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Today's Rundown

Featured Story

Eli Lilly’s R&D revolving door spins again as Leena Gandhi heads back to Dana-Farber

A little over two years into her stint leading immuno-oncology medical development at Eli Lilly, Leena Gandhi M.D., Ph.D., is hitting the exit.

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Top Stories

After a turbulent few months, Germany takes a stake in COVID-19 vaccine drugmaker CureVac

Germany is taking a 23% stake in privately owned CureVac as it preps to push on with work for its mRNA vaccine against the COVID-19 pandemic.

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CRISPR and Vertex show durability of gene-editing therapy, hoping for one and done treatment 

CRISPR Therapeutics and Vertex have presented updated data on the first patients treated with their CRISPR/Cas9 gene-editing therapy. The partners now have evidence that one-time treatment with CTX001 improves outcomes in sickle cell disease and beta thalassemia patients for up to 15 months.

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Sponsored: The Future of Clinical Research: Digitally Transforming What’s Possible

Sponsors are transforming and future-proofing their clinical research by incorporating virtual options in study protocols. Discover why patients are key to the success of these digital strategies.

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UCB's bimekizumab blows J&J's Stelara away in phase 3, raising expectations for Cosentyx showdown

UCB has presented detailed phase 3 data on psoriasis prospect bimekizumab, raising expectations that it can deliver a telling blow to Novartis’ Cosentyx in an upcoming head-to-head study. Shares in UCB, a company valued above $20 billion, jumped 14% in response to the readout. 

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Takeda-partnered Shattuck nabs mighty $118M funding round for immunotherapy, autoimmune work

After getting off a $46 million series A in 2018, Texas-based biotech Shattuck Labs has followed up with a major $118 million second funding round.

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Sensei Biotherapeutics shakes up R&D suite as it nabs new CMO from Merus

It was just two years ago that immuno-oncology biotech Sensei hired a new chief medical officer; now, it’s at it again, tapping Merus exec Marie-Louise Fjällskog, M.D., Ph.D., as it latest CMO.

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Gene editing turns immune cells into more potent cancer killers

University of California, San Diego researchers edited a gene called CISH from the immune system's natural killer (NK) cells, freeing up the signaling of cytokines—molecules that direct immune cells to destroy invaders. The edited NK cells cleared leukemia in mouse models and could prove promising as an off-the-shelf cell therapy for some cancers, the researchers said.

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ADA: Abbott's real-world data show FreeStyle Libre lowered A1c in Type 2 diabetes, with or without insulin

Real-world data showed the use of a continuous glucose monitoring system was able to substantially reduce A1c levels among people with Type 2 diabetes regardless of whether they were taking insulin.

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ADA: Novo Nordisk's long-lasting insulin candidate matches Lantus in phase 2

Novo Nordisk has long been working on drugs that can help people earlier on in their diabetes and keep them from progressing to insulin treatment. But that doesn’t mean it’s not also working to improve the insulin options out there for those who do need it.

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Enrollment Showcase

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Resources

Case Study: Pharma Sponsor Enlists Cenduit to Rescue a Multi-Country, Multi-Site Oncology Study

Download this case study to read how Cenduit helped one client successfully navigate mid-study changes to medication management.

Whitepaper: 4 Ways to Keep Pace with Big Pharma, Even On a Start-Up Budget

Learn four ways to squeeze more value from your limited R&D resources.

eBook: Advanced Analytical Approaches for Improved Development of Cell and Gene Therapies

Download this eBook and Learn the Advanced Analytical Approaches for Improved Development of Cell and Gene Therapies

Whitepaper: Brand Revitalization with RP Scherer Softgel Solutions for Analgesics

In a series of innovation sessions, Catalent RP Scherer softgel capsules were quickly identified as the ideal solution to drive incremental growth. Learn more.

Whitepaper: 7 Keys to Success in Europe

White paper describing 7 keys to success for any biopharma company that is entering (or thinking about entering) Europe.

Whitepaper: Rapid BYOD Build Timelines

This white paper covers a Phase III case study; BYOD advantages and misconceptions; and regulatory, copyright, and equivalency considerations.

Whitepaper: Keep Your GI Trials Moving During COVID-19

Learn how GI specific data capture solutions can support virtual and hybrid trials during COVID-19.

Whitepaper: The Evolution and Importance of Biomedical Ontologies for Scientific Literature

Dive into the history of biomedical classification and how these systems have evolved to address new technology and use cases.

Whitepaper: Pandemic respiratory vaccine clinical trials: a departure from business as usual

Download this whitepaper to learn more about the success factors that are required to keep a pandemic respiratory vaccine trial running at optimal speed and efficiency.

Case Study: Establishing Parameters for Success

Learn about a real-world example of how clinical supply management expertise was applied to overcome inventory challenges for a complex, global study.

Fact Sheet: Forecasting to Optimize Clinical Trial Supply Management

Whether a study is simple or highly complex, forecasting and simulation reports serve as data driven communication tools to help minimize risks and keep the study on track. Learn more about forecasting solutions for informed decision making and supporting contingency planning for clinical study.

eBook: Expecting the Unexpected: Strategies for Efficient Clinical Supply Management and Forecasting

Learn how to drive excellence within the forecasting process and utilize forecasting throughout the clinical study to better plan clinical supply budgets and project timelines. Explore how to identify potential supply-related issues before they can negatively impact your study.

Case Study: Precision Analytics for Product Launch and Growth

Pharma launch teams spend significant resources on data and analytics with limited ROI. Read this case study to learn how a Life Sciences company identified two times more patients best suited for therapy, using Clarify’s deep and longitudinal patient and HCP insights. 

Virtual Event: Cardiac Safety London Online

Join us for a day of discovery as global experts in Cardiology, Pharmacology and Diabetes discuss state of the art methods in early phase clinical research.

Whitepaper: Why Your Business Needs An Effective Cloud Strategy To Survive Now

Businesses must maintain pre-pandemic levels of productivity with smaller IT budgets. Learn why an effective Cloud Strategy is imperative for success in these unprecedented times.

Events