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June 29, 2017

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Today's Rundown

  1. Sarepta hires ex-Allergan leader with M&A history as CEO

  2. Coherus slashes staff by a third after Amgen biosimilar knockback

  3. Merck KGaA steps up Hippo pathway cancer pact with CRT

  4. [Sponsored] Getting cancer vaccines right: Key challenges and solutions for neoantigen identification

  5. Atlas rolls out its XI biotech fund, with $350M up for grabs

  6. Evotec in neurology iPSC drug discovery collaboration with stem-cell specialist Censo

  7. INC boosts presence in Japan, Asia with new move

  8. Johnson & Johnson’s DePuy bolsters spine business with Sentio buy

  9. As Congress battles over healthcare, Johnson & Johnson CEO says real reform will take time—and cooperation

Featured Story

Sarepta hires ex-Allergan leader with M&A history as CEO

Doug Ingram has become the latest person to take a turn as Sarepta Therapeutics CEO. The former Allergan president is set to replace Ed Kaye, M.D., putting him in charge of turning Sarepta into a successful commercial-stage biotech with a pipeline of promising programs.

Top Stories

Coherus slashes staff by a third after Amgen biosimilar knockback

The FDA's rejection of Coherus BioSciences' biosimilar version of Amgen's Neulasta means that 51 people at the company will lose their jobs, reducing its headcount by around 30%.

Merck KGaA steps up Hippo pathway cancer pact with CRT

Merck KGaA has taken its oncology collaboration with Cancer Research Technology (CRT) to the next level. The move sees Merck and CRT kick off a full drug discovery program aimed at the Hippo pathway after spending a year on target validation.

[Sponsored] Getting cancer vaccines right: Key challenges and solutions for neoantigen identification

Neoantigen-based cancer vaccines represent new, truly personalized therapeutic approaches to treating cancer.

Atlas rolls out its XI biotech fund, with $350M up for grabs

Cambridge venture capital firm Atlas Venture has raised its 11th fund, totaling $350 million, as it looks to advance its mission of “doing well by doing good” for biotechs.

Evotec in neurology iPSC drug discovery collaboration with stem-cell specialist Censo

Evotec has reached a collaboration with Censo Biotechnologies, using the latter’s patient-derived induced pluripotent stem cells to expand its platform for drug discovery.

INC boosts presence in Japan, Asia with new move

After recently merging with fellow CRO InVentiv in a new company worth around $7.4 billion, INC says it is now focused on growing its Asia presence with moves and an expansion.

Johnson & Johnson’s DePuy bolsters spine business with Sentio buy

Johnson & Johnson’s DePuy Synthes has acquired Sentio, which makes nerve localization technology for spine surgery, for an undisclosed amount.

As Congress battles over healthcare, Johnson & Johnson CEO says real reform will take time—and cooperation

While Republican senators work feverishly on a healthcare bill, one prominent pharma CEO says overhauling the system won't take a few weeks of work. Think years, even decades—and he'd like Democrats to be at the table, too.

News of Note

The FDA comes good on its orphan label backlog just one week after new Commissioner Scott Gottlieb's promise to the Senate. FDA statement

Omeros is biting back at a highly critical report, accusing “Art Doyle” of shorting the stock and calling the report "replete with falsehoods, misleading statements and incorrect analyses and conclusions." Release

Chi-Med and partner AstraZeneca have started their global late-stage test of savolitinib in papillary renal cell carcinoma. Statement

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[Webinar] Within-Subject Clinical Trials: Intro to New Methods & Stat. Models

In this webinar, we will introduce the rapidly-evolving within-subject clinical trial (WSCT) methods for early phase evidence generation that require fewer people, less time, and usually less funding than traditional early phase methods.

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