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July 06, 2016

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Today's Rundown

  1. Vertex, Moderna pair to create mRNA cystic fibrosis treatment

  2. SF startup Carmot nabs discovery deal with Genentech

  3. Medivation plans a bidding war as it rejects Sanofi’s sweetened bid

  4. Biotech trumps IT in venture-backed IPO, M&A

  5. Pfizer, German Merck start first-ever PhIII PD-L1 combo trial for ovarian cancer

  6. Dodgy data analysis sees XBiotech shares plummet

  7. EuroBiotech: After Nasdaq setback, Novartis-backed gene therapy play plans €40M Paris IPO

  8. The Fierce 15 turns 15: A call for biotech startup nominations

Featured Story

Vertex, Moderna pair to create mRNA cystic fibrosis treatment

Vertex Pharmaceuticals and Moderna Therapeutics have partnered in a deal potentially worth more than $300 million to discover and develop messenger ribonucleic acid (mRNA) therapeutics for cystic fibrosis. This is the second major partnership for Moderna in the last week.


Top Stories

SF startup Carmot nabs discovery deal with Genentech

Wednesday, July 6, 2016

Carmot Therapeutics has secured its second major partnership. The latest is a discovery and licensing deal with Roche’s Genentech.

Medivation plans a bidding war as it rejects Sanofi’s sweetened bid

Wednesday, July 6, 2016

Taking a look back at its Genzyme acquisition handbook, Sanofi has turned to CVRs as its new ploy to buy out its highly desired biotech target Medivation--but it will have to get in line as the company opens itself up to other suitors.

Biotech trumps IT in venture-backed IPO, M&A

Tuesday, July 5, 2016

Only 12 IPOs made it out last quarter from U.S. venture-backed companies. Of those, 9 were for biotech companies. That’s just one of the measures showing that biotech has held up relatively well despite a volatile stock market, at least as compared to its information technology peers.

Pfizer, German Merck start first-ever PhIII PD-L1 combo trial for ovarian cancer

Wednesday, July 6, 2016

Pfizer and research partner Merck KGaA have begun late-stage testing of their experimental checkpoint inhibitor avelumab with chemo in certain ovarian cancer patients.

Dodgy data analysis sees XBiotech shares plummet

Wednesday, July 6, 2016

XBiotech tried to talk up a questionable colon cancer trial as being positive, but investors were having none of it as its shares tanked by nearly 50% yesterday.

After Nasdaq setback, Novartis-backed gene therapy play plans €40M Paris IPO

Wednesday, July 6, 2016

GenSight Biologics is looking to bounce back from its failure to list on Nasdaq by pulling off an IPO in its home city of Paris. The Novartis-backed gene therapy player has downsized its ambitions in moving back across the Atlantic, with the currently-targeted IPO haul of €40 million coming in well below the $100 million it first set out to raise on Nasdaq.

The Fierce 15 turns 15: A call for biotech startup nominations

Tuesday, July 5, 2016

It’s an awkward age, to be 15. But that’s exactly where we are with the Fierce 15 this year.

News of Note

Sanofi Genzyme has started a pivotal Phase II/III trial of olipudase alfa for patients with sphingomyelinase deficiency. Release 

The FDA has granted Merrimack a fast-track designation for its seribantumab in non-small cell lung cancer. Statement 

A new NIH-funded center has been set up to study inefficiencies in clinical trials. Release

Resources

[Webinar] Cast Your Vote For An Exclusive Data Services Webinar by SDC

Sponsored by: SDC

Interested in intended use validation of SaaS-based EDC systems? Prefer to discuss rescue study strategies and considerations? How about understanding statistical power for non-statisticians? Vote for your favorite webinar topic to be presented by SDC at DIA on June 28, 2016, 12pm EDT. Cast Your Vote Here to receive your exclusive event invitation and a recording of the webinar after the event.

[Whitepaper] The Remarkable Rebirth of Cancer Immunotherapy

Sponsored by: Covance

Al Blunt, MD, Executive Medical Director, Oncology at Covance discusses how the lessons learned from the past decade of developing targeted therapies are relevant to the future development of cancer immunotherapy. Download today!

[Whitepaper] Complimentary IDMP Report from Gartner

Sponsored by: Veeva Systems

Gartner research on short- and long-term strategies for IDMP compliance.

Events

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