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Today's Rundown

Featured Story

AbbVie spends $60M, with $805M in biobucks, for Alpine Immune's lupus asset

AbbVie is spending $60 million upfront for a midstage lupus and autoimmune asset currently developed by Alpine Immune.

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Top Stories

Pfizer, Sangamo flesh out hemophilia gene therapy data ahead of phase 3

There’s a pivotal trial in the offing for Pfizer and Sangamo’s hemophilia A gene therapy, but, in the meantime, the duo is unveiling updated phase 1/2 data. The highest dose of the treatment helped patients make functioning blood-clotting factors for a sustained period, underlining its potential to free hemophilia A patients from lifelong treatment.

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BioMarin’s hemophilia gene therapy ‘Roc solid’ after 4 years

Four years on, BioMarin’s hemophilia A gene therapy is still going strong—it staved off bleeding episodes in patients with hemophilia A and reduced their reliance on infusions of a blood-clotting factor that they lack.

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Sponsored: NYC Biotechs Rally to Test for COVID-19

Hit hard by COVID-19, five NYC biotech companies develop innovative diagnostic technologies that provide faster and better tests.

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Dicerna nabs speedy review voucher for leading RNAi drug

RNA biotech Dicerna has nabbed a priority review voucher as part of its new rare pediatric disease designation for leading drug nedosiran.

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Sponsored: The Future of Clinical Research: Digitally Transforming What’s Possible

Sponsors are transforming and future-proofing their clinical research by incorporating virtual options in study protocols. Discover why patients are key to the success of these digital strategies.

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Ubiquigent DUB inhibitor pact survives Bristol-Celgene merger

Bristol Myers Squibb is continuing a drug discovery collaboration with Ubiquigent that it inherited in its merger with Celgene. The Big Pharma recently scrapped an alliance with Jounce Therapeutics that was formed by Celgene but is sticking with deubiquitinase (DUB) enzyme specialist Ubiquigent.

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Treating age-related diseases with a CAR-T that targets 'senescent' cells

Many age-related diseases like liver fibrosis and diabetes have been partly attributed to cellular "senescence," a zombie-like state in which cells stop proliferating. A team at Memorial Sloan Kettering Cancer Center is targeting these diseases with CAR-T cells that are designed to clear senescent cells.

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Digital pill developer Proteus files for bankruptcy

Proteus Digital Health—makers of an ingestible sensor embedded within a pill to track medication usage—has filed for bankruptcy, after failing to raise funding in part due to the COVID-19 pandemic.

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Enrollment Showcase

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Resources

Case Study: Pharma Sponsor Enlists Cenduit to Rescue a Multi-Country, Multi-Site Oncology Study

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Whitepaper: 4 Ways to Keep Pace with Big Pharma, Even On a Start-Up Budget

Learn four ways to squeeze more value from your limited R&D resources.

eBook: Advanced Analytical Approaches for Improved Development of Cell and Gene Therapies

Download this eBook and Learn the Advanced Analytical Approaches for Improved Development of Cell and Gene Therapies

Whitepaper: Brand Revitalization with RP Scherer Softgel Solutions for Analgesics

In a series of innovation sessions, Catalent RP Scherer softgel capsules were quickly identified as the ideal solution to drive incremental growth. Learn more.

Whitepaper: 7 Keys to Success in Europe

White paper describing 7 keys to success for any biopharma company that is entering (or thinking about entering) Europe.

Whitepaper: Rapid BYOD Build Timelines

This white paper covers a Phase III case study; BYOD advantages and misconceptions; and regulatory, copyright, and equivalency considerations.

Whitepaper: Keep Your GI Trials Moving During COVID-19

Learn how GI specific data capture solutions can support virtual and hybrid trials during COVID-19.

Whitepaper: The Evolution and Importance of Biomedical Ontologies for Scientific Literature

Dive into the history of biomedical classification and how these systems have evolved to address new technology and use cases.

Whitepaper: Pandemic respiratory vaccine clinical trials: a departure from business as usual

Download this whitepaper to learn more about the success factors that are required to keep a pandemic respiratory vaccine trial running at optimal speed and efficiency.

Case Study: Establishing Parameters for Success

Learn about a real-world example of how clinical supply management expertise was applied to overcome inventory challenges for a complex, global study.

Fact Sheet: Forecasting to Optimize Clinical Trial Supply Management

Whether a study is simple or highly complex, forecasting and simulation reports serve as data driven communication tools to help minimize risks and keep the study on track. Learn more about forecasting solutions for informed decision making and supporting contingency planning for clinical study.

eBook: Expecting the Unexpected: Strategies for Efficient Clinical Supply Management and Forecasting

Learn how to drive excellence within the forecasting process and utilize forecasting throughout the clinical study to better plan clinical supply budgets and project timelines. Explore how to identify potential supply-related issues before they can negatively impact your study.

Case Study: Precision Analytics for Product Launch and Growth

Pharma launch teams spend significant resources on data and analytics with limited ROI. Read this case study to learn how a Life Sciences company identified two times more patients best suited for therapy, using Clarify’s deep and longitudinal patient and HCP insights. 

Virtual Event: Cardiac Safety London Online

Join us for a day of discovery as global experts in Cardiology, Pharmacology and Diabetes discuss state of the art methods in early phase clinical research.

Whitepaper: Why Your Business Needs An Effective Cloud Strategy To Survive Now

Businesses must maintain pre-pandemic levels of productivity with smaller IT budgets. Learn why an effective Cloud Strategy is imperative for success in these unprecedented times.

Events