The 15 highest-paid CEOs in biopharma
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WELCOME TO FIERCE LIFE SCIENCES WEEKLY DIGEST

Last year was a curious one in the world of biopharma CEO compensation, as several high-profile chiefs made for the exit—some as part of routine transitions, while other departures have presaged larger problems, including at home and at the company. And as has been the case for many years, 2021's top-paid execs were exclusively men, but female biopharma leaders have been gaining on the pack in recent months. The full list, plus our top stories of the week, follow below. 

Featured Story

'Leaner and simpler': Novartis details plans to cut 8,000 jobs worldwide

For months, Novartis has hinted at layoffs coming for some of its global staff. Now, the news has come down from HQ.

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Top Stories Of The Week

Galapagos says out with the old, in with the new, as respiratory drug sent back to Molecure

While Galapagos is stocking its pipeline by way of two acquisitions, the biotech is also cleaning house, sending the rights for a respiratory disease drug back to Molecure.

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The 15 highest paid biopharma CEOs of 2021

In a year in which biopharma revenues increased dramatically, especially among companies that brought COVID-19 products to the market, many firms laid out eye-popping pay packages for their chief executives. Bookending this year's list are longtime CEOs who retired from powerhouse U.S. companies during the year—No. 1 Alex Gorsky of Johnson & Johnson and No. 15 Ken Frazier of Merck.

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'Science doesn't care' about markets: Arch raises nearly $3B amid tough times for biotechs

Arch Venture Partners has raised nearly $3 billion in a new venture fund, a glimmer of hope as biotechs large and small lick their wounds amid a market downturn that's lasted more than a year. The early investment firm was able to secure roughly a billion more dollars this time around compared to its previous fund.

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BioMarin's hemophilia gene therapy Roctavian wins conditional EU backing amid FDA delay

The future of BioMarin’s first-of-its-kind hemophilia gene therapy remains uncertain at the FDA, but its EU regulatory path now looks clearer. Despite questions about the one-time drug's long-term efficacy, the EMA has recommended a conditional nod.

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M&A is down, but Big Pharma likely to line up 'multiple shots on goal' in 2nd half, PwC says

Deal values are down by 58% and volume has decreased by 33%, but fear not, the pharmaceutical and life sciences industry is poised for a “flurry of deals” in the second half, according to PwC.

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AstraZeneca launches first Evusheld DTC, but without full approval it comes with a different feel

AstraZeneca launched the first ever COVID drug DTC for its prevention antibody, Evusheld, and it’s one of the most unusual and unique commercials you will see this year.

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Cue Health to lay off 170 workers due to 'economic challenges,' COVID test funding cuts

After rocketing to medtech stardom amid the COVID-19 pandemic, Cue Health seems to be drifting back down to Earth.

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Sanofi racks up 2 approvals in Europe for enzyme replacement therapies for rare diseases

On Tuesday morning, Sanofi revealed two approvals from the European Commission—both for enzyme replacement treatments for rare diseases—that speak to CEO Paul Hudson’s mission to "play to win."

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Manipulating T-cell fate to improve CAR-T therapy in solid tumors

Inhibiting a protein could boost the efficacy of CAR-T cells by letting newly activated T cells preferentially differentiate toward long-lasting memory T cells rather than the short-living effector cells, scientists at St. Jude Children’s Research Hospital have shown.

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AstraZeneca chips in another $68.7M to beef up Alexion's manufacturing capabilities in Ireland

AstraZeneca is pouring 65 million euros ($68.7 million) into two manufacturing sites in Ireland, which will increase drug substance production capabilities for AZ's rare disease unit Alexion. The funding comes nine months after AZ revealed a $360 million investment to build a next generation manufacturing site in Dublin.

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'The Top Line' podcast: FDA's coming COVID shot makeover, what's driving new M&A activity, plus this week's headlines

This week on "The Top Line," we discuss what FDA advisors want added to future COVID vaccine doses—and why. Also, experts predict an uptick in dealmaking, particularly for a few key companies.

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Resources

Case Study: Roche cuts feasibility process by 36%

Explore how Cognizant SIP helped Roche streamline its global feasibility process.

eBook: 12 Pitfalls in Europe

For an emerging biopharma company, Europe can be very attractive. But it can also be complex and confusing. This e-book covers the 12 most common pitfalls for companies entering European markets for the first time, offering guidance to help growing companies avoid them and succeed.

Whitepaper: The Most Suitable Dosage Form Technologies for the Oral Delivery of Lipid-Based Formulations

What is the most suitable dosage form technology for the Oral Delivery of Lipid-Based Formulations?

eBook: Download the Cell Therapy Handbook

Explore the new cell therapy handbook from Thermo Fisher Scientific.

Article: Formulation Strategies When Transitioning From Vial to PFS

Learn how formulation development for a PFS affects manufacturing to drive the industry toward optimizing delivery of injectable products and, ultimately, improving patient care.

Whitepaper: Jump Start for Biotech: New Lab Startup Guide

Sponsored by Thermo Fisher Scientific The journey for starting or expanding a lab can be exhilarating, while also being challenging--learn how this free program provides savings and solutions to support your goals.

Whitepaper: Catalent Pulmonary & Nasal Delivery Capabilities Sheet

Did you know Catalent has newly expanded in-house capabilities spanning clinical and commercial scale manufacturing for DPIs, unit-dose, bi-dose and preserved multi-dose nasal sprays?

Whitepaper: Intranasal Drug Product Development: Formulation to Manufacturing

What are key considerations for intranasal delivery in the treatment of acute and chronic conditions?

eBook: Orally Inhaled & Nasal Drug Delivery: A Pipeline of Opportunities

Orally Inhaled & Nasal Drug Delivery: A Pipeline of Opportunities

Events