Abbott, ADA partner to boost T2 glucose monitor use

Today's Big News

Jun 26, 2023

Pfizer drops oral obesity drug after seeing liver safety concern, focuses on less-convenient candidate


Lilly links oral obesity drug to 15% weight loss, setting bar for Pfizer in blockbuster battle


Biogen shareholders vote in Susan Langer as director despite relationship with former board member


ADA: Abbott pushes for widespread CGM use in Type 2 diabetes with WeightWatchers, ADA collabs


Another clinical failure in lung disorder sends FibroGen hunting for cost savings—as shares crash

 

Featured

Pfizer drops oral obesity drug after seeing liver safety concern, focuses on less-convenient candidate

Pfizer is dropping one of its oral obesity drug candidates after seeing elevated liver enzymes in clinical trials. The setback leaves the Big Pharma’s near-term prospects resting on a candidate that is given twice as often as rival weight loss medicines in development at Eli Lilly and Novo Nordisk.
18-19
Jul
July 18-19, 2023 | Jersey City, NJ
 

Top Stories

Lilly links oral obesity drug to 15% weight loss, setting bar for Pfizer in blockbuster battle

Eli Lilly has laid down a marker in the race for the oral obesity market, linking its GLP-1 receptor agonist orforglipron to 14.7% weight loss at 36 weeks. The result sets a high efficacy bar for Pfizer but leaves ample room to improve on tolerability.

Biogen shareholders vote in Susan Langer as director despite relationship with former board member

Despite the controversy surrounding a relationship with departing director Alex Denner, Susan Langer has secured enough investor support to join Biogen’s board.

ADA: Abbott pushes for widespread CGM use in Type 2 diabetes with WeightWatchers, ADA collabs

Abbott unveiled a new partnership with the American Diabetes Association and kicked off its previously announced WeightWatchers collaboration during the ADA’s annual scientific sessions in San Diego on Saturday.

Another clinical failure in lung disorder sends FibroGen hunting for cost savings—as shares crash

Once heralded as a potential blockbuster, FibroGen’s pamrevlumab did not live up to expectations in a phase 3 study for a chronic lung disease. It’s the second time this month that the therapy missed the mark in a clinical trial, putting the San Francisco biotech into survival mode.

Erytech's merger with Pherecydes reaches the finish line after contentious few months

Erytech's merger with Pherecydes has reached the finish line after a contentious battle with an activist investor. The proposed merger was greenlighted by Erytech's shareholders, denying Akkadian Partners' request to reject it.

How Eversana roared back from rejection to craft Cannes-winning campaign hospitals couldn't ignore

Next time a project hits a setback, think of Eversana Intouch’s Cannes gold lion winning campaign. The New York agency pivoted around a stumbling block that threatened to sink its campaign—and turned the hitch into a strength that bolstered its core message about the inequality of breast cancer care.

ADA: Medtronic's MiniMed 780G insulin pump, simplified meal reporting help kids and teens better manage diabetes

A range of study data presented by Medtronic at the American Diabetes Association’s annual scientific sessions over the weekend touts the benefits of its newly FDA-approved MiniMed 780G insulin pump technology for kids and teenagers.

ADA: Novo Nordisk, Eli Lilly show progress for oral GLP-1 treatments for obesity

The potential advantages of a daily-pill version of popular GLP-1 drugs for Type 2 diabetes and obesity are obvious compared to the weekly-injection routine most patients taking these drugs undergo. Last weekend at the American Diabetes Association Scientific Sessions in San Diego, market leaders Novo Nordisk and Eli Lilly presented data that showed their investigative oral GLP-1 treatments are making progress.

Blackstone injects $140M cash into Sutro Biopharma for Vaxcyte royalties

Investor Blackstone Life Sciences is paying Sutro Biopharma $140 million cash and throwing in another potential $250 million in biobucks in exchange for royalties on possible future sales of Vaxcyte’s products.

Lundbeck replaces retiring CEO Dunsire with UCB exec after breaking sales record

Lundbeck CEO Deborah Dunsire is retiring on a high note in the neuroscience company’s history. After hitting the company's highest quarterly revenue in the first quarter, the five-year Lundbeck chief executive will pass the baton to UCB's neurology head.

ADA: Gelesis study data position stomach-filling capsule as alternative to GLP-1s for weight loss

Gelesis’ oral hydrogel technology was cleared by the FDA in 2019 based on clinical trials showing that it could help around 60% of users reduce their body weight by at least 5% over the course of six months—and a new study shows that the tech has largely maintained those results throughout its launch into real-world settings.

After early win in type 1 diabetes, Vertex joins forces with Lonza on new cell therapy production plant where it plans to employ 300

To support production of VX-880 and a second clinical candidate for type 1 diabetes, VX-264, Vertex and Lonza are teaming up on process development and scale-up for the manufacturing of the drugmaker’s portfolio of stem cell-derived, fully differentiated insulin-producing islet cell therapies.

Conformis stock soars on buyout deal from fellow implant maker restor3d

Conformis, a nearly two-decade-old maker of 3D-printed, personalized orthopedic implants, has agreed to be acquired by a competitor in the space: restor3d, a North Carolina startup that spun out of Duke University in 2017.
 
Fierce podcasts

Don't miss an episode

'The Top Line': The most expensive drugs in the US, plus this week's headlines

This week on "The Top Line," we discuss the most expensive drugs in the U.S., plus Eli Lilly's recent acquisition, the latest company to challenge the Inflation Reduction Act, and the rest of the week's headlines.
 

Resources

Whitepaper

Enhance the cost-effectiveness of your GMP chemical supply chain

Learn how to develop a high-performing supply chain for cGMP chemicals used throughout your bioprocessing workflows.
Whitepaper

Autoantibodies: Powerful Biomarkers in Cancer Precision Medicine

Autoantibody screening is promising for early cancer detection with the potential to improve the whole treatment decision tree, providing a less invasive, powerful approach.
Whitepaper

Running Decentralized Trials at Scale

Explore how clinical supply can be scaled up as decentralized programs progress, and how technological solutions can accelerate trial deployment.
Whitepaper

Designing an Optimal APAC Clinical Supply Chain

Discover key considerations that every trial sponsor should know when navigating the complex clinical supply distribution landscape across Asia-Pacific.
Whitepaper

Clinical Supply Solutions for the Asia-Pacific Region

Learn how Catalent’s extensive network across APAC can meet a wide range of clinical supply needs for sponsors conducting trials within the region.
eBook

Strategies to Optimize Clinical Trial Enrollment Timelines

See how clinical trial sponsors can build stronger strategies to address challenges across the patient enrollment funnel, starting with four necessary steps.
Whitepaper

Commercializing Gene Therapies, Part 4 – Market Entry

This paper outlines various market archetypes and key considerations leaders must address when prioritizing new potential markets for gene therapies.
 

Industry Events

 

Upcoming Fierce Events

18-19
Jul
July 18-19, 2023 | Jersey City, NJ
11-14
Sep
Philadelphia, PA
13
Sep
Philadelphia, PA
19-21
Sep
Virtual Event
26-28
Sep
Philadelphia, PA

View all events