NRx tanks on ACTIV COVID failure
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Today's Rundown

Featured Story

With the right partner, Pfizer gains fast-track tag for previously shelved NASH drug

In a rare win for the difficult field of nonalcoholic steatohepatitis, Pfizer has been granted a fast-track ticket for two experimental therapies.

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Sponsored: Agilex Biolabs Doubles in Size with Launch of New Large Molecule Facility as It Expands Its U.S. Presence

Bioanalytical Laboratory Offers Qualified U.S. Clients a 43.5% Cash Rebate for Conducting Studies in its Australia-based FDA-Inspected Labs

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Top Stories

BridgeBio's CEO on staying alive, 'motherhood and apple pie'

It’s survival of the fittest, and BridgeBio Pharma is cutting fat—shedding any and all extra costs in an attempts to stay afloat in a prolonged bear market. CEO Neil Kumar, Ph.D., hopes the industry will take notes to ultimately embolden a better biotech frontier. 

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IN-ACTIV: NRx tanks as peptide fails NIH trial in severe COVID-19 patients

There goes another one. After a who’s who of biopharmas failed the NIH’s inpatient COVID-19 study, NRx Pharmaceuticals has now flunked a related trial in severely ill patients, sending its share price down to the basement.

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Biotech co-founder arrested on murder-for-hire charges

U.S. officials have arrested Enochian BioSciences co-founder Serhat Gümrükcü. The researcher is charged with conspiring to use interstate commerce facilities in the commission of murder-for-hire which resulted in a death.

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Flagship unveils ProFound Therapeutics with $75M to explore trove of new proteins

Flagship Pioneering-run ProFound Therapeutics has unveiled with $75 million to further develop a trove of newly discovered proteins.

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Avadel's shares crumble as narcolepsy drug delayed yet again, this time on patent issue

Approval for Avadel’s narcolepsy drug has been set back to 2023 on a patent issue flagged by the FDA.

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Vertex scoops up Catalyst’s complement pipeline for $60M cash

More the six months after Catalyst Biosciences put a “for sale” sign on its hemophilia program, the company is parting with the rest of its pipeline, selling off its line of preclinical-stage complement therapies to Vertex Pharmaceuticals for $60 million cash.

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New T-cell tech zooms in on immune disease risk. GSK is diving in to search for new drug targets

Researchers have mapped out changes in T-cell activation—a key immune regulation process—moving the dial closer to discovering root causes of immune diseases, with big pharma GlaxoSmithKline already using the science to inform early drug discovery.

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J&J debuts rap video, enlists Bollywood star to recruit young people for India's TB fight

Janssen India is looking to the younger generation to help fight the country's TB epidemic with assistance from a famous Bollywood actress and an Indian hip-hop star.

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CMS extends annual postpartum Medicaid, CHIP coverage to 4 states

CMS has announced another four states have gotten federal approval to extend Medicaid and CHIP postpartum coverage up to 12 months past birth.

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Bristol's Abecma, Amgen's Lumakras headline record-setting oncology launch class as costs continue to balloon: IQVIA

A flurry of innovation in oncology has led to a record number of new cancer drugs launched globally in 2021. But spending on oncology medicines also reached to a new high.

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Siemens Healthineers adds VR training for mobile 3D X-ray system with PrecisionOS collab

Using PrecisionOS’ technology—which is installed on Oculus VR headsets—surgeons and OR technicians will be able to complete practice sessions using Siemens' Cios Spin machine together, giving them the chance to share their expertise with one another and improve their collaboration in the operating room.

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Resources

Executive Summary: PBPK Modelling for Optimizing Controlled Release Dosage Form Development

In this executive summary, we describe the benefits of controlled release, look at how to determine whether a drug is suitable for controlled release, review the application of PBPK modelling in controlled release formulation development and discuss how modified release products can be developed to deliver optimal patient outcomes.

Whitepaper: Gain Operational Speed and Velocity by Sharing Quality Incident Data

Quality operations guide your organization through regulatory compliance processes and safeguard your products, processes, and reputation. But your team is capable of so much more. Quality incident data and processes can be a driver of significant business value if shared with other stakeholders.

Whitepaper: Intranasal Drug Product Development: Formulation to Manufacturing

What are key considerations for intranasal delivery in the treatment of acute and chronic conditions?

Whitepaper: Catalent Pulmonary & Nasal Delivery Capabilities Sheet

Did you know Catalent has newly expanded in-house capabilities spanning clinical and commercial scale manufacturing for DPIs, unit-dose, bi-dose and preserved multi-dose nasal sprays?

eBook: Orally Inhaled & Nasal Drug Delivery: A Pipeline of Opportunities

Orally Inhaled & Nasal Drug Delivery: A Pipeline of Opportunities

Whitepaper: Medical Affairs Metamorphosis: Trends Driving Change & What They Mean

Recent trends are driving big changes in Medical Affairs. This paper explores why, and what MA teams can do to stay ahead of the curve.

eBook: Streamline HCP interactions management

Don’t miss these critical considerations when evaluating your HCP interactions management program.

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