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Today's Rundown

Featured Story

Sanofi pays $150M upfront, $2B in biobucks to tap protein degrader biotech Kymera

While Sanofi is looking to move more of its R&D in-house, there is still room for deals, and today it’s penned a big one with Fierce 15 winner Kymera Therapeutics.

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Top Stories

Forbion moves into late-stage investing with $210M fund

Forbion has expanded into late-stage biotech investing by holding the first close of a planned €250 million ($284 million) fund. The growth fund, which received money from Eil Lilly, will work with a who’s who of European biotech leaders to execute its investment strategy.

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Can Biogen rebound in ALS? Maybe so, new antisense drug data suggest

It’s no secret: Amyotrophic lateral sclerosis is a tough nut to crack. And no one knows that better than Biogen, which in 2013 saw its last ALS effort go up in flames in phase 3. Now, it’s unveiling full phase 1/2 data for a prospect that emerged from this shift: tofersen, an antisense oligonucleotide licensed from Ionis.

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Sponsored: Keep post-pandemic trials on track: how the right clinical supply chain partner helps sponsors avoid trial disruption, now and going forward

Facing a new reality, pharma and biotech companies must address ongoing clinical trial distribution challenges. Here's how a supply chain partner can help keep your post-pandemic clinical program on track.

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Bayer's heart failure pill hinders kidney disease, heart disease in phase 3

Five years after kicking off a massive phase 3 program, Bayer has good news for its heart failure pill finerenone. The drug beat placebo at staving off progression of kidney disease and lowered the risk of heart attacks and strokes in patients with chronic kidney disease and Type 2 diabetes.

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Tranquis debuts with $30M for immune cell approach to neurodegenerative diseases

Nerve cell inflammation has long been linked to neurodegenerative disease, but as a byproduct rather than a cause. Over the years, scientists have debunked that theory, and, now, Tranquis Therapeutics is launching with $30 million to create a new class of medicines for illnesses like amyotrophic lateral sclerosis and Alzheimer’s disease.

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FDA clears Nonin's hand-held carbon monoxide poisoning meter for first responders

The pulse oximeter manufacturer Nonin Medical received a new FDA clearance for a hand-held vital sign monitor designed to help emergency first responders and firefighters immediately assess patients suffering from a heart attack or physical injury, as well as those affected by carbon monoxide poisoning and smoke inhalation.

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Preventing breast cancer metastasis by reactivating natural killer immune cells

Scientists at Johns Hopkins University discovered that breast cancer cells can alter the function of natural killer cells to promote metastasis. Pairing FDA-approved DNMT inhibitors with receptor-blocking antibodies could prevent this reprogramming and stop breast cancer from spreading, they showed.

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Takeda teams up with Twist Bioscience to boost biologics R&D

Japanese Big Pharma Takeda has paired with synthetic DNA services company Twist Bioscience to level up its biologics capacity.

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Resources

On-Demand Webinar: Fuel gene therapy development and production with modern AAV workflows

On-demand video: fuel gene therapy development and production with modern AAV workflows.

Whitepaper: How to Select the Right Data Partner to Benefit Your Business | Buyer's Guide

With today’s rapidly evolving environment, we have created this five-part content series to highlight pressing issues and topics that are more pertinent today than ever before.

eBook: Cambrex eBook - Small molecules: 2020 vision

The industry trend of outsourcing to CDMOs continues. With more services, capabilities, facilities, and employees than ever before, our experts have contributed more articles to our biggest eBook yet.

White Paper: Patient Switching Behaviors Impact on Adherence and Engagement: A Predictive Analytics and Machine Learning Approach to Improving Hub Performance and Patient Outcomes

How predictive analytics and machine learning have the potential to transform healthcare by predicting “Patient Switching Behaviors.”

Whitepaper: You've Decided on a Multiparticulate Dosage Form. Now What?

Wurster processing is a versatile technique for developing and manufacturing multiparticulates for modified release dosage forms. Read this whitepaper to determine whether Wurster processing is the right option for your project.

Whitepaper: Learn How to Navigate Pediatric Clinical Trials Under the New RACE Act

Collaboration across the industry will be key to meeting the demands of the RACE Act and ensuring pediatric patients receive the care and treatments they need.

Webinar: Blockchain Innovations that Connect & Protect Merck's Supply Chain

Get an inside look… Merck shares its next-generation approach to supply chain protection with new digital platforms, including Blockchain.

eBook: SUPERCHARGE INNOVATION: UNLEASH THE FULL FORCE OF LIFE SCIENCES

Built on advances in Artificial Intelligence (AI), data mining, and information integration into various systems at 100% accuracy, the new era of intelligent automation is integral to life sciences for devising new treatments faster and at a lower expense.

Whitepaper: 4 Ways to Keep Pace with Big Pharma, Even On a Start-Up Budget

Learn four ways to squeeze more value from your limited R&D resources.

eBook: Advanced Analytical Approaches for Improved Development of Cell and Gene Therapies

Download this eBook and Learn the Advanced Analytical Approaches for Improved Development of Cell and Gene Therapies

Case Study: Establishing Parameters for Success

Learn about a real-world example of how clinical supply management expertise was applied to overcome inventory challenges for a complex, global study.

Fact Sheet: Forecasting to Optimize Clinical Trial Supply Management

Whether a study is simple or highly complex, forecasting and simulation reports serve as data driven communication tools to help minimize risks and keep the study on track. Learn more about forecasting solutions for informed decision making and supporting contingency planning for clinical study.

eBook: Expecting the Unexpected: Strategies for Efficient Clinical Supply Management and Forecasting

Learn how to drive excellence within the forecasting process and utilize forecasting throughout the clinical study to better plan clinical supply budgets and project timelines. Explore how to identify potential supply-related issues before they can negatively impact your study.

Events