Without science, biopharma wouldn't exist. Without new, groundbreaking science, it might exist, but it wouldn't be very exciting—and it certainly wouldn't be a trillion-dollar enterprise. That's why our look at this year's most influential people had to turn to scientists next.

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Top Stories Of The Week

The top 10 highest paid biopharma R&D executives in 2021

The top 10 list of the highest-paid biopharma R&D execs looks a little bit different in 2021 than the year before after a number of pendulum swings in pay. And the new top 2 earners have since left their top research posts for CEO roles elsewhere.

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Moderna's new CFO out the door after former employer discloses accounting probe

Only a month after mRNA giant Moderna unveiled a CFO switch, its new finance chief is out the door because his former employer disclosed an internal accounting probe. As a result, Moderna is bringing back its former finance chief David Meline to run its books.

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After layoffs, BridgeBio turns to dealmaking for up to 6 drugs

After two recent layoff rounds, BridgeBio Pharma is looking to out-license six of its candidates to save capital. The biotech has been hit by the burden of the bear market after disclosing disappointing phase 3 results last year.

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Seagen CEO’s arrest came during a hazy night of booze, sex and alleged violence: police report

A police report of the domestic abuse arrest of Seagen CEO Clay Siegall, Ph.D., describes a drunken night involving him, his wife and another couple and includes sexual escapades and alleged violence that led Siegall to be taken to jail.

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Welcome to new (Bio) Haven: CEO hopes to strike gold twice with remaining R&D crew after Pfizer deal

After selling its potential blockbuster migraine program to Pfizer, Biohaven is hoping to strike gold twice. Its immediate future rests with two looming phase 3 readouts, the first of which is due in a few weeks.

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AstraZeneca, GSK's cancer rival Clovis quietly unveils crippling FDA delay as its troubles deepen

Declining sales of its lead cancer drug, a need to raise additional capital and a 30% stock price plunge depict the nightmare Clovis Oncology is living through right now. But that’s not all.

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UPDATE: VistaGen says regulators couldn’t sniff out abuse potential of its nasal spray for social anxiety

Regulators gave VistaGen the green light to continue developing its nasal spray to treat social anxiety without an additional trial to measure its abuse risks. VistaGen is expecting data from its first phase 3 trial in the coming weeks.

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Emergent destroyed up to 400M COVID-19 vaccines, far more than previously known: report

Emergent BioSolutions' COVID-19 vaccine manufacturing woes were well documented in 2021, but a new congressional probe found that the company's problems went much further than realized.

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Scientists may have inadvertently discovered how to reverse a central protein pitfall that causes dementia

A global team of scientists may have inadvertently discovered a potential treatment for one of the root causes of dementia. The researchers say when under stress, the endoplasmic reticulum actually reversed the build-up of protein "aggregates" caused by misfolding, a mechanism that can result in neurodegenerative diseases.

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Bristol Myers Squibb goes all out on unbranded campaigns for newly approved $13B drug Camzyos

Bristol Myers Squibb launched two education campaigns for the condition its new heart drug Camzyos treats, with Utah Jazz player Jared Butler headlining. The aim? Increase diagnosis of obstructive hypertrophic cardiomyopathy, a disease that until now has had no specific treatments.

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FDA clears its first in vitro test for the early detection of Alzheimer's disease

The FDA said the Lumipulse test developed by Fujirebio Diagnostics could allow some patients to skip PET brain scans for finding amyloid plaques.

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'The Top Line' podcast: Big Pharma's M&A lull, the shake-up in top 10 highest paid R&D execs, plus this week's headlines

This week on "The Top Line," we talk about why Big Pharma is resisting the temptation to go on a biotech M&A spree. We also discuss the 10 biggest earners among R&D chiefs and the drastic changes from last year's list, plus the week's biggest headlines.

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Resources

Executive Summary: PBPK Modelling for Optimizing Controlled Release Dosage Form Development

In this executive summary, we describe the benefits of controlled release, look at how to determine whether a drug is suitable for controlled release, review the application of PBPK modelling in controlled release formulation development and discuss how modified release products can be developed to deliver optimal patient outcomes.

Whitepaper: Gain Operational Speed and Velocity by Sharing Quality Incident Data

Quality operations guide your organization through regulatory compliance processes and safeguard your products, processes, and reputation. But your team is capable of so much more. Quality incident data and processes can be a driver of significant business value if shared with other stakeholders.

Whitepaper: Medical Affairs Metamorphosis: Trends Driving Change & What They Mean

Recent trends are driving big changes in Medical Affairs. This paper explores why, and what MA teams can do to stay ahead of the curve.

eBook: Streamline HCP interactions management

Don’t miss these critical considerations when evaluating your HCP interactions management program.

Research: Healthcare Has No Borders: The Role of Rescue Sites in Times of Global Calamity

More than 570 clinical trials in Ukraine have been disrupted. Unanticipated disruptions to medical testing and clinical trials impede progress toward new breakthroughs and new therapies that millions of patients around the world hang their hope on. What role do rescue sites play?

Infographic: United Cargo: Providing Comprehensive Solutions For the Most Critical Shipments

The United Cargo team has made a commitment to pharmaceutical and medical partners that we are equipped to support their vaccine transportation needs safely and effectively across our expansive global and domestic network. The safety and security of these commodities is our priority, and we are proud to be a trusted partner in these efforts. Download infographic now.

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