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July 19, 2018

Today's Rundown

Featured Story

Gilead’s Kite bags option to buy gamma delta startup Gadeta

Gilead’s Kite Pharma has snagged an option to buy gamma delta T-cell receptor startup Gadeta. The deal sees Kite take a stake in Gadeta and commit to milestones tied to the progress of oncology candidates.

Top Stories

Novartis pays €95M to bag dermatitis drug from Galapagos, MorphoSys

Novartis is set to pay €95 million ($110 million) upfront for the global rights to Galapagos and MorphoSys’ anti-IL-17C antibody MOR106. The deal positions Novartis to take MOR106 forward in atopic dermatitis and other indications, handing over up to €850 million in milestones as it goes.

Stripped-down Vical ‘considering options’ after pipeline woes

After a string of pipeline failures, Vical has called in advisers to help decide the future of the company. The move comes just over a month after Vical abandoned work on a genital herpes vaccine following a negative phase 2 trial.

Gritstone, Bristol-Myers Squibb to trial immunotherapy combos in solid tumors

Gritstone Oncology and Bristol-Myers Squibb will test the former's personalized neoantigen treatment in combination with the latter's Opdivo and Yervoy in patients with advanced solid tumors.

IFM Therapeutics' inflammation-focused subsidiary debuts with $31M

IFM Therapeutics is hiving off its NLRP3 stable into a subsidiary dubbed IFM Tre, which expects to advance its lead asset into phase 1 next year.

Johns Hopkins startup Neuraly plans phase 1 Parkinson’s trial with $36M round

A new startup from Johns Hopkins has launched with $36 million in financing, in the pursuit of disease-modifying agents for Parkinson’s disease and other neurodegenerative disorders.

Hospital antibiotic developer Aridis files for $34.5M IPO

Immunotherapy developer Aridis Pharmaceuticals has filed for a $34.5 million IPO as it plans to move its fully human antibodies for hospital-related infections into late-phase clinical trials.

Resources

[Whitepaper] How early planning and a unified data platform can cut trial timelines and cost.

Accelerate Clinical Research as Study Complexity Grows

[Whitepaper] eClinical Landscape Study - CRO Report from Tufts Center for the Study of Drug Development

See results from the Tufts eClinical Landscape Study – CRO Report on current data management practices, goals, and challenges for contract research organizations (CROs).

[Whitepaper] Digitizing the Global Life Sciences Supply Chain: The Critical Role of Digital Transaction Management

Life science companies are experiencing a significant transformation in how they bring new products to market.

[Whitepaper] Rise in Targeted Therapies Drives Needs for Small Volume Manufacturing

Biologics, orphan drugs, and precision medicine are on the rise, and that means some big changes for drug development and manufacturing companies. What should pharma companies look for when navigating this new era of small-volume manufacturing? Here are some ideas to consider when developing a new manufacturing strategy.

Events

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