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July 14, 2017

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Today's Rundown

  1. Cash-rich Gilead should consider Incyte takeover, but it won't come cheap

  2. Akcea cuts share price, ups volume to get $125M IPO away

  3. Mayo Clinic startup raises series A round for AI-driven R&D

  4. One step closer to a Zika vaccine for pregnant women

  5. Bigfoot picks Abbott glucose sensor for insulin delivery tech

  6. EuroBiotech Report—Novartis CAR-T, Shire-Roche, Zealand IPO, Erytech alliance and Enterome-Nestlé joint venture

  7. FiercePharmaAsia—Gilead’s API lawsuit, Biocon plant concerns, AstraZeneca’s Chinese business

  8. Chutes & Ladders—AstraZeneca chief Soriot may abscond to Teva

Featured Story

Cash-rich Gilead should consider Incyte takeover, but it won't come cheap

With investors clamoring for a deal to broaden its focus, Gilead could do a lot worse than make a bid for Incyte, say analysts at Leerink, though they admit it could be a pricey deal given Incyte's $28 billion enterprise value.

Top Stories

Akcea cuts share price, ups volume to get $125M IPO away

Akcea Therapeutics has set the terms for its $125 million IPO. The Ionis Pharmaceuticals spinout priced the IPO well below its target range but made up the shortfall by selling 62% more shares than it originally planned.

Mayo Clinic startup raises series A round for AI-driven R&D

Mayo Clinic and Nference have created an AI-driven R&D startup. The biotech, Qrativ, is starting life with $8.3 million in series A funds, access to its founders’ AI platform and clinical data and a remit to identify treatments for rare diseases. 

One step closer to a Zika vaccine for pregnant women

A pair of Zika vaccines, given to mice before pregnancy, protected their offspring from Zika infection. The study is a step toward tangible protection for pregnant women, who risk fetal brain defects if they are exposed to the virus.

Bigfoot picks Abbott glucose sensor for insulin delivery tech

Abbott has struck a deal to combine its FreeStyle Libre glucose sensing technology with Bigfoot Biomedical’s experimental insulin delivery device. The agreement sets Bigfoot up to start a pivotal trial of a version of its delivery system that incorporates the Abbott technology next year. 

EuroBiotech Report—Novartis CAR-T, Shire-Roche, Zealand IPO, Erytech alliance and Enterome-Nestlé joint venture

In this week's EuroBiotech Report, Novartis aces CAR-T panel, Shire hits Roche with injunction, Zealand files for IPO and more.

FiercePharmaAsia—Gilead’s API lawsuit, Biocon plant concerns, AstraZeneca’s Chinese business

A whistleblower lawsuit alleging Gilead used an unapproved API from China has been revived, Biocon and Mylan's Herceptin biosimilar is delayed in Europe due to plant issues, AstraZeneca is boosting production at its Australian site to meet rising respiratory demands in China, and more.

Chutes & Ladders—AstraZeneca chief Soriot may abscond to Teva

AstraZeneca CEO Pascal Soriot was said to be filling the CEO post at Teva, GSK poached Pfizer's medicinal sciences head Tony Wood, and Advaxis CEO O'Connor abruptly resigned. Plus more hirings, firings and retirings throughout the industry.

News of Note

Shares in MorphoSys jumped after the FDA approved a Johnson & Johnson drug that will give it royalties. Article

Innate Pharma completed the acquisition of an anti-C5aR antibody from Novo Nordisk. Statement

Celltrion is looking to buy U.S. biotechs with pipelines of new drugs. Article (in Korean)

Resources

[Webinar] Results from the 2017 Unified Clinical Operations Survey

Learn why 99% of respondents report the need to unify their clinical applications, including CTMS, EDC, eTMF, and study start-up.

[Whitepaper] The State of Digital Identification and Signatures

When leading biopharma companies founded SAFE-BioPharma in 2005, it was with a vision of a not too distant future with major changes in the industry: the move to collaboration with many partners, make business processes fully electronic, and to take advantage of all of the benefits of online operations.

[Whitepaper] Industry Report: Findings from the 2017 Unified Clinical Operations Survey

Learn why 99% of respondents report the need to unify their clinical applications, including CTMS, EDC, eTMF, and study start-up.

[Whitepaper] Make Your Clinical Trials a Success

Gain critical insights into how to design and implement pragmatic trials and generate relevant, high-level real-world evidence. Learn when to conduct PTs, design considerations, ethical regulatory issues — and more.

[Whitepaper] Enable better radiation therapy study results

Discover the factors that contribute to differential radiation sensitivity between the Rag2 and SCID models.

[Webinar] Within-Subject Clinical Trials: Intro to New Methods & Stat. Models

In this webinar, we will introduce the rapidly-evolving within-subject clinical trial (WSCT) methods for early phase evidence generation that require fewer people, less time, and usually less funding than traditional early phase methods.

[Webinar] Leveraging Medical Insights for Better Healthcare Engagement

Join this global webinar to learn a new approach for demonstrating medical affairs' impact with better metrics - beyond reach and frequency, enabling launch success and better engagement with strategic KOL insights, and increasing your organization's share of voice in the healthcare landscape.

[Whitepaper] The Paperless Future of Healthcare and Life Sciences

DocuSign’s eSignature solutions modernize healthcare and life science organizations by eliminating paper and antiquated signature processes while meeting compliance requirements and reducing costs and errors.

[Whitepaper] DocuSign Life Sciences eBook: Reducing Cycle Time with Digital Transaction Management

The patients who rely on your scientific leadership are expecting more.

[Whitepaper] Streamline Regulatory Compliance in Life Sciences with Digital Transaction Management

The U.S. Department of Justice has collected upwards of $17 billion in settlements from the healthcare industry since 2009, including more than $2 billion from a single life sciences company.

Events

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