CRISPR Tx drops on pipeline update
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Today's Rundown

Featured Story

Galapagos finally takes M&A plunge, spending $251M for 2 biotechs in CAR-T push

Galapagos CEO Paul Stoffels, M.D., has finally taken the plunge on M&A. The newly minted chief executive has signed not one but two deals in an attempt to right the ship, bringing two small biotechs aboard for a combined 239 million euros ($251.4 million).

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Top Stories

Novartis plots Precision attack on sickle cell, paying $75M and putting up $1.4B in biobucks to form in vivo gene editing pact

One year after Intellia’s landmark data, Novartis is making a play for the in vivo gene editing market. The move sees the Swiss pharma pay Precision BioSciences $75 million upfront, with up to $1.4 billion in milestones, to secure rights to a potential treatment for sickle cell disease and beta thalassemia.

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CRISPR Tx's Innovation Day dragged down by multiple myeloma replacement, lackluster results in kidney cancer

Gene editing giant CRISPR Therapeutics is moving away from multiple myeloma candidate CTX120, while a small, separate dataset released yesterday sent the company’s stock plummeting.

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Axcella's CEO knows people are tired of the pandemic. But long COVID patients need help, too

Visiting Washington, D.C., last week, Axcella CEO Bill Hinshaw is trying to enlist congressional allies to help with long COVID. He’s the first to admit that it’s not an easy sell.

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Beacon of Hope: Novartis commits $17.7M to set up clinical trial centers in historically Black medical schools

Novartis has invested another $17.7 million as part of a 10-year plan to address racial inequalities in clinical trials. The Swiss pharma and its U.S. foundation set up the Beacon of Hope initiative in July 2021 in collaboration with 26 historically Black colleges, universities and medical schools.

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Appetite for allergies: Alladapt banks $119M to push immunotherapy through trials

Alladapt Immunotherapeutics has refilled the bank balance with $119 million in institutional financing from the likes of Novartis, which will be used to follow the biotech's dream of developing the first FDA-approved therapy to treat the majority of food allergy patients.

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Patient empowerment goes from 'trend to permanent movement' as cancer trial interest grows

Cancer patients from diverse backgrounds are finding empowerment in taking charge of their care as interest in clinical trial participation grows, according to TrialJectory.

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Game on, Pfizer: Merck's Vaxneuvance boosts pneumococcal vaccine fight with coveted pediatric nod

The FDA has blessed Merck's pneumococcal vaccine Vaxneuvance for children ages 6 weeks to 17 years, giving the company a running start on its next generation pneumococcal vaccine race with Pfizer.

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ViiV, Gilead and Janssen notch top scores with HIV/AIDS patient groups; pricing, access still pain points

Patient groups may view pharma more favorably thanks to its work during the pandemic, but HIV and AIDS patients groups are a tougher sell, according to a new survey.

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AHIP 2022: Addressing drug prices requires all stakeholders at the table, experts say

LAS VEGAS—Stemming the tide of rising drug prices will require bringing all the major players to the table, experts said Tuesday.

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Resources

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Whitepaper: Catalent Pulmonary & Nasal Delivery Capabilities Sheet

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eBook: Orally Inhaled & Nasal Drug Delivery: A Pipeline of Opportunities

Orally Inhaled & Nasal Drug Delivery: A Pipeline of Opportunities

Whitepaper: Intranasal Drug Product Development: Formulation to Manufacturing

What are key considerations for intranasal delivery in the treatment of acute and chronic conditions?

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