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July 06, 2018

Today's Rundown

Featured Story

Biogen and Eisai’s previously bleak Alzheimer’s study comes back with positive results

A phase 2 Alzheimer’s trial—once nearly consigned to the heap of disappointing attempts against the disease—has re-emerged with new positive results, showing that an anti-amyloid beta protofibril antibody can slow clinical symptom decline, as well as reduce the accumulation of plaque in the brain.

Top Stories

Ionis-backed Dynacure bags €47M to start clinical trials

Dynacure has raised €47 million ($55 million) to take an antisense oligonucleotide therapy into the clinic. The French biotech picked up the centronuclear myopathy prospect from its cofounder, Ionis Pharmaceuticals.

After breathing new life into old mice, senescence startup Cleara bags cash to move toward the clinic

Cleara Biotech has raised seed funding to advance a program that reversed aspects of aging in mice. The modified FOXO4-p53 interfering peptide program made headlines last year when it restored the physical fitness, hair growth and kidney function of mice.

Orion takes repurposed heart failure drug into phase 3 for ALS

Finnish drugmaker Orion Pharma is pressing ahead with a pivotal trial for its amyotrophic lateral sclerosis drug ODM-109, despite mixed results in a phase 2 trial.

Robert Zeldin to take post at Acceleron as its CMO retires

Ablynx’s chief medical officer, Robert Zeldin, has made the jump to Acceleron Pharma to serve as its new CMO, as the company looks to advance development of its lead hematologic drug candidate, luspatercept.

Arming antibiotics with a vaccination-like immune response

Harnessing the power of the body’s immune system has already proven to be effective in treating cancer. Scientists at Lehigh University are now borrowing that idea to power up existing antibiotics’ ability to attack drug-resistant bacteria.

EuroBiotech Report—AbbVie-Galapagos, Novartis-Aveo, Nextbiotix, PredictImmune and Cellect

In this week's EuroBiotech Report, AbbVie dumps its Galapagos combination, Novartis tears up its Aveo pact, Nextbiotix raises €7 million and more. 

FiercePharmaAsia—Sanofi’s Chengdu R&D hub, Takeda’s Osaka HQ sale, I-Mab’s $220M financing

Sanofi launches a global R&D hub in Chengdu, China, with a focus on clinical trial data; Takeda is looking to sell its legacy Osaka headquarters to help fund the Shire buyout; China's antibody player I-Mab nabs a massive $220 million funding round and more.

Chutes & Ladders—Ex-Millennium chief Deborah Dunsire named CEO of Lundbeck

Ex-Millennium chief Deborah Dunsire is named CEO of Lundbeck; Ablynx's CMO will take a post at Acceleron; PredictImmune appoints a new CEO and Novocure promotes its chief commercial officer. Those moves plus more hirings, firings and retirings throughout the industry.

Enrollment Showcase

SBMI Now Offering an Online Graduate Program in Bioinformatics

UTHealth SBMI now offers a M.S. track in clinical and translational bioinformatics.

Resources

[Survey] 2018 eClinical Technology Solutions Survey

Take this anonymous 10-minute survey to share your thoughts on leading eClinical technology solutions and earn up to $55 honoraria. Take the survey now!

[Whitepaper] Is the pharma business model ready for precision medicine?

Blue Latitude Health explores the commercial barriers and new stakeholder connections for pharma companies developing precision medicines, and reveals how to grasp novel opportunities in the new era of healthcare.

[Whitepaper] Getting to First-in-Human Clinical Trials: A Make-or-Break Milestone for Small Biopharmas

“Faster and better” has become the mantra for biopharmaceutical companies as they face intense pressure to get therapies to market faster. Quickly proving efficacy in first-in-human (FIH) trials is a make-or-break milestone for these cash-strapped companies whose hopes hinge upon one or two molecules. Read how CDMOs are responding to this pressure.

[Whitepaper] Compliance Certificate and Training for Life Sciences Professionals

4-day interactive educational program trusted by multi-national companies as part of their compliance training for employees. Explore legal, regulatory and ethical issues faced by pharmaceutical, biotech and medical device manufacturers operating globally. Visit event homepage for session topics.

[Whitepaper] Digitizing the Global Life Sciences Supply Chain: The Critical Role of Digital Transaction Management

Life science companies are experiencing a significant transformation in how they bring new products to market.

Events

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