Jazz tries out M&A at BIO

Today's Big News

Jun 6, 2023

Editor's Corner—When ASCO dueled with the world's biggest pop star, Swift Biotech was ready for it


ASCO: J&J's multiple myeloma combo produces déjà vu with 96% Carvykti-like response


BIO: Jazz is auditioning new bandmates in an M&A market ripe with talent


Ultragenyx brittle bone drug barrels into pivotal trial after triggering swift improvements in phase 2


Scientists pinpoint location of plaque ruptures, and a protein that predicts them


Erasca erases part of pipeline after revealing mixed hand of early-phase cancer data


Acepodia picks up strong hand to advance cell therapies in $100M series D


Canadian biotech narrows trial population to lift solid tumor drug out of FDA hold

The Top Line Podcast: don’t miss out on the newest episode where we discuss ASCO data, rising health tech stars, and more. Listen now.

 

Featured

Editor's Corner—When ASCO dueled with the world's biggest pop star, Swift Biotech was ready for it

As usual, ASCO occurred the first weekend in June in Chicago. Except this year, a superstar whose reputation precedes her put on a rivaling show right next door.
12-14
Jun
San Diego, CA
 

Top Stories

ASCO: J&J's multiple myeloma combo produces déjà vu with 96% Carvykti-like response

Johnson & Johnson has seen response rates as high as 97% in multiple myeloma before but this time, it’s not for Carvykti. No, this time the healthcare giant’s pharmaceutical unit Janssen is shining the spotlight on a combo study for talquetamab and Tecvayli.

BIO: Jazz is auditioning new bandmates in an M&A market ripe with talent

“It's a good time to be investing in and acquiring innovation,” Jazz Pharmaceuticals CEO Bruce Cozadd says, as the company scouts for deals at the BIO International Convention.

Ultragenyx brittle bone drug barrels into pivotal trial after triggering swift improvements in phase 2

Ultragenyx Pharmaceutical has strengthened the evidence on its brittle bone disease prospect. The drug candidate triggered fast, significant improvements in bone mineral density, encouraging the biotech to race into the phase 3 portion of the study and try to wrap up enrollment this year.

Scientists pinpoint location of plaque ruptures, and a protein that predicts them

Researchers have uncovered new details about the mechanisms that cause plaques in arteries to rupture, paving the way for new tests to predict what patients are most at risk of a heart attack or stroke.

Erasca erases part of pipeline after revealing mixed hand of early-phase cancer data

Erasca is cutting back its pipeline. The biotech has deprioritized several applications of one of its most advanced candidates after getting a look at lackluster data and put a KRAS inhibitor on the back burner in response to the “increasingly competitive landscape for small- and mid-cap biopharma companies.”

Acepodia picks up strong hand to advance cell therapies in $100M series D

Acepodia is ready to ante up its bet on cell therapy after turning over a brand new $100 million series D financing that will support the biotech's pipeline of medicines for solid tumors and hematological cancers.

Canadian biotech narrows trial population to lift solid tumor drug out of FDA hold

The FDA has signed off on an amended trial protocol for Theratechnologies’ solid tumors medicine, lifting its clinical hold and setting the Canadian biotech free to proceed.

ASCO: Merck's Keytruda trips in EGFR lung cancer as Roche's Tecentriq fails in kidney cancer

Detailed data at ASCO 2023 showed how Merck's Keytruda and Roche's Tecentriq failed to improve outcomes for patients who had tried prior standard treatment in EGFR-mutated non-small cell lung cancer and kidney cancer, respectively.

ASCO: Novocure's tumor-treating electric fields nearly double survival for some lung cancer patients

Study results that Novocure presented at the American Society of Clinical Oncology annual meeting Tuesday scratched a seven-year itch: According to the company, it's the first phase 3 clinical trial in at least as long to detail a therapy’s ability to significantly improve the survival rate for patients with platinum-resistant, metastatic non-small cell lung cancer.

Younger people driving more high-cost claims for employers: survey

Self-insured employers face a fairly new development: More younger people are driving high-cost claims, according to a new survey.

Merck challenges HHS on Medicare drug price negotiations, alleging violations of the Constitution

The pharma industry has voiced loud complaints about the Biden administration's Inflation Reduction Act, specifically focusing on a clause that will allow Medicare to negotiate the prices of top-selling pharmaceuticals. But now the industry is taking its arguments to the courts.
 
Fierce podcasts

Don't miss an episode

'Podnosis': 'Game-changing' generative AI and gender-affirming healthcare

This week on "Podnosis," we discuss why generative AI can be "game-changing" in healthcare. We also take a second look at an episode on gender-affirming healthcare
 

Resources

Whitepaper

Autoantibodies: Powerful Biomarkers in Cancer Precision Medicine

Autoantibody screening is promising for early cancer detection with the potential to improve the whole treatment decision tree, providing a less invasive, powerful approach.
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Designing an Optimal APAC Clinical Supply Chain

Discover key considerations that every trial sponsor should know when navigating the complex clinical supply distribution landscape across Asia-Pacific.
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Running Decentralized Trials at Scale

Explore how clinical supply can be scaled up as decentralized programs progress, and how technological solutions can accelerate trial deployment.
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Questions You Need to Ask Your CRO About Clinical Supply

Planning on using a CRO to support your next clinical study? This infographic outlines critical areas to address at the start of the relationship in order to ensure that budget and timelines keep on track for the duration of the trial.
eBook

Strategies to Optimize Clinical Trial Enrollment Timelines

See how clinical trial sponsors can build stronger strategies to address challenges across the patient enrollment funnel, starting with four necessary steps.
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Commercializing Gene Therapies, Part 4 – Market Entry

This paper outlines various market archetypes and key considerations leaders must address when prioritizing new potential markets for gene therapies.
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ChatGPT in Drug Discovery: Rise of Large Language Models

ChatGPT shows promise in drug discovery for information extraction, scientific text authoring, hypothesis prediction, and chemical entity prediction. This whitepaper explores its potential to streamline research, delving into its technology, applications, and limitations.
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Discovering High-Affinity, Functional Anti-GLP-1R Antibodies

Learn how a GPCR-focused library with a cell-based biopanning strategy led to the discovery of 13 high-affinity and selective anti-GLP-1R antibodies with highly developable therapeutic properties.
Research

How Lilly’s Legal and Library Services Empower Teams Across the Drug Development Pipeline

What role do the Library and Legal teams play in the drug development pipeline at Lilly? An import one – find out how.
 

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